| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $106,728 | - | 7 | - | $15,246 | $106,728 | 1 | Warner Bros. | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $48,659 | -25.5% | 6 | - | $8,109 | $444,943 | 4 | 20th Century Fox International | false | false |
| 3 | 3 | Omar & Salma | $32,257 | -15.7% | 9 | - | $3,584 | $617,500 | 7 | N/A | false | false |
| 4 | 2 | The Hangover | $30,296 | -34% | 6 | - | $5,049 | $206,477 | 3 | Warner Bros. | false | false |
| 5 | 4 | The Proposal | $19,784 | -18.3% | 6 | - | $3,297 | $264,809 | 6 | Walt Disney Pictures | false | false |
| 6 | 5 | Bobbos | $17,074 | -17.9% | 7 | - | $2,439 | $89,730 | 3 | N/A | false | false |
| 7 | 7 | Transformers: Revenge of the Fallen | $14,821 | -1.9% | 6 | - | $2,470 | $250,842 | 5 | United International Pictures | false | false |
| 8 | 6 | 17 Again | $14,577 | -22.8% | 4 | +1 | $3,644 | $45,189 | 2 | N/A | false | false |
| 9 | 8 | Red Cliff | $6,511 | -22.1% | 4 | -1 | $1,627 | $22,133 | 2 | Jaguar Film International Distribution | false | false |
| 10 | 11 | My Life in Ruins | $4,798 | +26.1% | 1 | - | $4,798 | $48,061 | 5 | Prime Pictures | false | false |
| 11 | 20 | Obsessed | $893 | +25.4% | 2 | - | $446 | $18,247 | 4 | Sony Pictures Releasing | false | false |
| 12 | 23 | The Taking of Pelham 123 | $306 | +2.3% | 1 | - | $306 | $73,871 | 7 | Sony Pictures Releasing | false | false |
| 13 | 24 | Angels & Demons | $220 | -13% | 1 | - | $220 | $189,254 | 11 | Sony Pictures Releasing | false | false |
