| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 17 Again | $260,319 | - | 55 | - | $4,733 | $260,319 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Fast & Furious | $206,358 | -60.7% | 63 | - | $3,275 | $999,406 | 2 | United International Pictures | false | false |
| 3 | 2 | Monsters vs. Aliens | $97,931 | -48.7% | 85 | -12 | $1,152 | $952,941 | 3 | United International Pictures | false | false |
| 4 | 4 | Marley & Me | $55,965 | -46.4% | 65 | - | $861 | $1,124,661 | 5 | NuMetro Distribution | false | false |
| 5 | - | Hotel for Dogs | $52,650 | - | 43 | - | $1,224 | $52,650 | 1 | United International Pictures | true | false |
| 6 | 5 | Slumdog Millionaire | $37,861 | -32.6% | 20 | +1 | $1,893 | $861,145 | 7 | Ster-Kinekor Pictures | false | false |
| 7 | 3 | Dragonball Evolution | $31,177 | -71.1% | 35 | - | $890 | $190,778 | 2 | 20th Century Fox International | false | false |
| 8 | 6 | Race to Witch Mountain | $27,309 | -48.1% | 50 | -3 | $546 | $440,113 | 4 | Ster-Kinekor Pictures | false | false |
| 9 | 7 | Confessions of a Shopaholic | $25,570 | -50.7% | 43 | -7 | $594 | $611,187 | 6 | Ster-Kinekor Pictures | false | false |
| 10 | 9 | The Reader | $19,942 | -31% | 10 | - | $1,994 | $163,355 | 4 | Ster-Kinekor Pictures | false | false |
| 11 | 11 | Gran Torino | $17,037 | -36.4% | 23 | -7 | $740 | $197,406 | 4 | NuMetro Distribution | false | false |
| 12 | 8 | Tornado 2009 Re-release | $16,936 | -55.3% | 33 | -9 | $513 | $78,941 | 2 | Ster-Kinekor Pictures | false | false |
| 13 | 10 | Underworld: Rise of the Lycans | $13,856 | -49.2% | 26 | -7 | $532 | $237,737 | 4 | Ster-Kinekor Pictures | false | false |
| 14 | 12 | 12 Rounds | $11,058 | -53.7% | 24 | - | $460 | $107,413 | 3 | NuMetro Distribution | false | false |
| 15 | 13 | He's Just Not That Into You | $10,411 | -49.6% | 27 | -9 | $385 | $903,396 | 10 | NuMetro Distribution | false | false |
| 16 | 14 | The Curious Case of Benjamin Button | $8,094 | -45% | 18 | -4 | $449 | $642,362 | 8 | NuMetro Distribution | false | false |
| 17 | - | The Spirit | $6,914 | - | 10 | - | $691 | $6,914 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | - | Paul Blart: Mall Cop | $5,293 | - | 11 | - | $481 | $170,747 | 6 | Ster-Kinekor Pictures | false | false |
| 19 | 20 | Defiance | $4,633 | -17.9% | 7 | -1 | $661 | $57,507 | 5 | United International Pictures | false | false |
| 20 | - | 8 x 10 Tasveer | $4,047 | - | 4 | - | $1,011 | $4,047 | 1 | NuMetro Distribution | true | false |
| 21 | 21 | Watchmen | $2,767 | -48.8% | 7 | -2 | $395 | $420,090 | 7 | Ster-Kinekor Pictures | false | false |
| 22 | 18 | Friday the 13th | $2,582 | -55.7% | 5 | -1 | $516 | $71,341 | 6 | United International Pictures | false | false |
| 23 | 22 | The Baader Meinhof Complex | $2,537 | -30.4% | 5 | -3 | $507 | $17,854 | 3 | United International Pictures | false | false |
| 24 | 23 | Changeling | $1,790 | -12% | 6 | -2 | $298 | $210,663 | 9 | United International Pictures | false | false |
