| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Fast & Furious | $7,235,550 | - | 364 | - | $19,877 | $7,235,550 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Monsters vs. Aliens | $4,150,701 | -35.6% | 520 | - | $7,982 | $16,927,179 | 2 | Paramount Pictures International | false | false |
| 3 | - | 17 Again | $3,764,151 | - | 407 | - | $9,248 | $3,764,151 | 1 | Entertainment Film Distributors | true | false |
| 4 | 2 | The Boat That Rocked | $1,417,211 | -47.1% | 460 | -2 | $3,080 | $5,807,852 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | Knowing | $909,256 | -36.7% | 373 | -18 | $2,437 | $8,226,059 | 3 | Entertainment One | false | false |
| 6 | - | Race to Witch Mountain | $853,286 | - | 409 | - | $2,086 | $853,286 | 1 | Walt Disney Pictures | true | false |
| 7 | 4 | Marley & Me | $690,155 | -43.4% | 402 | -31 | $1,716 | $20,752,711 | 5 | 20th Century Fox International | false | false |
| 8 | - | Dragonball Evolution | $640,385 | - | 319 | - | $2,007 | $640,385 | 1 | 20th Century Fox International | true | false |
| 9 | 5 | The Haunting in Connecticut | $558,251 | -50% | 281 | -33 | $1,986 | $5,075,716 | 3 | Entertainment Film Distributors | false | false |
| 10 | 6 | Paul Blart: Mall Cop | $343,475 | -60.1% | 341 | -39 | $1,007 | $6,949,064 | 4 | Sony Pictures Releasing | false | false |
| 11 | - | Let the Right One In | $329,062 | - | 68 | - | $4,839 | $329,062 | 1 | Momentum Pictures | true | false |
| 12 | 7 | The Damned United | $212,872 | -55.2% | 176 | -64 | $1,209 | $2,671,162 | 3 | Sony Pictures Releasing | false | false |
| 13 | 9 | Gran Torino | $159,070 | -43.8% | 119 | -89 | $1,336 | $11,715,640 | 8 | Warner Bros. | false | false |
| 14 | - | Fifty Dead Men Walking | $145,980 | - | 76 | - | $1,920 | $145,980 | 1 | - | true | false |
| 15 | 8 | Duplicity | $143,261 | -63.1% | 92 | -152 | $1,557 | $4,008,802 | 4 | Universal Pictures International (UPI) | false | false |
| 16 | 11 | Slumdog Millionaire | $82,876 | -45% | 55 | -80 | $1,506 | $46,162,488 | 14 | Pathé | false | false |
| 17 | 10 | Watchmen | $78,075 | -57.7% | 50 | -83 | $1,561 | $12,897,239 | 6 | Paramount Pictures International | false | false |
| 18 | 17 | Hotel for Dogs | $58,706 | +3.1% | 162 | -69 | $362 | $10,236,464 | 9 | Paramount Pictures International | false | false |
| 19 | 13 | The Young Victoria | $45,808 | -61.8% | 49 | -137 | $934 | $6,892,240 | 6 | Momentum Pictures | false | false |
| 20 | 22 | The Class | $33,370 | -11.5% | 16 | -1 | $2,085 | $1,149,990 | 7 | Artificial Eye | false | false |
| 21 | 15 | Bolt | $30,030 | -53.5% | 97 | -166 | $309 | $26,241,654 | 9 | Walt Disney Pictures | false | false |
| 22 | 23 | Il Divo | $29,990 | -19.4% | 12 | -1 | $2,499 | $421,740 | 4 | Artificial Eye | false | false |
| 23 | - | The 400 Blows 2009 Re-release | $28,458 | - | 9 | - | $3,162 | $28,458 | 1 | British Film Institute (BFI) | true | false |
