| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Confessions of a Shopaholic | $1,808,110 | - | 309 | - | $5,851 | $1,870,629 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Watchmen | $1,092,222 | -52.4% | 355 | - | $3,076 | $4,213,742 | 2 | Paramount Pictures International | false | false |
| 3 | 3 | Slumdog Millionaire | $467,962 | -23.7% | 212 | +5 | $2,207 | $11,712,982 | 13 | Icon Film Distribution | false | false |
| 4 | - | Notorious | $460,670 | - | 126 | - | $3,656 | $460,670 | 1 | 20th Century Fox International | true | false |
| 5 | - | Friday the 13th | $407,317 | - | 142 | - | $2,868 | $407,317 | 1 | Paramount Pictures International | true | false |
| 6 | 2 | He's Just Not That Into You | $388,522 | -42% | 226 | -24 | $1,719 | $8,947,250 | 5 | Roadshow Films | false | false |
| 7 | 4 | Gran Torino | $377,395 | -17.8% | 199 | -4 | $1,896 | $9,344,988 | 8 | Roadshow Films | false | false |
| 8 | - | Easy Virtue | $220,769 | - | 49 | - | $4,505 | $276,972 | 1 | Hopscotch Films | true | false |
| 9 | 8 | The Reader | $215,371 | -16.7% | 53 | - | $4,063 | $1,708,449 | 4 | Roadshow Films | false | false |
| 10 | 6 | Last Chance Harvey | $179,494 | -39.7% | 144 | - | $1,246 | $1,279,576 | 3 | Icon Film Distribution | false | false |
| 11 | - | Love the Beast | $159,136 | - | 59 | - | $2,697 | $186,914 | 1 | Madman Entertainment | true | false |
| 12 | 7 | The Unborn | $151,161 | -49% | 125 | +2 | $1,209 | $1,301,730 | 3 | Universal Pictures International (UPI) | false | false |
| 13 | 5 | New in Town | $150,420 | -53.5% | 169 | +2 | $890 | $637,136 | 2 | Icon Film Distribution | false | false |
| 14 | 9 | The International | $82,789 | -62% | 105 | -108 | $788 | $2,025,013 | 4 | Sony Pictures Releasing | false | false |
| 15 | 14 | Twilight | $67,827 | -17.5% | 62 | -6 | $1,093 | $13,895,410 | 15 | - | false | false |
| 16 | 13 | Changeling | $56,015 | -40.1% | 88 | -4 | $636 | $2,413,656 | 6 | Universal Pictures International (UPI) | false | false |
| 17 | 18 | Milk | $54,407 | +4.4% | 42 | - | $1,295 | $1,162,787 | 7 | Universal Pictures International (UPI) | false | false |
| 18 | 15 | Hotel for Dogs | $53,115 | -35.2% | 102 | -37 | $520 | $4,069,564 | 9 | Paramount Pictures International | false | false |
| 19 | 12 | The Combination | $48,241 | -50.5% | 29 | -5 | $1,663 | $362,177 | 3 | - | false | false |
| 20 | 10 | Ghost Town | $43,670 | -68.5% | 79 | -93 | $552 | $2,512,531 | 5 | Paramount Pictures International | false | false |
| 21 | 19 | Dean Spanley 2008 Re-release | $40,513 | -18.2% | 34 | - | $1,191 | $127,950 | 2 | Paramount Pictures International | false | false |
| 22 | 16 | The Secret Life of Bees | $40,280 | -47.5% | 44 | - | $915 | $187,700 | 2 | 20th Century Fox International | false | false |
| 23 | 17 | Australia | $30,677 | -49.3% | 40 | -34 | $766 | $24,359,707 | 16 | 20th Century Fox International | false | false |
| 24 | 11 | Zack and Miri Make a Porno | $26,836 | -78% | 42 | -78 | $638 | $1,257,907 | 4 | Roadshow Films | false | false |
| 25 | - | My Bloody Valentine | $20,310 | - | 16 | - | $1,269 | $1,164,899 | 5 | Hoyts Distribution | false | false |
| 26 | 28 | Revolutionary Road | $12,901 | -4.9% | 19 | -16 | $679 | $2,003,370 | 8 | Paramount Pictures International | false | false |
| 27 | - | Wild Ocean | $11,780 | - | 2 | - | $5,890 | $1,128,898 | 39 | IMAX | false | false |
