| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Pink Panther 2 | $352,874 | - | 19 | - | $18,572 | $352,874 | 1 | N/A | true | false |
| 2 | 1 | The Unborn | $102,064 | -62.6% | 19 | -1 | $5,371 | $440,077 | 2 | N/A | false | false |
| 3 | - | Solstice | $100,547 | - | 19 | - | $5,291 | $100,547 | 1 | N/A | true | false |
| 4 | - | Role Models | $78,105 | - | 11 | - | $7,100 | $78,105 | 1 | N/A | true | false |
| 5 | 3 | Slumdog Millionaire | $73,059 | -38.1% | 13 | -2 | $5,619 | $844,552 | 4 | Gulf Film | false | false |
| 6 | - | Appaloosa | $61,953 | - | 15 | - | $4,130 | $61,953 | 1 | N/A | true | false |
| 7 | 2 | Inkheart | $52,028 | -65.1% | 11 | -8 | $4,729 | $236,069 | 2 | N/A | false | false |
| 8 | 5 | The Tale of Despereaux | $39,069 | -37.5% | 15 | -5 | $2,604 | $256,358 | 3 | N/A | false | false |
| 9 | - | The Wrestler | $31,725 | - | 11 | - | $2,884 | $31,725 | 1 | N/A | true | false |
| 10 | 6 | Yes Man | $24,737 | -55.4% | 4 | -4 | $6,184 | $678,308 | 4 | N/A | false | false |
| 11 | 4 | Killshot | $20,047 | -78.1% | 10 | -2 | $2,004 | $143,245 | 2 | N/A | false | false |
| 12 | 9 | Seven Pounds | $15,735 | -67.3% | 4 | -4 | $3,933 | $275,653 | 3 | N/A | false | false |
| 13 | - | Hosh Ala Wakah Mink | $13,750 | - | 8 | - | $1,718 | $17,999 | 1 | N/A | true | false |
| 14 | 12 | Sorry to Disturb | $8,989 | -50.3% | 6 | -2 | $1,498 | $400,981 | 4 | N/A | false | false |
| 15 | 7 | How to Lose Friends & Alienate People | $8,161 | -84.1% | 5 | -8 | $1,632 | $74,859 | 2 | N/A | false | false |
| 16 | 13 | Valkyrie | $6,687 | -37.6% | 1 | -1 | $6,687 | $582,766 | 5 | N/A | false | false |
| 17 | 11 | My Mom's New Boyfriend | $5,246 | -84.1% | 2 | -11 | $2,623 | $149,722 | 3 | N/A | false | false |
| 18 | 17 | Revolutionary Road | $4,801 | -11.5% | 1 | - | $4,801 | $118,079 | 4 | N/A | false | false |
| 19 | 19 | Madagascar: Escape 2 Africa | $3,369 | +9.3% | 1 | -1 | $3,369 | $1,886,243 | 12 | N/A | false | false |
| 20 | 8 | Shikamara | $2,757 | -94.3% | 3 | -11 | $919 | $66,351 | 2 | N/A | false | false |
| 21 | 21 | Twilight | $1,534 | -27.3% | 1 | - | $1,534 | $1,243,286 | 11 | N/A | false | false |
| 22 | 10 | The Spirit | $1,261 | -96.9% | 1 | -17 | $1,261 | $269,520 | 3 | N/A | false | false |
| 23 | 20 | Changeling | $781 | -74.1% | 1 | - | $781 | $278,077 | 6 | N/A | false | false |
| 24 | 14 | The Fall | $764 | -92.4% | 1 | -6 | $764 | $14,037 | 2 | N/A | false | false |
| 25 | 23 | City of Ember | $221 | -78.8% | 1 | - | $221 | $209,560 | 6 | N/A | false | false |
