| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $126,102 | - | 32 | - | $3,940 | $126,102 | 1 | Warner Bros. | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $83,449 | -21.5% | 27 | -4 | $3,090 | $483,148 | 3 | 20th Century Fox International | false | false |
| 3 | 3 | The Proposal | $20,823 | -36.9% | 15 | - | $1,388 | $72,729 | 2 | Walt Disney Pictures | false | false |
| 4 | 2 | Transformers: Revenge of the Fallen | $19,524 | -41% | 18 | -7 | $1,084 | $474,539 | 4 | United International Pictures | false | false |
| 5 | 4 | The Last House on the Left | $6,173 | -55.1% | 11 | -1 | $561 | $26,252 | 2 | United International Pictures | false | false |
| 6 | 6 | Up | $2,044 | -47.1% | 5 | -5 | $408 | $298,075 | 6 | Walt Disney Pictures | false | false |
| 7 | 13 | Duplicity | $489 | +179.4% | 1 | - | $489 | $47,118 | 8 | United International Pictures | false | false |
| 8 | 11 | Night at the Museum: Battle of the Smithsonian | $466 | +8.1% | 2 | - | $233 | $307,542 | 9 | 20th Century Fox International | false | false |
| 9 | 8 | The Reader | $421 | -79.3% | 1 | -2 | $421 | $34,416 | 5 | N/A | false | false |
| 10 | 7 | Terminator Salvation | $362 | -87.4% | 3 | -9 | $120 | $1,024,236 | 7 | Sony Pictures Releasing | false | false |
| 11 | 5 | Paul Blart: Mall Cop | $255 | -94% | 2 | -6 | $127 | $277,295 | 15 | Sony Pictures Releasing | false | false |
