| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Fast & Furious | $3,614,786 | - | 333 | - | $10,855 | $3,614,786 | 1 | United International Pictures | true | false |
| 2 | - | Monsters vs. Aliens | $2,762,497 | - | 538 | - | $5,134 | $2,762,497 | 1 | Paramount Pictures International | true | false |
| 3 | 1 | Sex, Party & Lies | $1,104,229 | -51.8% | 240 | +26 | $4,600 | $3,986,461 | 2 | Sony Pictures Releasing | false | false |
| 4 | 2 | Gran Torino | $1,026,556 | -28.4% | 263 | - | $3,903 | $11,929,765 | 5 | Warner Bros. | false | false |
| 5 | - | Deception | $802,929 | - | 235 | - | $3,416 | $802,929 | 1 | TriPictures | true | false |
| 6 | 3 | Marley & Me | $392,234 | -52.3% | 293 | -11 | $1,338 | $2,917,790 | 3 | 20th Century Fox International | false | false |
| 7 | 7 | Slumdog Millionaire | $391,727 | -34.5% | 220 | -32 | $1,780 | $12,518,453 | 8 | Filmax | false | false |
| 8 | - | The Duchess | $391,101 | - | 160 | - | $2,444 | $391,101 | 1 | Vértigo Films | true | false |
| 9 | 4 | Confessions of a Shopaholic | $370,971 | -48.6% | 270 | - | $1,373 | $1,289,265 | 2 | Walt Disney Pictures | false | false |
| 10 | 5 | Duplicity | $312,802 | -54.3% | 261 | -39 | $1,198 | $2,785,292 | 3 | United International Pictures | false | false |
| 11 | 6 | Bedtime Stories | $216,221 | -65.8% | 265 | -68 | $815 | $5,880,147 | 5 | Walt Disney Pictures | false | false |
| 12 | 9 | Hotel for Dogs | $141,090 | -66% | 205 | -9 | $688 | $1,772,782 | 4 | Paramount Pictures International | false | false |
| 13 | - | Black Listed | $109,944 | - | 63 | - | $1,745 | $109,944 | 1 | Filmax | true | false |
| 14 | 10 | Underworld: Rise of the Lycans | $104,207 | -72.5% | 163 | -124 | $639 | $3,422,180 | 4 | Sony Pictures Releasing | false | false |
| 15 | 8 | Street Fighter: The Legend of Chun-Li | $100,189 | -80.6% | 258 | -16 | $388 | $751,584 | 2 | DeAPlaneta | false | false |
| 16 | 15 | The Visitor | $100,026 | -22.5% | 44 | -6 | $2,273 | $694,866 | 4 | Karma Films | false | false |
| 17 | 12 | The Reader | $96,849 | -44.2% | 75 | -62 | $1,291 | $5,883,022 | 8 | On Pictures | false | false |
| 18 | 11 | Traitor | $40,282 | -80.9% | 100 | -15 | $402 | $325,337 | 2 | United International Pictures | false | false |
| 19 | 16 | The Curious Case of Benjamin Button | $37,236 | -67.2% | 50 | -87 | $744 | $16,105,965 | 9 | Warner Bros. | false | false |
| 20 | 13 | Watchmen | $36,570 | -75.1% | 55 | -115 | $664 | $4,119,758 | 5 | Paramount Pictures International | false | false |
| 21 | 18 | The Burning Plain | $35,063 | -63.4% | 40 | -42 | $876 | $854,769 | 4 | United International Pictures | false | false |
| 22 | 14 | The Code | $34,308 | -76.5% | 62 | -91 | $553 | $2,183,209 | 5 | DeAPlaneta | false | false |
| 23 | 21 | The Secret Life of Bees | $28,652 | -58.9% | 41 | -5 | $698 | $129,757 | 2 | 20th Century Fox International | false | false |
| 24 | 23 | Return to Hansala | $25,193 | -51.1% | 38 | -1 | $662 | $102,823 | 2 | Wanda Visión S.A. | false | false |
| 25 | 17 | The Pink Panther 2 | $25,005 | -74% | 79 | -72 | $316 | $3,766,995 | 6 | Sony Pictures Releasing | false | false |
| 26 | 24 | A Christmas Tale | $24,118 | -8.7% | 8 | - | $3,014 | $64,535 | 2 | Alta Films | false | false |
| 27 | 19 | Blindness | $23,611 | -72.7% | 28 | -54 | $843 | $762,798 | 4 | Notro Films | false | false |
| 28 | - | The Good Life | $18,678 | - | 9 | - | $2,075 | $18,678 | 1 | Alta Films | true | false |
| 29 | 27 | Cherry Blossoms | $16,674 | -22.7% | 18 | -3 | $926 | $250,551 | 5 | Wanda Visión S.A. | false | false |
| 30 | 22 | Paul Blart: Mall Cop | $15,852 | -69.9% | 27 | -3 | $587 | $79,261 | 2 | Sony Pictures Releasing | false | false |
| 31 | - | The Hands 2009 Re-release | $15,240 | - | 12 | - | $1,270 | $15,240 | 1 | N/A | true | false |
