| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Terminator Salvation | $119,105 | -36.3% | 95 | -5 | $1,253 | $884,049 | 3 | Sony Pictures Releasing | false | false |
| 2 | 2 | Up | $63,397 | -42.8% | 22 | -4 | $2,881 | $208,765 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Angels & Demons | $21,763 | -48% | 25 | -21 | $870 | $1,426,951 | 6 | Sony Pictures Releasing | false | false |
| 4 | 4 | Night at the Museum: Battle of the Smithsonian | $15,968 | -35.9% | 17 | -1 | $939 | $285,669 | 5 | 20th Century Fox International | false | false |
| 5 | - | Paul Blart: Mall Cop | $13,597 | - | 8 | - | $1,699 | $247,917 | 11 | Sony Pictures Releasing | false | false |
| 6 | - | Push | $11,366 | - | 11 | - | $1,033 | $11,366 | 1 | N/A | true | false |
| 7 | - | The Reader | $9,199 | - | 7 | - | $1,314 | $9,199 | 1 | N/A | true | false |
| 8 | 5 | Ghosts of Girlfriends Past | $5,177 | -34.5% | 7 | -1 | $739 | $92,762 | 5 | Warner Bros. | false | false |
| 9 | 6 | Talento de barrio | $2,617 | -65.7% | 6 | -2 | $436 | $13,200 | 2 | N/A | false | false |
| 10 | 7 | Duplicity | $2,617 | -29.8% | 2 | - | $1,308 | $42,351 | 4 | United International Pictures | false | false |
| 11 | 9 | The Unborn | $400 | -33.3% | 1 | -1 | $400 | $89,568 | 7 | United International Pictures | false | false |
| 12 | 11 | Knowing | $379 | +25.9% | 1 | - | $379 | $62,620 | 7 | N/A | false | false |
| 13 | 8 | Hannah Montana: The Movie | $221 | -81.7% | 1 | -4 | $221 | $64,766 | 6 | Walt Disney Pictures | false | false |
| 14 | 10 | Doubt | $196 | -40.2% | 1 | - | $196 | $118,185 | 6 | Walt Disney Pictures | false | false |
