| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Slumdog Millionaire | $47,324 | - | 5 | - | $9,464 | $47,324 | 1 | N/A | true | false |
| 2 | 1 | Charbel | $33,637 | -9.2% | 5 | - | $6,727 | $192,156 | 5 | Italian International Film | false | false |
| 3 | 2 | The International | $21,324 | -40.8% | 6 | - | $3,554 | $67,695 | 2 | N/A | false | false |
| 4 | - | Marley & Me | $20,127 | - | 3 | - | $6,709 | $20,127 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Confessions of a Shopaholic | $18,893 | -44.1% | 6 | - | $3,148 | $60,964 | 2 | Walt Disney Pictures | false | false |
| 6 | 4 | The Pink Panther 2 | $16,351 | -39.5% | 6 | +1 | $2,725 | $160,063 | 4 | N/A | false | false |
| 7 | 5 | The Curious Case of Benjamin Button | $15,445 | -40.2% | 6 | -1 | $2,574 | $113,756 | 3 | N/A | false | false |
| 8 | - | Watchmen | $15,107 | - | 8 | - | $1,888 | $15,107 | 1 | N/A | true | false |
| 9 | 6 | Killshot | $10,504 | -26.4% | 6 | - | $1,750 | $29,233 | 2 | N/A | false | false |
| 10 | 7 | Bride Wars | $7,733 | -28.9% | 4 | -1 | $1,933 | $140,963 | 5 | N/A | false | false |
| 11 | 9 | Whatever Lola Wants | $7,668 | -8.3% | 3 | - | $2,556 | $32,867 | 3 | N/A | false | false |
| 12 | 8 | My Best Friend's Girl | $7,157 | -29.6% | 3 | -1 | $2,385 | $54,499 | 4 | N/A | false | false |
| 13 | 12 | Al Dadda Doody | $5,203 | -0.6% | 4 | - | $1,300 | $169,767 | 12 | N/A | false | false |
| 14 | 10 | Yes Man | $4,296 | -34.5% | 3 | -1 | $1,432 | $253,989 | 9 | N/A | false | false |
| 15 | 13 | Valkyrie | $2,014 | -53% | 3 | -3 | $671 | $259,740 | 8 | N/A | false | false |
| 16 | 16 | Beirut Open City | $1,987 | -21.9% | 2 | - | $993 | $168,845 | 13 | N/A | false | false |
| 17 | 14 | The Tale of Despereaux | $1,630 | -58.4% | 3 | -2 | $543 | $46,579 | 6 | N/A | false | false |
| 18 | 17 | Saw V | $1,501 | -31.3% | 1 | -1 | $1,501 | $4,310 | 2 | N/A | false | false |
| 19 | 20 | Outlander | $1,329 | +4.1% | 2 | - | $664 | $22,942 | 4 | N/A | false | false |
| 20 | 19 | Revolutionary Road | $995 | -45% | 2 | -1 | $497 | $87,623 | 7 | N/A | false | false |
| 21 | 23 | Bedtime Stories | $804 | +29.3% | 2 | - | $402 | $148,488 | 11 | N/A | false | false |
| 22 | 26 | Underworld: Rise of the Lycans | $434 | +5.1% | 1 | - | $434 | $69,443 | 7 | N/A | false | false |
| 23 | 25 | Genghis Khan: To the Ends of the Earth and Sea | $360 | -25% | 2 | - | $180 | $21,250 | 6 | N/A | false | false |
| 24 | 24 | A French Gigolo | $303 | -39.4% | 1 | - | $303 | $4,583 | 5 | N/A | false | false |
| 25 | 11 | Frost/Nixon | $87 | -98.4% | 1 | -4 | $87 | $7,010 | 2 | N/A | false | false |
