| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Hangover | $318,667 | - | 44 | - | $7,242 | $318,667 | 1 | Warner Bros. | true | false |
| 2 | 1 | Terminator Salvation | $270,336 | -59.3% | 77 | - | $3,510 | $1,169,885 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | Night at the Museum: Battle of the Smithsonian | $122,569 | -16.6% | 66 | -1 | $1,857 | $1,250,553 | 4 | 20th Century Fox International | false | false |
| 4 | - | Land of the Lost | $114,954 | - | 44 | - | $2,612 | $114,954 | 1 | United International Pictures | true | false |
| 5 | 3 | Angels & Demons | $71,465 | -36.2% | 64 | -2 | $1,116 | $1,750,361 | 5 | Sony Pictures Releasing | false | false |
| 6 | 4 | Easy Virtue | $56,169 | -23.9% | 38 | +2 | $1,478 | $314,175 | 3 | Hopscotch Films | false | false |
| 7 | 6 | Star Trek | $47,503 | -21.9% | 48 | -5 | $989 | $1,763,735 | 6 | Paramount Pictures International | false | false |
| 8 | 7 | Paul Blart: Mall Cop | $36,763 | -38.6% | 36 | +1 | $1,021 | $262,789 | 3 | Sony Pictures Releasing | false | false |
| 9 | 8 | State of Play | $34,475 | -38.5% | 44 | - | $783 | $286,495 | 3 | United International Pictures | false | false |
| 10 | 5 | I Love You, Man | $30,758 | -57.6% | 39 | - | $788 | $309,782 | 8 | Paramount Pictures International | false | false |
| 11 | - | The Proposal | $18,974 | - | 7 | - | $2,710 | $18,974 | - | Walt Disney Pictures | - | false |
| 12 | 11 | I've Loved You So Long | $18,599 | -3.7% | 9 | - | $2,066 | $180,913 | 5 | Palace Films | false | false |
| 13 | - | Elegy | $16,661 | - | 15 | - | $1,110 | $16,661 | 1 | Hopscotch Films | true | false |
| 14 | 9 | The Topp Twins: Untouchable Girls | $16,426 | -35.8% | 52 | -6 | $315 | $1,117,750 | 10 | Rialto Distribution | false | false |
| 15 | 12 | Last Chance Harvey | $14,031 | -19.8% | 37 | +1 | $379 | $627,041 | 7 | Hoyts Distribution | false | false |
| 16 | 15 | The Reader | $10,878 | -9.8% | 15 | -1 | $725 | $776,265 | 10 | Roadshow Films | false | false |
| 17 | 10 | Knowing | $8,906 | -61.5% | 26 | -18 | $342 | $377,588 | 4 | Hoyts Distribution | false | false |
| 18 | 16 | The Grocer's Son | $8,330 | -1.6% | 18 | +3 | $462 | $212,382 | 8 | Rialto Distribution | false | false |
| 19 | 14 | X-Men Origins: Wolverine | $7,911 | -50.3% | 17 | -25 | $465 | $1,734,164 | 7 | 20th Century Fox International | false | false |
| 20 | 13 | Bottle Shock | $7,359 | -54.7% | 19 | -1 | $387 | $83,264 | 4 | Roadshow Films | false | false |
| 21 | - | The Class | $2,237 | - | 3 | - | $745 | $54,006 | 8 | Sony Pictures Releasing | false | false |
| 22 | - | Rachel Getting Married | $904 | - | 3 | - | $301 | $22,210 | 5 | Sony Pictures Releasing | false | false |
