| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $39,093 | -46.3% | 13 | -1 | $3,007 | $1,139,765 | 5 | Universal Pictures International (UPI) | false | false |
| 2 | - | The Taking of Pelham 123 | $15,253 | - | 7 | - | $2,179 | $15,590 | 1 | Sony Pictures Releasing | true | false |
| 3 | 3 | Harry Potter and the Half-Blood Prince | $14,995 | -53.6% | 8 | +1 | $1,874 | $231,133 | 2 | Garsu Pasaulio Irasai | false | false |
| 4 | 2 | Brüno | $13,608 | -75.8% | 7 | - | $1,944 | $98,279 | 2 | ACME | false | false |
| 5 | - | Hannah Montana: The Movie | $5,657 | - | 3 | - | $1,885 | $5,972 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 6 | The Hangover | $4,450 | -26.9% | 5 | - | $890 | $283,308 | 8 | - | false | false |
| 7 | - | Easy Virtue | $3,295 | - | 2 | - | $1,647 | $5,861 | 1 | ACME | true | false |
| 8 | 5 | The Last House on the Left | $2,625 | -59.6% | 3 | - | $875 | $15,246 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 4 | Public Enemies | $2,397 | -66.2% | 7 | - | $342 | $80,359 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | Transformers: Revenge of the Fallen | $1,893 | -58.4% | 5 | -3 | $378 | $218,689 | 6 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | Gomorrah | $1,482 | -59.6% | 2 | - | $741 | $18,803 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | 8 | The Proposal | $1,352 | -69.1% | 5 | -2 | $270 | $153,050 | 7 | Universal Pictures International (UPI) | false | false |
| 13 | - | The Uninvited | $388 | - | 1 | - | $388 | $22,227 | 11 | Universal Pictures International (UPI) | false | false |
| 14 | - | Bolt | $90 | - | 3 | - | $30 | $338,908 | 23 | Universal Pictures International (UPI) | false | false |
| 15 | - | Ratatouille | $22 | - | 1 | - | $22 | $636,521 | 103 | Universal Pictures International (UPI) | false | false |
| 16 | - | Beverly Hills Chihuahua | $17 | - | 1 | - | $17 | $137,969 | 26 | Universal Pictures International (UPI) | false | false |
