| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Knowing | $17,415 | - | 6 | - | $2,902 | $19,185 | 1 | N/A | true | false |
| 2 | 1 | Up | $16,797 | -64.1% | 10 | - | $1,679 | $173,372 | 4 | Walt Disney Pictures | false | false |
| 3 | - | Transformers: Revenge of the Fallen | $11,518 | - | 6 | - | $1,919 | $16,010 | 1 | Paramount Pictures International | true | false |
| 4 | - | The Reader | $11,343 | - | 5 | - | $2,268 | $25,169 | 1 | N/A | true | false |
| 5 | 2 | Música en espera | $9,776 | -58.9% | 5 | - | $1,955 | $39,415 | 2 | N/A | false | false |
| 6 | 3 | Angels & Demons | $6,724 | -60.1% | 6 | -2 | $1,120 | $300,824 | 7 | Sony Pictures Releasing | false | false |
| 7 | - | State of Play | $6,305 | - | 6 | - | $1,050 | $6,305 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | - | 17 Again | $5,544 | - | 4 | - | $1,386 | $5,544 | 1 | N/A | true | false |
| 9 | 4 | Night at the Museum: Battle of the Smithsonian | $5,286 | -67.5% | 6 | - | $881 | $134,828 | 6 | 20th Century Fox International | false | false |
| 10 | - | The Merry Widow | $4,550 | - | 3 | - | $1,516 | $4,550 | 1 | N/A | true | false |
| 11 | 5 | Hannah Montana: The Movie | $3,894 | -69.8% | 5 | -1 | $778 | $18,268 | 2 | Walt Disney Pictures | false | false |
| 12 | 6 | Terminator Salvation | $3,523 | -72.3% | 7 | -2 | $503 | $81,676 | 4 | Sony Pictures Releasing | false | false |
| 13 | 7 | He's Just Not That Into You | $3,458 | -69.9% | 7 | +2 | $494 | $72,892 | 5 | N/A | false | false |
| 14 | 8 | Fast & Furious | $1,775 | -73.6% | 1 | -3 | $1,775 | $54,936 | 5 | Universal Pictures International (UPI) | false | false |
| 15 | 9 | Giant | $1,420 | -69.7% | 4 | +1 | $355 | $45,871 | 6 | N/A | false | false |
| 16 | - | El ratón Pérez 2 | $1,414 | - | 7 | - | $202 | $1,414 | 1 | Walt Disney Pictures | true | false |
| 17 | 16 | A Christmas Tale | $354 | -63% | 1 | - | $354 | $4,382 | 3 | N/A | false | false |
| 18 | 14 | Grace Is Gone | $342 | -66.6% | 1 | - | $342 | $5,026 | 3 | N/A | false | false |
| 19 | 17 | La mañana siguiente | $328 | -56.3% | 2 | - | $164 | $4,173 | 4 | N/A | false | false |
| 20 | 15 | Fados | $281 | -71.7% | 1 | - | $281 | $16,482 | 8 | N/A | false | false |
| 21 | 20 | The Women | $108 | -58.8% | 1 | -1 | $108 | $7,226 | 4 | N/A | false | false |
| 22 | 18 | Earth | $28 | -91.2% | 1 | - | $28 | $14,480 | 10 | Walt Disney Pictures | false | false |
