| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Hangover | $51,264 | -16.2% | 6 | - | $8,544 | $225,931 | 2 | Warner Bros. | false | false |
| 2 | - | Year One | $24,833 | - | 6 | - | $4,138 | $24,833 | 1 | Sony Pictures Releasing | true | false |
| 3 | 3 | Ghosts of Girlfriends Past | $6,021 | -44.2% | 4 | - | $1,505 | $36,238 | 2 | N/A | false | false |
| 4 | 4 | Angels & Demons | $5,032 | -38.3% | 5 | - | $1,006 | $276,433 | 6 | Sony Pictures Releasing | false | false |
| 5 | 2 | Terminator Salvation | $4,358 | -63.4% | 4 | -1 | $1,089 | $115,244 | 3 | Sony Pictures Releasing | false | false |
| 6 | 5 | Night at the Museum: Battle of the Smithsonian | $3,417 | -42% | 4 | -1 | $854 | $92,619 | 5 | 20th Century Fox International | false | false |
| 7 | 7 | Unstable Fables: The Goldilocks and the 3 Bears Show | $2,283 | -21.3% | 3 | -2 | $761 | $6,126 | 2 | N/A | false | false |
| 8 | 6 | Coraline | $2,070 | -30.8% | 2 | - | $1,035 | $25,183 | 4 | United International Pictures | false | false |
| 9 | 9 | The True Story of Puss'N Boots | $1,085 | -16.5% | 3 | -1 | $361 | $36,900 | 8 | N/A | false | false |
| 10 | 10 | Management | $1,078 | -4.1% | 2 | - | $539 | $16,232 | 3 | N/A | false | false |
| 11 | 8 | Adventureland | $881 | -40.8% | 2 | - | $440 | $35,557 | 4 | Walt Disney Pictures | false | false |
| 12 | 11 | Hannah Montana: The Movie | $804 | -19.9% | 1 | -1 | $804 | $28,327 | 6 | Walt Disney Pictures | false | false |
| 13 | 12 | Star Trek | $416 | -57.2% | 1 | - | $416 | $103,834 | 7 | United International Pictures | false | false |
| 14 | 13 | The Last House on the Left | $338 | -62.9% | 2 | -1 | $169 | $46,390 | 5 | N/A | false | false |
| 15 | 14 | Dreamland | $233 | -67.7% | 1 | - | $233 | $123,238 | 11 | N/A | false | false |
| 16 | 16 | X-Men Origins: Wolverine | $154 | -57% | 1 | -6 | $154 | $126,349 | 8 | 20th Century Fox International | false | false |
| 17 | 17 | Let the Right One In | $49 | -50.5% | 1 | - | $49 | $15,808 | 10 | N/A | false | false |
