| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Brüno | $4,561,742 | - | 334 | - | $13,657 | $5,846,790 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 2 | Ice Age: Dawn of the Dinosaurs | $4,307,005 | -8% | 425 | +3 | $10,134 | $13,897,868 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | Transformers: Revenge of the Fallen | $2,894,538 | -42% | 457 | +1 | $6,333 | $26,221,043 | 3 | Paramount Pictures International | false | false |
| 4 | 5 | Hannah Montana: The Movie | $1,426,294 | +33.1% | 269 | +81 | $5,302 | $5,220,360 | 3 | Walt Disney Pictures | false | false |
| 5 | 3 | The Hangover | $1,128,266 | -31.5% | 214 | -14 | $5,272 | $13,076,783 | 5 | Warner Bros. | false | false |
| 6 | 4 | The Proposal | $1,127,431 | -30.5% | 267 | -9 | $4,222 | $10,437,469 | 4 | Walt Disney Pictures | false | false |
| 7 | 6 | Year One | $272,919 | -46.3% | 165 | -20 | $1,654 | $4,018,362 | 4 | Sony Pictures Releasing | false | false |
| 8 | 7 | Coco Before Chanel | $228,081 | -18.1% | 26 | - | $8,772 | $1,059,388 | 3 | Roadshow Films | false | false |
| 9 | 8 | Night at the Museum: Battle of the Smithsonian | $176,746 | -19.5% | 118 | -48 | $1,497 | $13,205,974 | 8 | 20th Century Fox International | false | false |
| 10 | 9 | Terminator Salvation | $101,535 | -53.3% | 86 | -67 | $1,180 | $11,544,978 | 6 | Sony Pictures Releasing | false | false |
| 11 | 13 | Disgrace | $88,398 | -15% | 33 | +3 | $2,678 | $653,854 | 4 | Icon Film Distribution | false | false |
| 12 | 10 | Land of the Lost | $67,848 | -49.3% | 79 | -85 | $858 | $3,108,970 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | 12 | State of Play | $67,104 | -42.7% | 61 | -16 | $1,100 | $5,334,512 | 7 | Universal Pictures International (UPI) | false | false |
| 14 | 14 | Angels & Demons | $55,503 | -44.6% | 47 | -18 | $1,180 | $13,982,936 | 9 | Sony Pictures Releasing | false | false |
| 15 | 16 | Samson & Delilah | $50,515 | -16.7% | 32 | +2 | $1,578 | $2,069,134 | 10 | Paramount Pictures International | false | false |
| 16 | 15 | Last Ride | $46,549 | -23.6% | 16 | - | $2,909 | $148,161 | 2 | Madman Entertainment | false | false |
| 17 | 11 | Kambakkht Ishq | $37,287 | -69.3% | 17 | - | $2,193 | $198,579 | 2 | Eros Worldwide | false | false |
| 18 | 17 | Sunshine Cleaning | $32,417 | -41.1% | 37 | -4 | $876 | $671,843 | 5 | Madman Entertainment | false | false |
| 19 | - | The Fox and the Child | $32,015 | - | 9 | - | $3,557 | $36,804 | 1 | Hopscotch Films | true | false |
| 20 | 20 | Under the Sea 3D | $31,691 | -12.4% | 2 | - | $15,845 | $801,048 | 20 | IMAX | false | false |
| 21 | - | Winged Creatures | $22,689 | - | 9 | - | $2,521 | $22,689 | 1 | Icon Film Distribution | true | false |
| 22 | - | My Friends, My Love 2009 Re-release | $4,214 | - | 9 | - | $468 | $4,214 | - | Hopscotch Films | - | false |
| 23 | - | Mother | $3,442 | - | 1 | - | $3,442 | $3,442 | 1 | Madman Entertainment | true | false |
| 24 | - | The Burning Season | $2,995 | - | 3 | - | $998 | $2,995 | 1 | Gil Scrine Films | true | false |
