| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $1,218,763 | - | 87 | - | $14,008 | $1,633,771 | 1 | Warner Bros. | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $1,114,168 | -2.2% | 55 | - | $20,257 | $4,885,178 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | Grade 3 | $237,711 | -25.9% | 53 | -12 | $4,485 | $709,496 | 2 | N/A | false | false |
| 4 | 3 | Up | $236,660 | +14.3% | 42 | -8 | $5,634 | $3,256,204 | 6 | Walt Disney Pictures | false | false |
| 5 | 4 | Transformers: Revenge of the Fallen | $142,104 | -30% | 38 | -42 | $3,739 | $1,861,922 | 4 | United International Pictures | false | false |
| 6 | 5 | Summer Hours | $20,985 | +19.2% | 2 | - | $10,492 | $66,687 | 3 | Transeuropa | false | false |
| 7 | 6 | Angels & Demons | $2,886 | -70.2% | 1 | -7 | $2,886 | $2,207,102 | 10 | Sony Pictures Releasing | false | false |
| 8 | 9 | Duplicity | $2,310 | -54.8% | 1 | -1 | $2,310 | $144,527 | 8 | United International Pictures | false | false |
| 9 | 10 | Teresa: Crucificada por amar | $2,139 | -55.8% | 2 | -4 | $1,069 | $64,200 | 5 | N/A | false | false |
| 10 | 11 | Night at the Museum: Battle of the Smithsonian | $678 | +18.9% | 1 | -2 | $678 | $1,381,208 | 9 | 20th Century Fox International | false | false |
