| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Marley & Me | $26,327 | -39.6% | 8 | - | $3,290 | $102,472 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | - | Duplicity | $22,667 | - | 7 | - | $3,238 | $22,667 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | Bolt | $20,936 | -23.1% | 9 | - | $2,326 | $281,069 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | - | Hotel for Dogs | $19,422 | - | 8 | - | $2,427 | $19,422 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | 4 | Slumdog Millionaire | $16,409 | -15.5% | 4 | - | $4,102 | $251,678 | 6 | ACME | false | false |
| 6 | 3 | Watchmen | $10,268 | -51.5% | 6 | - | $1,711 | $41,250 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | The Unborn | $6,671 | -46.9% | 5 | -2 | $1,334 | $83,141 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | He's Just Not That Into You | $5,090 | -16.1% | 5 | -1 | $1,018 | $145,121 | 5 | - | false | false |
| 9 | 6 | The Crimson Wing: Mystery of the Flamingos | $4,373 | -31.7% | 4 | - | $1,093 | $14,821 | 2 | Universal Pictures International (UPI) | false | false |
| 10 | 9 | Inkheart | $1,170 | -73.1% | 6 | - | $195 | $30,481 | 3 | - | false | false |
| 11 | 11 | The Curious Case of Benjamin Button | $609 | -71% | 5 | - | $121 | $181,606 | 7 | Garsu Pasaulio Irasai | false | false |
| 12 | 14 | Valkyrie | $495 | -63.1% | 2 | -2 | $247 | $71,921 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | 13 | Role Models | $430 | -76% | 1 | -2 | $430 | $30,905 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 15 | The Pink Panther 2 | $199 | -52.6% | - | - | - | $72,104 | 5 | ACME | false | false |
| 15 | - | Changeling | $195 | - | 2 | - | $97 | $69,386 | 9 | Universal Pictures International (UPI) | false | false |
| 16 | 19 | Revolutionary Road | $140 | +16.7% | 1 | - | $140 | $49,983 | 8 | Universal Pictures International (UPI) | false | false |
| 17 | 18 | Bedtime Stories | $80 | -44.4% | 1 | -1 | $80 | $58,274 | 11 | Universal Pictures International (UPI) | false | false |
| 18 | - | The Tale of Despereaux | $76 | - | 1 | - | $76 | $251,014 | 13 | Universal Pictures International (UPI) | false | false |
| 19 | 20 | RocknRolla | $46 | +7% | - | - | - | $67,604 | 10 | Garsu Pasaulio Irasai | false | false |