| 32 | 25 | Cloud 9 | $13,075 | -46.2% | 13 | -10 | $1,005 | $115,525 | 3 | Baditri | false | false |
| 33 | 20 | Beverly Hills Chihuahua | $11,857 | -83.5% | 73 | -64 | $162 | $7,847,107 | 9 | Walt Disney Pictures | false | false |
| 34 | 31 | El libro de las aguas | $10,799 | +9.6% | 5 | -1 | $2,159 | $197,366 | 21 | Independent Films | false | false |
| 35 | 28 | Welcome to the Sticks | $9,832 | -48.4% | 11 | -5 | $893 | $4,560,638 | 13 | Wanda Visión S.A. | false | false |
| 36 | 32 | Revolutionary Road | $9,270 | -1.1% | 24 | +13 | $386 | $5,534,677 | 11 | Paramount Pictures International | false | false |
| 37 | 26 | Doubt | $9,171 | -60.4% | 17 | -24 | $539 | $3,459,995 | 10 | Walt Disney Pictures | false | false |
| 38 | 30 | The Class | $6,780 | -41.3% | 9 | -5 | $753 | $1,723,758 | 12 | Golem Distribución | false | false |
| 39 | 34 | Let it Rain | $5,689 | -34.5% | 7 | -7 | $812 | $234,763 | 6 | - | false | false |
| 40 | 39 | Waltz with Bashir | $4,485 | -29.2% | 4 | -2 | $1,121 | $210,439 | 7 | Golem Distribución | false | false |
| 41 | 36 | Lost in Galicia | $4,056 | -48.6% | 6 | -6 | $676 | $112,267 | 4 | Walt Disney Pictures | false | false |
| 42 | 37 | Atanarjuat: The Fast Runner 2009 Re-release | $3,943 | -44.1% | 5 | - | $788 | $14,441 | 2 | Karma Films | false | false |
| 43 | 33 | Captain Abu Raed | $3,357 | -62% | 7 | -9 | $479 | $47,149 | 3 | Golem Distribución | false | false |
| 44 | 44 | The Wrestler | $2,191 | -49.5% | 5 | -11 | $438 | $1,076,675 | 7 | United International Pictures | false | false |
| 45 | 40 | Che: Part Two | $1,981 | -67.8% | 5 | -15 | $396 | $1,084,771 | 6 | 20th Century Fox International | false | false |
| 46 | 41 | The Baader Meinhof Complex | $1,922 | -65.4% | 4 | -10 | $480 | $115,352 | 4 | - | false | false |
| 47 | 38 | Push | $1,695 | -75.7% | 6 | -15 | $282 | $2,878,448 | 7 | - | false | false |
| 48 | 29 | Animal Channel | $1,505 | -89.9% | 19 | -6 | $79 | $18,684 | 2 | Barton Films | false | false |
| 49 | 51 | The Milk of Sorrow | $1,313 | -15.5% | 4 | -2 | $328 | $227,946 | 8 | Wanda Visión S.A. | false | false |
| 50 | 42 | In the Name of the King: A Dungeon Siege Tale | $676 | -86.5% | 5 | -19 | $135 | $1,224,282 | 6 | New World Pictures | false | false |
| 51 | 61 | The Hanged Man | $635 | +155% | 6 | - | $105 | $470,146 | 10 | Sony Pictures Releasing | false | false |
| 52 | 35 | Seven Pounds | $538 | -93.3% | 6 | -15 | $89 | $13,455,463 | 12 | Sony Pictures Releasing | false | false |
| 53 | 64 | The Equation of Love and Death | $476 | +434.8% | 2 | +1 | $238 | $5,584 | 4 | Barton Films | false | false |
| 54 | - | Noise | $421 | - | 2 | - | $210 | $421 | 1 | - | true | false |
| 55 | 52 | Milk | $395 | -71.2% | 2 | -3 | $197 | $1,784,847 | 13 | United International Pictures | false | false |
| 56 | 59 | Valkyrie | $340 | -9.1% | 2 | -2 | $170 | $7,963,996 | 10 | 20th Century Fox International | false | false |
| 57 | 47 | Bolt | $318 | -89% | 3 | -9 | $106 | $10,972,214 | 18 | Walt Disney Pictures | false | false |
| 58 | 49 | El Zorro de San Adrian | $166 | -91% | 1 | -4 | $166 | $129,125 | 9 | Barton Films | false | false |
| 59 | 65 | Cadillac Records | $95 | +20.3% | 1 | - | $95 | $39,492 | 7 | Sony Pictures Releasing | false | false |
| 60 | 45 | Ben X | $93 | -97.7% | 2 | -14 | $46 | $5,841 | 2 | Karma Films | false | false |
| 61 | 48 | The Tale of Despereaux | $90 | -95.6% | 2 | -3 | $45 | $3,948,152 | 16 | Universal Pictures International (UPI) | false | false |
| 62 | 60 | Nick and Norah's Infinite Playlist | $83 | -73% | 1 | - | $83 | $25,802 | 8 | Sony Pictures Releasing | false | false |
| 63 | 66 | Mediterranean Food | $64 | +146.2% | 1 | - | $64 | $863,681 | 9 | Alta Films | false | false |
