| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Angels & Demons | $31,548 | -7.7% | 7 | -1 | $4,506 | $200,007 | 4 | Sony Pictures Releasing | false | false |
| 2 | 1 | Night at the Museum: Battle of the Smithsonian | $30,835 | -18.4% | 8 | - | $3,854 | $123,195 | 3 | 20th Century Fox International | false | false |
| 3 | - | Up | $16,677 | - | 2 | - | $8,338 | $16,677 | 1 | Walt Disney Pictures | true | false |
| 4 | 4 | X-Men Origins: Wolverine | $14,247 | -15.9% | 7 | - | $2,035 | $175,891 | 6 | 20th Century Fox International | false | false |
| 5 | 5 | State of Play | $11,969 | -1.3% | 6 | - | $1,994 | $52,422 | 3 | United International Pictures | false | false |
| 6 | 6 | Knowing | $9,503 | +22% | 4 | -1 | $2,375 | $246,624 | 7 | - | false | false |
| 7 | - | Coraline | $7,165 | - | 4 | - | $1,791 | $7,165 | 1 | United International Pictures | true | false |
| 8 | 7 | Duplicity | $5,782 | -22.5% | 7 | -1 | $826 | $78,774 | 5 | United International Pictures | false | false |
| 9 | 8 | The Uninvited | $3,440 | -10% | 6 | - | $573 | $64,349 | 6 | United International Pictures | false | false |
| 10 | 9 | Star Trek | $2,857 | -20.2% | 4 | -1 | $714 | $31,277 | 4 | United International Pictures | false | false |
| 11 | 10 | Fast & Furious | $1,003 | -28.8% | 5 | -1 | $200 | $242,476 | 9 | United International Pictures | false | false |
| 12 | 11 | Hannah Montana: The Movie | $893 | +45.2% | 2 | - | $446 | $67,284 | 9 | Walt Disney Pictures | false | false |
| 13 | 13 | 12 Rounds | $725 | +57.3% | 1 | - | $725 | $76,607 | 10 | 20th Century Fox International | false | false |
| 14 | 12 | Friday the 13th | $580 | -1.5% | 2 | - | $290 | $55,516 | 7 | United International Pictures | false | false |
| 15 | 14 | House | $268 | +165.3% | 1 | - | $268 | $130,953 | 12 | N/A | false | false |
| 16 | 17 | Paul Blart: Mall Cop | $187 | +503.2% | 1 | - | $187 | $77,263 | 8 | Sony Pictures Releasing | false | false |
| 17 | 15 | Push | $139 | +139.7% | 1 | - | $139 | $71,981 | 9 | - | false | false |
| 18 | 16 | It's Alive | $100 | +170.3% | 1 | - | $100 | $23,936 | 5 | N/A | false | false |
