| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Taking of Pelham 123 | $265,109 | - | 50 | - | $5,302 | $343,593 | - | Sony Pictures Releasing | - | false |
| 2 | 1 | Terminator Salvation | $159,534 | -55.9% | 92 | -21 | $1,734 | $3,066,739 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | The Hangover | $91,603 | - | 16 | - | $5,725 | $116,783 | 1 | Warner Bros. | true | false |
| 4 | 2 | Angels & Demons | $77,196 | -54.6% | 45 | -30 | $1,715 | $3,974,880 | 5 | Sony Pictures Releasing | false | false |
| 5 | - | Blood: The Last Vampire | $53,193 | - | 16 | - | $3,324 | $73,767 | 1 | N/A | true | false |
| 6 | 3 | Night at the Museum: Battle of the Smithsonian | $46,046 | -53.6% | 15 | -1 | $3,069 | $1,592,693 | 4 | 20th Century Fox International | false | false |
| 7 | 4 | Duplicity | $25,244 | -63.9% | 17 | - | $1,484 | $161,707 | 2 | United International Pictures | false | false |
| 8 | 5 | Ghosts of Girlfriends Past | $22,599 | -60% | 13 | - | $1,738 | $138,114 | 2 | N/A | false | false |
| 9 | - | Permanent Residence | $11,004 | - | 4 | - | $2,751 | $15,010 | 1 | N/A | true | false |
| 10 | 6 | Brass Knuckle Boys | $8,227 | -58.8% | 8 | - | $1,028 | $48,061 | 2 | N/A | false | false |
| 11 | - | Teeth | $5,926 | - | 6 | - | $987 | $8,150 | 1 | N/A | true | false |
| 12 | - | Paris 36 | $5,332 | - | 4 | - | $1,333 | $6,261 | 1 | N/A | true | false |
| 13 | - | I've Loved You So Long | $4,440 | - | 4 | - | $1,110 | $5,821 | 1 | N/A | true | false |
| 14 | 7 | 17 Again | $3,317 | -68.1% | 3 | -2 | $1,105 | $735,021 | 7 | Long Shong Entertainment Multimedia Company | false | false |
| 15 | 9 | Home | $2,633 | -59.3% | 1 | -2 | $2,633 | $15,254 | 2 | N/A | false | false |
| 16 | 11 | Dalai Lama Renaissance | $2,284 | -18.3% | 1 | - | $2,284 | $8,738 | 2 | N/A | false | false |
| 17 | 10 | Star Trek | $1,151 | -74.7% | 1 | -2 | $1,151 | $544,033 | 6 | United International Pictures | false | false |
| 18 | 12 | Captain Abu Raed | $983 | -63.8% | 2 | - | $491 | $6,098 | 2 | N/A | false | false |
| 19 | 8 | The Haunting in Connecticut | $757 | -89.2% | 1 | -5 | $757 | $275,453 | 5 | Long Shong Entertainment Multimedia Company | false | false |
| 20 | 13 | Dance Subaru | $574 | -71.4% | 1 | -1 | $574 | $20,223 | 3 | N/A | false | false |
| 21 | 15 | 20th Century Boys 2: The Last Hope | $297 | -76.2% | 1 | - | $297 | $26,554 | 4 | N/A | false | false |
| 22 | 19 | Last Chance Harvey | $161 | -59.4% | 1 | - | $161 | $44,374 | 10 | N/A | false | false |
