| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Half-Blood Prince | $67,316 | -46.6% | 28 | -4 | $2,404 | $309,552 | 2 | Warner Bros. | false | false |
| 2 | 2 | Ice Age: Dawn of the Dinosaurs | $41,525 | -50.2% | 20 | -7 | $2,076 | $563,138 | 4 | 20th Century Fox International | false | false |
| 3 | - | The Uninvited | $22,237 | - | 11 | - | $2,021 | $22,237 | 1 | United International Pictures | true | false |
| 4 | - | State of Play | $15,606 | - | 7 | - | $2,229 | $15,606 | 1 | United International Pictures | true | false |
| 5 | 3 | The Proposal | $14,800 | -28.9% | 12 | -3 | $1,233 | $103,337 | 3 | Walt Disney Pictures | false | false |
| 6 | 4 | Transformers: Revenge of the Fallen | $10,578 | -45.8% | 13 | -5 | $813 | $494,428 | 5 | United International Pictures | false | false |
| 7 | - | Vicky Cristina Barcelona | $4,051 | - | 3 | - | $1,350 | $4,051 | 1 | N/A | true | false |
| 8 | 5 | The Last House on the Left | $1,319 | -78.6% | 4 | -7 | $329 | $31,967 | 3 | United International Pictures | false | false |
| 9 | 11 | Paul Blart: Mall Cop | $1,190 | +366.7% | 2 | - | $595 | $279,103 | 16 | Sony Pictures Releasing | false | false |
| 10 | 6 | Up | $822 | -59.8% | 4 | -1 | $205 | $299,390 | 7 | Walt Disney Pictures | false | false |
| 11 | 9 | The Reader | $359 | -14.7% | 1 | - | $359 | $35,148 | 6 | N/A | false | false |
| 12 | 10 | Terminator Salvation | $205 | -43.4% | 1 | -2 | $205 | $1,024,758 | 8 | Sony Pictures Releasing | false | false |
| 13 | 8 | Night at the Museum: Battle of the Smithsonian | $91 | -80.5% | 1 | -1 | $91 | $307,697 | 10 | 20th Century Fox International | false | false |
