| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Sex, Party & Lies | $2,289,095 | - | 214 | - | $10,696 | $2,289,095 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Gran Torino | $1,433,829 | -7.8% | 263 | - | $5,451 | $10,001,188 | 4 | Warner Bros. | false | false |
| 3 | 2 | Marley & Me | $823,035 | -19.3% | 304 | +1 | $2,707 | $2,272,528 | 2 | 20th Century Fox International | false | false |
| 4 | - | Confessions of a Shopaholic | $721,227 | - | 270 | - | $2,671 | $724,657 | 1 | Walt Disney Pictures | true | false |
| 5 | 3 | Duplicity | $683,922 | -31.1% | 300 | -1 | $2,279 | $2,202,075 | 2 | United International Pictures | false | false |
| 6 | 4 | Bedtime Stories | $631,532 | -16.5% | 333 | -47 | $1,896 | $5,313,251 | 4 | Walt Disney Pictures | false | false |
| 7 | 6 | Slumdog Millionaire | $597,642 | -12.5% | 252 | - | $2,371 | $11,361,995 | 7 | Filmax | false | false |
| 8 | - | Street Fighter: The Legend of Chun-Li | $515,195 | - | 274 | - | $1,880 | $515,195 | 1 | DeAPlaneta | true | false |
| 9 | 7 | Hotel for Dogs | $415,524 | +0.7% | 214 | -6 | $1,941 | $1,515,960 | 3 | Paramount Pictures International | false | false |
| 10 | 5 | Underworld: Rise of the Lycans | $378,674 | -47.8% | 287 | -10 | $1,319 | $3,215,398 | 3 | Sony Pictures Releasing | false | false |
| 11 | - | Traitor | $210,558 | - | 115 | - | $1,830 | $210,558 | 1 | United International Pictures | true | false |
| 12 | 10 | The Reader | $173,518 | -25.4% | 137 | -55 | $1,266 | $5,437,349 | 7 | On Pictures | false | false |
| 13 | 8 | Watchmen | $146,742 | -56.5% | 170 | -191 | $863 | $3,823,462 | 4 | Paramount Pictures International | false | false |
| 14 | 9 | The Code | $146,147 | -43.5% | 153 | -65 | $955 | $2,008,887 | 4 | DeAPlaneta | false | false |
| 15 | 15 | The Visitor | $129,141 | +5.9% | 50 | -2 | $2,582 | $513,614 | 3 | Karma Films | false | false |
| 16 | 11 | The Curious Case of Benjamin Button | $113,528 | -43.2% | 137 | -79 | $828 | $15,229,669 | 8 | Warner Bros. | false | false |
| 17 | 12 | The Pink Panther 2 | $96,236 | -42.5% | 151 | -128 | $637 | $3,727,920 | 5 | Sony Pictures Releasing | false | false |
| 18 | 14 | The Burning Plain | $95,699 | -39.4% | 82 | -19 | $1,167 | $746,111 | 3 | United International Pictures | false | false |
| 19 | 13 | Blindness | $86,346 | -46.9% | 82 | -37 | $1,053 | $678,416 | 3 | Notro Films | false | false |
| 20 | 16 | Beverly Hills Chihuahua | $71,721 | -27.3% | 137 | -73 | $523 | $7,432,662 | 8 | Walt Disney Pictures | false | false |
| 21 | - | The Secret Life of Bees | $69,681 | - | 46 | - | $1,514 | $69,681 | 1 | 20th Century Fox International | true | false |
| 22 | - | Paul Blart: Mall Cop | $52,615 | - | 30 | - | $1,753 | $52,615 | 1 | Sony Pictures Releasing | true | false |
| 23 | - | Return to Hansala | $51,565 | - | 39 | - | $1,322 | $51,565 | 1 | Wanda Visión S.A. | true | false |
| 24 | - | A Christmas Tale | $26,404 | - | 8 | - | $3,300 | $26,404 | 1 | Alta Films | true | false |
| 25 | 19 | Cloud 9 | $24,289 | -23.7% | 23 | -4 | $1,056 | $85,579 | 2 | Baditri | false | false |
| 26 | 17 | Doubt | $23,140 | -42.6% | 41 | -33 | $564 | $3,267,905 | 9 | Walt Disney Pictures | false | false |
| 27 | 20 | Cherry Blossoms | $21,561 | -18.5% | 21 | -9 | $1,026 | $212,308 | 4 | Wanda Visión S.A. | false | false |
| 28 | 21 | Welcome to the Sticks | $19,046 | -18.2% | 16 | -8 | $1,190 | $4,315,869 | 12 | Wanda Visión S.A. | false | false |
| 29 | - | Animal Channel | $14,963 | - | 25 | - | $598 | $14,963 | 1 | Barton Films | true | false |
| 30 | 25 | The Class | $11,545 | -35.8% | 14 | -8 | $824 | $1,625,364 | 11 | Golem Distribución | false | false |
| 31 | 31 | El libro de las aguas | $9,855 | +2% | 6 | +1 | $1,642 | $177,118 | 20 | Independent Films | false | false |
| 32 | 29 | Revolutionary Road | $9,374 | -17.8% | 11 | -13 | $852 | $5,239,833 | 10 | Paramount Pictures International | false | false |