| 28 | 21 | Underworld: Rise of the Lycans | $11,336 | -55% | 23 | -25 | $492 | $3,203,833 | 8 | Sony Pictures Releasing | false | false |
| 29 | - | I've Loved You So Long | $11,277 | - | 19 | - | $593 | $1,400,783 | 12 | Palace Films | false | false |
| 30 | - | The Curious Case of Benjamin Button | $8,481 | - | 21 | - | $403 | $10,849,488 | 12 | Warner Bros. | false | false |
| 31 | - | Of Time and the City | $8,359 | - | 4 | - | $2,089 | $8,359 | 1 | Sharmill Films | true | false |
| 32 | 22 | W. | $7,588 | -68.2% | 16 | -32 | $474 | $155,602 | 3 | Hoyts Distribution | false | false |
| 33 | 37 | Frost/Nixon | $6,863 | +379.9% | 8 | -5 | $857 | $1,335,208 | 12 | Universal Pictures International (UPI) | false | false |
| 34 | 20 | Bride Wars | $6,715 | -85.3% | 25 | -25 | $268 | $7,545,821 | 9 | 20th Century Fox International | false | false |
| 35 | 29 | Valkyrie | $6,166 | -52.7% | 16 | -22 | $385 | $4,103,918 | 8 | 20th Century Fox International | false | false |
| 36 | - | Transporter 3 | $6,119 | - | 22 | - | $278 | $2,147,477 | 6 | Icon Film Distribution | false | false |
| 37 | 26 | Rachel Getting Married | $5,556 | -67.4% | 10 | -18 | $555 | $424,418 | 5 | Sony Pictures Releasing | false | false |
| 38 | 32 | The Class | $5,222 | -20.7% | 6 | -1 | $870 | $256,619 | 8 | Sony Pictures Releasing | false | false |
| 39 | 27 | Beautiful | $4,918 | -65.7% | 20 | +1 | $245 | $27,993 | 2 | Jump Street Films | false | false |
| 40 | 34 | Frozen River | $4,878 | -2.7% | 3 | - | $1,626 | $34,301 | 4 | Sony Pictures Releasing | false | false |
| 41 | - | Deep Sea | $4,740 | - | 2 | - | $2,370 | $3,387,375 | 159 | IMAX | false | false |
| 42 | 25 | Marley & Me | $4,645 | -74.4% | 12 | -16 | $387 | $6,591,686 | 11 | 20th Century Fox International | false | false |
| 43 | 36 | Fly Me to the Moon 3D | $4,507 | +147.4% | 2 | - | $2,253 | $466,592 | 26 | IMAX | false | false |
| 44 | 31 | The Tale of Despereaux | $4,294 | -57.3% | 16 | -10 | $268 | $1,564,903 | 10 | Universal Pictures International (UPI) | false | false |
| 45 | - | Dinosaurs: Giants of Patagonia | $4,170 | - | 2 | - | $2,085 | $2,080,142 | 93 | IMAX | false | false |
| 46 | 30 | Role Models | $2,410 | -78.1% | 10 | -14 | $241 | $4,308,801 | 9 | Universal Pictures International (UPI) | false | false |
| 47 | - | Appaloosa | $2,385 | - | 10 | - | $238 | $2,800 | 1 | Roadshow Films | true | false |
| 48 | - | Grand Canyon Adventure: River at Risk | $2,323 | - | 1 | - | $2,323 | $362,680 | 39 | IMAX | false | false |
| 49 | - | The Human Body Undated Australia Release | $1,957 | - | 2 | - | $978 | $996,399 | 29 | IMAX | false | false |
| 50 | - | African Adventure: Safari in the Okavango | $1,683 | - | 1 | - | $1,683 | $744,917 | 104 | IMAX | false | false |
| 51 | - | Australia: Land Beyond Time Undated Australia Release | $764 | - | 1 | - | $764 | $560,128 | 29 | IMAX | false | false |
| 52 | 38 | Under the Sea 3D | $718 | -42.1% | 1 | - | $718 | $3,560 | 3 | IMAX | false | false |
| 53 | - | Bugs! | $497 | - | 1 | - | $497 | $1,709,995 | 310 | N/A | false | false |
| 54 | - | Antarctica | $390 | - | 1 | - | $390 | $3,948,599 | - | IMAX | - | false |
| 55 | - | Shackleton's Antarctic Adventure | $386 | - | 1 | - | $386 | $4,025,004 | 385 | N/A | false | false |
| 56 | - | Mysteries of Egypt | $328 | - | 2 | - | $164 | $4,105,336 | - | IMAX | - | false |
| 57 | - | Greece: Secrets of the Past Undated Australia Release | $264 | - | 1 | - | $264 | $220,941 | 29 | IMAX | false | false |
