| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 2009 Re-release | $74,070 | -33.4% | 8 | - | $9,258 | $232,116 | 2 | N/A | false | false |
| 2 | - | The Proposal | $29,319 | - | 6 | - | $4,886 | $29,319 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | Up | $22,608 | +6.1% | 6 | - | $3,768 | $55,378 | 2 | Walt Disney Pictures | false | false |
| 4 | 3 | The Taking of Pelham 123 | $10,150 | -48.2% | 6 | - | $1,691 | $38,643 | 2 | Sony Pictures Releasing | false | false |
| 5 | 4 | Angels & Demons | $8,174 | -29.8% | 7 | - | $1,167 | $171,613 | 6 | Sony Pictures Releasing | false | false |
| 6 | 5 | State of Play | $6,457 | -12.7% | 4 | -2 | $1,614 | $59,961 | 4 | United International Pictures | false | false |
| 7 | - | The Heir Apparent: Largo Winch | $6,117 | - | 4 | - | $1,529 | $6,117 | 1 | N/A | true | false |
| 8 | 7 | Two Lovers | $4,439 | -26.7% | 4 | -1 | $1,109 | $13,040 | 2 | N/A | false | false |
| 9 | 6 | Night at the Museum: Battle of the Smithsonian | $4,414 | -39.1% | 5 | -1 | $882 | $70,039 | 5 | 20th Century Fox International | false | false |
| 10 | 9 | Terminator Salvation | $4,376 | -6.9% | 3 | - | $1,458 | $73,303 | 5 | N/A | false | false |
| 11 | - | Make It Happen | $4,087 | - | 4 | - | $1,021 | $4,087 | 1 | N/A | true | false |
| 12 | 10 | Crank: High Voltage | $3,700 | -20.4% | 4 | - | $925 | $9,927 | 2 | N/A | false | false |
| 13 | 11 | Coraline | $2,176 | -42.5% | 1 | - | $2,176 | $47,333 | 6 | United International Pictures | false | false |
| 14 | 8 | I Love You, Man | $1,934 | -67.4% | 3 | -1 | $644 | $67,910 | 4 | United International Pictures | false | false |
| 15 | - | Franklyn | $1,485 | - | 5 | - | $297 | $1,485 | 1 | Italian International Film | true | false |
| 16 | - | Towelhead | $952 | - | 1 | - | $952 | $952 | 1 | Prime Pictures | true | false |
| 17 | 13 | Knowing | $697 | +11.2% | 1 | - | $697 | $113,649 | 10 | Jaguar Film International Distribution | false | false |
| 18 | 18 | Defiance | $352 | -9% | 2 | - | $176 | $25,719 | 6 | N/A | false | false |
| 19 | 12 | X-Men Origins: Wolverine | $265 | -87.2% | 1 | -1 | $265 | $83,627 | 8 | 20th Century Fox International | false | false |
| 20 | 21 | Hannah Montana: The Movie | $183 | -31.5% | 1 | -2 | $183 | $125,486 | 11 | Walt Disney Pictures | false | false |
| 21 | 20 | It's Alive | $163 | -41.8% | 1 | - | $163 | $22,962 | 9 | Italian International Film | false | false |
| 22 | 14 | New in Town | $149 | -72.6% | 2 | - | $74 | $17,071 | 5 | N/A | false | false |
| 23 | 26 | Ramadhan Mabrook Abul-Alamain Hammudah | $133 | +392.6% | 1 | - | $133 | $51,670 | 11 | N/A | false | false |
| 24 | 22 | Charbel | $107 | -51.4% | 1 | -1 | $107 | $314,738 | 20 | Italian International Film | false | false |
| 25 | 16 | Finding Amanda | $96 | -75.9% | 1 | -2 | $96 | $7,795 | 4 | Italian International Film | false | false |
| 26 | 24 | Frozen River | $74 | -39.8% | 1 | - | $74 | $7,610 | 7 | Prime Pictures | false | false |