| 33 | 28 | Captain Abu Raed | $8,832 | -43.1% | 16 | -3 | $552 | $37,880 | 2 | Golem Distribución | false | false |
| 34 | 30 | Let it Rain | $8,684 | -20.1% | 14 | -1 | $620 | $213,703 | 5 | - | false | false |
| 35 | 24 | Seven Pounds | $8,016 | -56.2% | 21 | -28 | $381 | $13,449,298 | 11 | Sony Pictures Releasing | false | false |
| 36 | 26 | Lost in Galicia | $7,893 | -56% | 12 | -34 | $657 | $100,528 | 3 | Walt Disney Pictures | false | false |
| 37 | - | Atanarjuat: The Fast Runner 2009 Re-release | $7,055 | - | 5 | - | $1,411 | $7,055 | 1 | Karma Films | true | false |
| 38 | 18 | Push | $6,976 | -78.2% | 21 | -46 | $332 | $2,724,121 | 6 | - | false | false |
| 39 | 37 | Waltz with Bashir | $6,333 | +55.1% | 6 | -3 | $1,055 | $192,381 | 6 | Golem Distribución | false | false |
| 40 | 23 | Che: Part Two | $6,148 | -72.7% | 20 | -44 | $307 | $1,025,689 | 5 | 20th Century Fox International | false | false |
| 41 | 27 | The Baader Meinhof Complex | $5,561 | -68.7% | 14 | -47 | $397 | $104,696 | 3 | - | false | false |
| 42 | 22 | In the Name of the King: A Dungeon Siege Tale | $4,998 | -78% | 24 | -40 | $208 | $1,159,764 | 5 | New World Pictures | false | false |
| 43 | 52 | Madagascar: Escape 2 Africa | $4,728 | +667.5% | 8 | +2 | $591 | $19,610,109 | 18 | Paramount Pictures International | false | false |
| 44 | 32 | The Wrestler | $4,339 | -53% | 16 | -10 | $271 | $1,018,406 | 6 | United International Pictures | false | false |
| 45 | - | Ben X | $4,085 | - | 16 | - | $255 | $4,085 | 1 | Karma Films | true | false |
| 46 | 36 | The Missing Lynx | $3,776 | -18.2% | 9 | -9 | $419 | $1,445,936 | 14 | - | false | false |
| 47 | 42 | Bolt | $2,899 | +62.7% | 12 | -3 | $241 | $10,416,171 | 17 | Walt Disney Pictures | false | false |
| 48 | 44 | The Tale of Despereaux | $2,043 | +42.3% | 5 | -1 | $408 | $3,748,093 | 15 | Universal Pictures International (UPI) | false | false |
| 49 | 39 | El Zorro de San Adrian | $1,851 | -20.2% | 5 | -2 | $370 | $122,367 | 8 | Barton Films | false | false |
| 50 | 34 | Friday the 13th | $1,791 | -69% | 7 | -17 | $255 | $1,811,189 | 7 | Paramount Pictures International | false | false |
| 51 | 35 | The Milk of Sorrow | $1,553 | -70.3% | 6 | -4 | $258 | $214,630 | 7 | Wanda Visión S.A. | false | false |
| 52 | 38 | Milk | $1,371 | -59.1% | 5 | -2 | $274 | $1,693,566 | 12 | United International Pictures | false | false |
| 53 | 48 | El ratón Pérez 2 | $1,075 | +42.4% | 3 | -1 | $358 | $1,120,819 | 16 | Filmax | false | false |
| 54 | 45 | Frost/Nixon | $987 | -25.1% | 4 | -1 | $246 | $439,038 | 8 | Universal Pictures International (UPI) | false | false |
| 55 | 41 | The Way | $966 | -47.3% | 1 | -2 | $966 | $2,150,273 | 24 | Alta Films | false | false |
| 56 | 53 | Julia | $633 | +5.7% | 6 | - | $105 | $72,133 | 5 | Vértigo Films | false | false |
| 57 | 40 | The Wave | $526 | -74.7% | 1 | -4 | $526 | $1,683,775 | 18 | - | false | false |
| 58 | 55 | Easy Virtue | $459 | +14.8% | 1 | -1 | $459 | $1,870,010 | 13 | DeAPlaneta | false | false |
| 59 | 33 | Valkyrie | $374 | -93.7% | 4 | -18 | $93 | $7,559,892 | 9 | 20th Century Fox International | false | false |
| 60 | - | Nick and Norah's Infinite Playlist | $307 | - | 1 | - | $307 | $25,580 | 7 | Sony Pictures Releasing | false | false |
| 61 | 47 | The Hanged Man | $249 | -76% | 6 | -6 | $41 | $461,395 | 9 | Sony Pictures Releasing | false | false |
| 62 | 49 | Ghost Town | $203 | -72.9% | 2 | -4 | $101 | $111,872 | 5 | Paramount Pictures International | false | false |
| 63 | 43 | The Broken | $97 | -93.5% | 1 | -3 | $97 | $19,235 | 5 | Independent Films | false | false |
| 64 | 51 | The Equation of Love and Death | $89 | -86.5% | 1 | -1 | $89 | $4,787 | 3 | Barton Films | false | false |
| 65 | 62 | Cadillac Records | $79 | -32.5% | 1 | - | $79 | $39,392 | 6 | Sony Pictures Releasing | false | false |
| 66 | 56 | Mediterranean Food | $26 | -91.8% | 1 | -2 | $26 | $819,820 | 8 | Alta Films | false | false |