| 24 | 16 | 8 x 10 Tasveer | $25,171 | -59.4% | 11 | -21 | $2,288 | $123,566 | 2 | - | false | false |
| 25 | 53 | The Secret of Moonacre | $20,521 | +662.3% | 80 | +62 | $256 | $1,318,977 | 10 | Warner Bros. | false | false |
| 26 | - | Tera Mera Ki Rishta | $20,457 | - | 8 | - | $2,557 | $20,457 | 1 | Eros Worldwide | true | false |
| 27 | 14 | Two Lovers | $20,218 | -71.9% | 16 | -24 | $1,263 | $351,316 | 3 | Lionsgate | false | false |
| 28 | 29 | The Reader | $19,231 | +0.2% | 15 | +3 | $1,282 | $8,377,356 | 15 | Entertainment Film Distributors | false | false |
| 29 | 50 | Madagascar: Escape 2 Africa | $19,058 | +557.9% | 77 | +57 | $247 | $34,101,738 | 19 | Paramount Pictures International | false | false |
| 30 | 18 | Ayan | $18,579 | -66.8% | 11 | - | $1,689 | $98,654 | 2 | Ayngaran International | false | false |
| 31 | 27 | A Summer in Genoa | $17,042 | -34% | 9 | -4 | $1,893 | $127,004 | 3 | - | false | false |
| 32 | 47 | Under the Sea 3D | $15,232 | +349.6% | 1 | - | $15,232 | $223,951 | 9 | IMAX | false | false |
| 33 | 21 | Waveriders | $12,961 | -66% | 14 | -1 | $925 | $82,469 | 2 | Element Films | false | false |
| 34 | 25 | Religulous | $11,859 | -57.3% | 8 | -3 | $1,482 | $62,557 | 2 | Momentum Pictures | false | false |
| 35 | 28 | Vicky Cristina Barcelona | $11,649 | -50.2% | 9 | -5 | $1,294 | $3,835,997 | 10 | Optimum Releasing | false | false |
| 36 | 32 | The Tale of Despereaux | $11,608 | +9.3% | 71 | -6 | $163 | $3,716,603 | 17 | Universal Pictures International (UPI) | false | false |
| 37 | - | Tony Manero | $11,057 | - | 7 | - | $1,579 | $11,057 | 1 | - | true | false |
| 38 | 20 | Bronson | $10,929 | -75.4% | 21 | -36 | $520 | $1,298,001 | 5 | Vertigo Films | false | false |
| 39 | 12 | Vampire Killers | $10,181 | -92.4% | 49 | -165 | $207 | $2,450,829 | 4 | Momentum Pictures | false | false |
| 40 | 42 | Milk | $8,544 | +75.4% | 4 | - | $2,136 | $2,074,012 | 12 | Momentum Pictures | false | false |
| 41 | 34 | He's Just Not That Into You | $7,462 | -7.1% | 5 | -1 | $1,492 | $13,898,291 | 10 | Entertainment Film Distributors | false | false |
| 42 | 31 | Modern Life | $6,731 | -41% | 4 | -2 | $1,682 | $24,403 | 2 | Soda Pictures | false | false |
| 43 | 45 | My Bloody Valentine | $6,304 | +54.9% | 17 | +1 | $370 | $10,126,125 | 13 | Lionsgate | false | false |
| 44 | 24 | Confessions of a Shopaholic | $5,891 | -79.2% | 19 | -51 | $310 | $12,098,508 | 8 | Walt Disney Pictures | false | false |
| 45 | 33 | Revolutionary Road | $5,382 | -49.1% | 5 | -4 | $1,076 | $5,065,300 | 11 | Paramount Pictures International | false | false |
| 46 | 44 | Anvil: The Story of Anvil | $3,536 | -19.5% | 4 | -3 | $884 | $210,774 | 8 | The Works UK Distribution | false | false |
| 47 | 40 | Che: Part Two | $3,121 | -41.9% | 7 | - | $445 | $407,431 | 8 | Optimum Releasing | false | false |
| 48 | 51 | Che: Part One | $3,030 | +8.1% | 7 | +4 | $432 | $1,956,459 | 15 | Optimum Releasing | false | false |
