| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Pink Panther 2 | $152,739 | - | 75 | - | $2,036 | $152,739 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | - | The Curious Case of Benjamin Button | $139,645 | - | 55 | - | $2,539 | $139,645 | 1 | NuMetro Distribution | true | false |
| 3 | 1 | He's Just Not That Into You | $76,970 | -17.3% | 51 | +1 | $1,509 | $445,579 | 3 | NuMetro Distribution | false | false |
| 4 | 2 | Bedtime Stories | $51,553 | -9.6% | 53 | -2 | $972 | $448,098 | 5 | Ster-Kinekor Pictures | false | false |
| 5 | 4 | Bride Wars | $39,688 | -15.4% | 61 | - | $650 | $675,585 | 6 | NuMetro Distribution | false | false |
| 6 | 3 | Inkheart | $36,727 | -24% | 41 | +1 | $895 | $99,670 | 2 | NuMetro Distribution | false | false |
| 7 | 5 | Seven Pounds | $34,188 | -26% | 46 | -4 | $743 | $211,511 | 3 | Ster-Kinekor Pictures | false | false |
| 8 | 6 | Changeling | $32,181 | -23.2% | 29 | - | $1,109 | $96,214 | 2 | United International Pictures | false | false |
| 9 | 7 | Notorious | $26,723 | -7.8% | 25 | - | $1,068 | $70,524 | 2 | NuMetro Distribution | false | false |
| 10 | 9 | Role Models | $19,011 | -22.9% | 35 | -4 | $543 | $186,596 | 4 | United International Pictures | false | false |
| 11 | 8 | Transporter 3 | $17,054 | -36.3% | 36 | -20 | $473 | $696,879 | 7 | United International Pictures | false | false |
| 12 | - | The Longshots | $14,661 | - | 17 | - | $862 | $14,661 | 1 | Ster-Kinekor Pictures | true | false |
| 13 | 11 | The Secret Life of Bees | $12,954 | -20.6% | 23 | -1 | $563 | $125,388 | 4 | NuMetro Distribution | false | false |
| 14 | 10 | Valkyrie | $11,458 | -48.4% | 29 | -19 | $395 | $321,143 | 5 | NuMetro Distribution | false | false |
| 15 | 12 | The Wrestler | $9,895 | -38.1% | 13 | - | $761 | $33,664 | 2 | United International Pictures | false | false |
| 16 | 16 | Doubt | $9,115 | -14.5% | 10 | +1 | $911 | $74,238 | 4 | Ster-Kinekor Pictures | false | false |
| 17 | 18 | Mr. Bones 2: Back from the Past | $8,529 | -2.5% | 17 | -6 | $501 | $3,629,391 | 14 | United International Pictures | false | false |
| 18 | 17 | The Duchess | $8,182 | -18.8% | 11 | -1 | $743 | $114,990 | 5 | Ster-Kinekor Pictures | false | false |
| 19 | 14 | Billu | $8,123 | -41.5% | 5 | - | $1,624 | $51,218 | 3 | NuMetro Distribution | false | false |
| 20 | 20 | Bolt | $7,299 | -5.9% | 14 | -3 | $521 | $930,116 | 10 | Ster-Kinekor Pictures | false | false |
| 21 | 19 | Revolutionary Road | $5,225 | -35.3% | 13 | -5 | $401 | $175,422 | 6 | United International Pictures | false | false |
| 22 | - | Vicky Cristina Barcelona | $3,556 | - | 7 | - | $508 | $179,438 | 9 | United International Pictures | false | false |
| 23 | 22 | Burn After Reading | $2,901 | -53.4% | 7 | -4 | $414 | $273,511 | 8 | Ster-Kinekor Pictures | false | false |
| 24 | 25 | Frost/Nixon | $2,211 | -35.7% | 3 | - | $737 | $40,554 | 5 | United International Pictures | false | false |
| 25 | 21 | Four Christmases | $2,012 | -68.1% | 5 | -14 | $402 | $504,597 | 8 | NuMetro Distribution | false | false |
| 26 | 28 | Killshot | $739 | -63% | 3 | -4 | $246 | $53,687 | 6 | Ster-Kinekor Pictures | false | false |
| 27 | 23 | Appaloosa | $736 | -84% | 3 | -7 | $245 | $20,363 | 3 | NuMetro Distribution | false | false |
| 28 | 29 | Igor | $460 | -76.9% | 3 | -6 | $153 | $34,710 | 6 | Ster-Kinekor Pictures | false | false |
| 29 | - | Ghost Town | $188 | - | 2 | - | $94 | $15,654 | 5 | United International Pictures | false | false |
| 30 | 30 | Pride and Glory | $80 | -95.7% | 1 | -2 | $80 | $221,782 | 9 | NuMetro Distribution | false | false |
