| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $44,253 | -25.9% | 8 | - | $5,531 | $114,005 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $38,528 | - | 8 | - | $4,816 | $38,528 | 1 | 20th Century Fox International | true | false |
| 3 | - | State of Play | $20,628 | - | 6 | - | $3,438 | $20,628 | 1 | United International Pictures | true | false |
| 4 | 2 | Knowing | $19,081 | -2.8% | 7 | -1 | $2,725 | $221,322 | 5 | - | false | false |
| 5 | 3 | X-Men Origins: Wolverine | $14,941 | -22.9% | 8 | - | $1,867 | $135,766 | 4 | 20th Century Fox International | false | false |
| 6 | 4 | Duplicity | $9,229 | -48.4% | 8 | - | $1,153 | $61,277 | 3 | United International Pictures | false | false |
| 7 | 5 | Star Trek | $7,033 | -53.6% | 5 | - | $1,406 | $23,061 | 2 | United International Pictures | false | false |
| 8 | 6 | The Uninvited | $2,886 | -68.9% | 5 | -3 | $577 | $55,820 | 4 | United International Pictures | false | false |
| 9 | 13 | House | $1,638 | -19.4% | 2 | -1 | $819 | $129,316 | 10 | N/A | false | false |
| 10 | 7 | Fast & Furious | $1,459 | -76.6% | 4 | -4 | $364 | $238,347 | 7 | United International Pictures | false | false |
| 11 | 8 | It's Alive | $1,365 | -65.5% | 2 | -2 | $682 | $23,172 | 3 | N/A | false | false |
| 12 | 9 | Hannah Montana: The Movie | $1,361 | -61.2% | 3 | -1 | $453 | $64,976 | 7 | Walt Disney Pictures | false | false |
| 13 | 11 | Push | $1,266 | -57.1% | 3 | -2 | $422 | $71,074 | 7 | - | false | false |
| 14 | 14 | The Curious Case of Benjamin Button | $1,006 | -43.2% | 2 | -1 | $503 | $385,605 | 14 | Warner Bros. | false | false |
| 15 | 12 | Paul Blart: Mall Cop | $1,003 | -63.4% | 2 | -2 | $501 | $76,447 | 6 | Sony Pictures Releasing | false | false |
| 16 | 10 | Friday the 13th | $877 | -73.8% | 3 | -4 | $292 | $53,679 | 5 | United International Pictures | false | false |
| 17 | 16 | 12 Rounds | $627 | -37.9% | 1 | -2 | $627 | $74,777 | 8 | 20th Century Fox International | false | false |
| 18 | 18 | The Unborn | $207 | -76.3% | 1 | -2 | $207 | $110,822 | 9 | United International Pictures | false | false |
| 19 | 17 | Crossing Over | $67 | -92.3% | 1 | -1 | $67 | $46,417 | 6 | N/A | false | false |