| 49 | - | Bottle Shock | $2,706 | - | 4 | - | $676 | $9,638 | 4 | Paramount Pictures International | false | false |
| 50 | 41 | The Age of Stupid | $2,472 | -54% | 3 | -3 | $824 | $239,579 | 4 | Periscoop Film | false | false |
| 51 | 36 | Doubt | $2,227 | -71.8% | 6 | -4 | $371 | $1,891,522 | 10 | Walt Disney Pictures | false | false |
| 52 | 43 | Wendy and Lucy | $2,105 | -54.5% | 4 | -2 | $526 | $139,519 | 6 | Soda Pictures | false | false |
| 53 | 26 | Traitor | $2,090 | -92.4% | 7 | -48 | $298 | $234,570 | 3 | Momentum Pictures | false | false |
| 54 | 37 | In the City of Sylvia | $1,905 | -71.1% | 5 | -2 | $381 | $82,513 | 5 | Axiom Films | false | false |
| 55 | - | The Burning Plain | $1,130 | - | 2 | - | $565 | $15,814 | 5 | Paramount Pictures International | false | false |
| 56 | 46 | Valkyrie | $1,047 | -73.1% | 10 | +6 | $104 | $9,552,207 | 12 | 20th Century Fox International | false | false |
| 57 | 69 | Hush | $1,000 | +104.9% | 3 | -2 | $333 | $135,087 | 5 | Optimum Releasing | false | false |
| 58 | 65 | Cherry Blossoms | $987 | +20.1% | 1 | - | $987 | $4,670 | 2 | Periscoop Film | false | false |
| 59 | 55 | The Wrestler | $960 | -55.8% | 1 | -1 | $960 | $3,721,859 | 13 | Optimum Releasing | false | false |
| 60 | 58 | Flame & Citron | $909 | -40.4% | 1 | -3 | $909 | $57,871 | 6 | - | false | false |
| 61 | 70 | Waltz with Bashir | $875 | +109.8% | 1 | - | $875 | $1,029,187 | 21 | Artificial Eye | false | false |
| 62 | 48 | The International | $740 | -76.3% | 1 | -2 | $740 | $4,458,452 | 7 | Sony Pictures Releasing | false | false |
| 63 | 35 | The Curious Case of Benjamin Button | $705 | -91.1% | 2 | -13 | $352 | $13,305,272 | 10 | Warner Bros. | false | false |
| 64 | 57 | The Secret of Kells | $694 | -56.2% | 6 | -6 | $115 | $93,983 | 6 | Walt Disney Pictures | false | false |
| 65 | 68 | Afghan Star | $633 | +7.3% | 1 | - | $633 | $9,704 | 3 | - | false | false |
| 66 | 72 | Twilight | $573 | +55.7% | 5 | +2 | $114 | $16,282,193 | 17 | Contender Entertainment Group | false | false |
| 67 | 67 | Three Monkeys | $123 | -80.4% | 2 | -1 | $61 | $118,992 | 9 | New Wave Films | false | false |
| 68 | 61 | Frost/Nixon | $103 | -92.1% | 1 | -3 | $103 | $2,774,746 | 12 | Universal Pictures International (UPI) | false | false |
| 69 | 75 | Defiance | $29 | -3.3% | 1 | - | $29 | $5,584,810 | 14 | Momentum Pictures | false | false |
| 70 | 74 | Notorious | $29 | -75.8% | 1 | - | $29 | - | 9 | 20th Century Fox International | false | false |
| 71 | 63 | Franklyn | $29 | -97% | 1 | -1 | $29 | $16,691 | 7 | Entertainment One | false | false |
| 72 | 59 | North Face | $29 | -97.9% | 1 | -2 | $29 | $78,021 | 18 | - | false | false |
| 73 | 66 | I've Loved You So Long | $29 | -96% | 1 | - | $29 | $1,796,602 | 29 | Lionsgate | false | false |
| 74 | 73 | Gomorrah | $29 | -83.6% | 1 | - | $29 | $1,386,619 | 27 | Optimum Releasing | false | false |
