| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Angels & Demons | $443,123 | - | 102 | - | $4,344 | $443,123 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Hannah Montana: The Movie | $22,511 | - | 12 | - | $1,875 | $29,712 | 1 | Walt Disney Pictures | true | false |
| 3 | 1 | X-Men Origins: Wolverine | $19,393 | -49.6% | 18 | -3 | $1,077 | $234,231 | 3 | 20th Century Fox International | false | false |
| 4 | 2 | The Unborn | $16,088 | -56.5% | 15 | - | $1,072 | $74,925 | 2 | United International Pictures | false | false |
| 5 | 5 | Knowing | $11,011 | -33.2% | 9 | -3 | $1,223 | $45,220 | 2 | N/A | false | false |
| 6 | 3 | Star Trek | $9,713 | -57.3% | 8 | -4 | $1,214 | $44,738 | 2 | United International Pictures | false | false |
| 7 | 4 | Paul Blart: Mall Cop | $7,774 | -57.4% | 7 | -7 | $1,110 | $226,929 | 6 | Sony Pictures Releasing | false | false |
| 8 | - | Doubt | $4,703 | - | 6 | - | $783 | $7,566 | 1 | Walt Disney Pictures | true | false |
| 9 | 8 | 17 Again | $1,394 | -79.3% | 4 | -6 | $348 | $81,266 | 4 | Warner Bros. | false | false |
| 10 | 7 | Race to Witch Mountain | $1,287 | -84.9% | 4 | -10 | $321 | $132,736 | 5 | Walt Disney Pictures | false | false |
| 11 | 9 | Milk | $1,066 | -82.8% | 2 | -6 | $533 | $9,530 | 2 | United International Pictures | false | false |
| 12 | 12 | Earth | $354 | -72.8% | 1 | -3 | $354 | $24,328 | 4 | Walt Disney Pictures | false | false |
| 13 | 6 | Underworld: Rise of the Lycans | $284 | -97.8% | 2 | -8 | $142 | $309,708 | 8 | Sony Pictures Releasing | false | false |
| 14 | 10 | Fast & Furious | $190 | -92.8% | 2 | -5 | $95 | $345,890 | 7 | United International Pictures | false | false |
| 15 | 14 | Monsters vs. Aliens | $154 | -68% | 1 | -1 | $154 | $196,497 | 7 | United International Pictures | false | false |
| 16 | 13 | The Flock | $62 | -93.2% | 1 | -3 | $62 | $10,098 | 3 | N/A | false | false |
