| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Un'estate ai Caraibi | $1,300,621 | - | 545 | - | $2,386 | $1,301,419 | 1 | Medusa Distribuzione | true | false |
| 2 | 1 | Terminator Salvation | $641,758 | -68.6% | 515 | -1 | $1,246 | $3,652,002 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | Angels & Demons | $422,191 | -64.1% | 382 | -265 | $1,105 | $24,708,736 | 5 | Sony Pictures Releasing | false | false |
| 4 | 2 | Night at the Museum: Battle of the Smithsonian | $419,672 | -64.4% | 294 | -104 | $1,427 | $8,389,892 | 4 | 20th Century Fox International | false | false |
| 5 | 4 | The Girl with the Dragon Tattoo | $299,643 | -62.3% | 266 | -148 | $1,126 | $3,894,655 | 3 | BIM Distribuzione | false | false |
| 6 | - | The Secret of Moonacre | $255,728 | - | 176 | - | $1,453 | $255,728 | 1 | N/A | true | false |
| 7 | - | The Boat That Rocked | $147,492 | - | 99 | - | $1,489 | $147,492 | 1 | United International Pictures | true | false |
| 8 | 6 | Coco Before Chanel | $109,902 | -64.1% | 144 | -20 | $763 | $1,392,284 | 3 | Warner Bros. | false | false |
| 9 | 5 | Vincere | $94,568 | -69.4% | 94 | -133 | $1,006 | $2,557,255 | 4 | 01 Distribution | false | false |
| 10 | 7 | Cash | $62,575 | -76.2% | 106 | -30 | $590 | $444,272 | 2 | N/A | false | false |
| 11 | 8 | My Bloody Valentine | $58,393 | -67.9% | 36 | -42 | $1,622 | $8,342,371 | 6 | Medusa Distribuzione | false | false |
| 12 | - | Filth and Wisdom | $50,900 | - | 72 | - | $706 | $53,429 | 1 | Sacher Distribuzione | true | false |
| 13 | - | Fist of the North Star: The Legends of the True Savior: Legend of Raoh-Chapter of Death in Love 2008 Re-release | $43,221 | - | 36 | - | $1,200 | $43,221 | 50 | Mikado Film | false | false |
| 14 | - | Martyrs | $38,801 | - | 58 | - | $668 | $38,801 | 1 | N/A | true | false |
| 15 | 13 | L'amour | $20,119 | -44.2% | - | - | - | $69,786 | 2 | N/A | false | false |
| 16 | 16 | Questione di cuore | $17,142 | -40.7% | 14 | - | $1,224 | $3,705,215 | 9 | 01 Distribution | false | false |
| 17 | - | The Great Alibi | $12,631 | - | 5 | - | $2,526 | $36,314 | 2 | Medusa Distribuzione | false | false |
| 18 | 9 | 17 Again | $11,730 | -88.4% | 30 | -52 | $391 | $2,174,826 | 5 | Warner Bros. | false | false |
| 19 | 17 | Gran Torino | $11,314 | -60.5% | 7 | -7 | $1,616 | $12,474,465 | 14 | Warner Bros. | false | false |
| 20 | 15 | State of Play | $10,458 | -69.2% | 6 | -12 | $1,743 | $3,330,719 | 7 | United International Pictures | false | false |
| 21 | 11 | Battle for Terra | $9,041 | -82.2% | 41 | -84 | $220 | $297,695 | 3 | Sony Pictures Releasing | false | false |
| 22 | - | Earth | $8,771 | - | 14 | - | $626 | $1,046,151 | 8 | Walt Disney Pictures | false | false |
| 23 | 18 | Cloud 9 | $8,021 | -68.9% | 12 | -5 | $668 | $103,647 | 3 | Warner Bros. | false | false |
| 24 | 12 | Antichrist | $7,468 | -83.9% | 13 | -38 | $574 | $677,007 | 4 | Lucky Red | false | false |
| 25 | - | Cadillac Records | $1,164 | - | 2 | - | $582 | $22,053 | 3 | Sony Pictures Releasing | false | false |
