| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Terminator Salvation | $734,770 | - | 152 | - | $4,834 | $734,770 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Night at the Museum: Battle of the Smithsonian | $371,069 | -35.5% | 94 | +2 | $3,947 | $2,087,411 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | Angels & Demons | $295,296 | -33.9% | 137 | -23 | $2,155 | $2,777,192 | 4 | Sony Pictures Releasing | false | false |
| 4 | - | Last Chance Harvey | $141,972 | - | 22 | - | $6,453 | $141,972 | 1 | Distribution Company | true | false |
| 5 | 3 | The Unborn | $111,768 | -21.3% | 36 | - | $3,104 | $534,740 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Jonas Brothers: The 3D Concert Experience | $76,670 | -13% | 14 | - | $5,476 | $313,395 | 3 | Walt Disney Pictures | false | false |
| 7 | 4 | New in Town | $64,761 | -41.5% | 31 | - | $2,089 | $194,314 | 2 | Distribution Company | false | false |
| 8 | - | Inspector Bellamy | $60,409 | - | 14 | - | $4,314 | $60,409 | 1 | Alfa Films | true | false |
| 9 | 6 | The Reader | $40,854 | -35% | 28 | -3 | $1,459 | $524,873 | 5 | Pachamama Cine | false | false |
| 10 | - | Adventureland | $20,881 | - | 10 | - | $2,088 | $20,881 | 1 | Walt Disney Pictures | true | false |
| 11 | 7 | X-Men Origins: Wolverine | $19,572 | -68% | 27 | -39 | $724 | $1,718,554 | 6 | 20th Century Fox International | false | false |
| 12 | 8 | Earth | $18,369 | -40.8% | 26 | +1 | $706 | $461,534 | 7 | Walt Disney Pictures | false | false |
| 13 | 11 | Duplicity | $14,305 | -43.3% | 22 | -8 | $650 | $583,274 | 7 | Universal Pictures International (UPI) | false | false |
| 14 | 12 | Race to Witch Mountain | $13,163 | -38.9% | 41 | - | $321 | $969,000 | 9 | Walt Disney Pictures | false | false |
| 15 | 9 | 17 Again | $11,138 | -63.9% | 25 | -22 | $445 | $419,562 | 5 | Distribution Company | false | false |
| 16 | 10 | Star Trek | $9,144 | -66.9% | 21 | -9 | $435 | $402,922 | 5 | Paramount Pictures International | false | false |
| 17 | 14 | Fast & Furious | $7,541 | -45.9% | 30 | -6 | $251 | $1,894,428 | 10 | Universal Pictures International (UPI) | false | false |
| 18 | 20 | The Accidental Husband | $5,908 | -36.3% | 8 | -7 | $738 | $223,392 | 6 | Walt Disney Pictures | false | false |
| 19 | 13 | Lorna's Silence | $5,886 | -58.5% | 8 | - | $735 | $84,812 | 4 | Distribution Company | false | false |
| 20 | 21 | Monsters vs. Aliens | $5,868 | -19.2% | 8 | -3 | $733 | $1,595,620 | 10 | Paramount Pictures International | false | false |
| 21 | 18 | The Merry Widow | $5,132 | -52.7% | 9 | +1 | $570 | $150,026 | 8 | Alfa Films | false | false |
| 22 | 19 | Gardens in Autumn 2008 Re-release | $4,862 | -53.6% | 6 | -1 | $810 | $76,217 | 6 | IFA | false | false |
| 23 | 16 | The Artist | $4,328 | -67.3% | 4 | -1 | $1,082 | $20,276 | 2 | Primer Plano Film Group | false | false |
| 24 | 17 | The Class | $3,132 | -72.9% | 4 | -11 | $783 | $301,224 | 8 | Primer Plano Film Group | false | false |
| 25 | 22 | Esperando la carroza 2: Se acabó la fiesta | $2,487 | -65.2% | 8 | -5 | $310 | $1,302,193 | 10 | Primer Plano Film Group | false | false |
| 26 | 24 | Then She Found Me | $1,923 | -64.2% | 6 | -4 | $320 | $77,002 | 6 | Distribution Company | false | false |
| 27 | 27 | Blood Appears | $1,608 | -47.1% | 2 | - | $804 | $23,733 | 4 | N/A | false | false |
| 28 | 28 | Live! | $1,381 | -49.3% | 4 | +1 | $345 | $231,368 | 8 | Distribution Company | false | false |
| 29 | 40 | Mundo alas | $1,000 | +1,049.4% | 2 | +1 | $500 | $35,260 | 11 | Distribution Company | false | false |
| 30 | 26 | Days of May | $853 | -80.6% | 2 | -3 | $426 | $16,506 | 3 | Primer Plano Film Group | false | false |
| 31 | 32 | Dragonball Evolution | $809 | -19.7% | 7 | -2 | $115 | $577,251 | 9 | 20th Century Fox International | false | false |
| 32 | 23 | He's Just Not That Into You | $714 | -87.2% | 8 | +2 | $89 | $1,065,060 | 14 | Distribution Company | false | false |
| 33 | 29 | A Thousand Years of Good Prayers | $690 | -68% | 2 | -3 | $345 | $10,685 | 3 | Primer Plano Film Group | false | false |
| 34 | 30 | Luisa | $622 | -64% | 1 | -4 | $622 | $13,141 | 5 | Primer Plano Film Group | false | false |
| 35 | 25 | Knowing | $495 | -90.6% | 5 | -10 | $99 | $1,079,969 | 10 | Alfa Films | false | false |
| 36 | - | Haroldo Conti, homo viator | $484 | - | 2 | - | $242 | $484 | 2 | N/A | false | false |
| 37 | 15 | Chef's Special 2009 Re-release | $384 | -97.1% | 2 | -11 | $192 | $16,498 | 2 | Alfa Films | false | false |
| 38 | 33 | The Edge of Heaven | $293 | -55.7% | 1 | - | $293 | $155,387 | 12 | Alfa Films | false | false |
| 39 | 31 | Rumba | $275 | -84% | 2 | -4 | $137 | $67,755 | 10 | Distribution Company | false | false |
| 40 | 36 | Belle toujours 2008 Re-release | $196 | -34.9% | 2 | +1 | $98 | $65,716 | 9 | Impacto Cine | false | false |
| 41 | 34 | Slumdog Millionaire | $75 | -88.2% | 1 | -2 | $75 | $1,542,841 | 17 | Distribution Company | false | false |
| 42 | - | Bolt | $66 | - | 1 | - | $66 | $2,103,777 | 21 | Walt Disney Pictures | false | false |
| 43 | 41 | Vicky Cristina Barcelona | $53 | -34.6% | 1 | - | $53 | $772,079 | 18 | Pachamama Cine | false | false |
| 44 | 42 | Gomorrah | $43 | -27.1% | 1 | - | $43 | $253,920 | 13 | Alfa Films | false | false |
| 45 | - | The 100 Days That Didn't Shake the World | $18 | - | 1 | - | $18 | $806 | 2 | Primer Plano Film Group | false | false |
