| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $1,380,911 | - | 240 | - | $5,753 | $1,734,815 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $509,828 | -52.8% | 108 | - | $4,720 | $2,308,787 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | The Proposal | $272,020 | -36% | 84 | - | $3,238 | $1,614,230 | 3 | Walt Disney Pictures | false | false |
| 4 | 3 | The Hangover | $266,479 | -32.6% | 67 | - | $3,977 | $2,487,219 | 4 | Warner Bros. | false | false |
| 5 | - | Drag Me to Hell | $136,486 | - | 40 | - | $3,412 | $170,861 | 1 | RCV Film Distribution | true | false |
| 6 | 4 | Angels & Demons | $116,503 | -27.4% | 108 | -15 | $1,078 | $7,216,979 | 8 | Sony Pictures Releasing | false | false |
| 7 | 5 | Terminator Salvation | $33,622 | -63.5% | 35 | -51 | $960 | $2,030,741 | 5 | Sony Pictures Releasing | false | false |
| 8 | 7 | State of Play | $26,738 | -56.9% | 36 | -12 | $742 | $285,824 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 6 | Night at the Museum: Battle of the Smithsonian | $26,711 | -68.2% | 82 | -17 | $325 | $2,216,072 | 7 | Warner Bros. | false | false |
| 10 | 8 | Coco Before Chanel | $23,310 | -37.4% | 29 | -1 | $803 | $709,234 | 6 | RCV Film Distribution | false | false |
| 11 | 16 | The Reader | $10,925 | -24.5% | 24 | -10 | $455 | $1,879,143 | 14 | Benelux Film Distributors | false | false |
| 12 | 15 | Disgrace | $10,362 | -28.6% | 11 | - | $942 | $169,053 | 5 | A-Film Distribution | false | false |
| 13 | 9 | 17 Again | $9,033 | -67.9% | 31 | -25 | $291 | $2,280,598 | 11 | RCV Film Distribution | false | false |
| 14 | 10 | The Last House on the Left | $8,800 | -65.5% | 10 | -9 | $880 | $234,129 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 14 | Chéri | $8,186 | -49.1% | 18 | -1 | $454 | $35,641 | 2 | Benelux Film Distributors | false | false |
| 16 | 20 | The Girl on the Train | $6,713 | -31.1% | 11 | - | $610 | $47,271 | 3 | Benelux Film Distributors | false | false |
| 17 | 11 | Beverly Hills Chihuahua | $6,136 | -73.4% | 57 | -3 | $107 | $948,809 | 11 | Walt Disney Pictures | false | false |
| 18 | 18 | Slumdog Millionaire | $5,728 | -51.8% | 27 | -11 | $212 | $5,268,767 | 21 | Cinéart | false | false |
| 19 | - | Sunshine Cleaning | $5,579 | - | 10 | - | $557 | $360,566 | 8 | A-Film Distribution | false | false |
| 20 | 13 | Duplicity | $4,919 | -70.2% | 10 | -17 | $491 | $564,468 | 6 | Universal Pictures International (UPI) | false | false |
