| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | If I Were You 2 | $1,013,065 | -25.4% | 311 | +20 | $3,257 | $15,531,550 | 5 | 20th Century Fox International | false | false |
| 2 | - | Yes Man | $855,424 | - | 151 | - | $5,665 | $855,424 | 1 | Warner Bros. | true | false |
| 3 | 2 | The Curious Case of Benjamin Button | $832,332 | -18.6% | 199 | - | $4,182 | $4,195,182 | 3 | Warner Bros. | false | false |
| 4 | 3 | Bedtime Stories | $512,183 | -29.3% | 206 | +1 | $2,486 | $1,883,288 | 2 | Walt Disney Pictures | false | false |
| 5 | - | Revolutionary Road | $271,594 | - | 80 | - | $3,394 | $271,594 | 1 | Paramount Pictures International | true | false |
| 6 | 5 | Australia | $206,233 | -50.7% | 174 | +1 | $1,185 | $870,699 | 2 | 20th Century Fox International | false | false |
| 7 | 7 | Marley & Me | $169,295 | -40.6% | 161 | -6 | $1,051 | $5,815,037 | 6 | 20th Century Fox International | false | false |
| 8 | 4 | The Day the Earth Stood Still | $164,136 | -61.6% | 262 | -46 | $626 | $4,970,347 | 4 | 20th Century Fox International | false | false |
| 9 | 8 | Bolt | $134,933 | -32.9% | 195 | -4 | $691 | $3,872,917 | 5 | Walt Disney Pictures | false | false |
| 10 | 6 | Four Christmases | $133,844 | -59.6% | 153 | - | $874 | $801,550 | 2 | PlayArte Pictures | false | false |
| 11 | 9 | Madagascar: Escape 2 Africa | $95,670 | -46.6% | 211 | -101 | $453 | $16,329,950 | 8 | Paramount Pictures International | false | false |
| 12 | 10 | Seven Pounds | $59,003 | -46% | 137 | +2 | $430 | $4,546,397 | 6 | Sony Pictures Releasing | false | false |
| 13 | 12 | Twilight | $56,858 | -38.5% | 134 | -40 | $424 | $6,258,386 | 7 | Paris Filmes | false | false |
| 14 | 13 | Changeling | $44,974 | -36.9% | 49 | -9 | $917 | $884,622 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 11 | The Tale of Despereaux | $40,161 | -59.8% | 116 | -14 | $346 | $713,014 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | 15 | Deep Sea | $39,439 | -19.2% | 1 | - | $39,439 | $216,482 | 3 | IMAX | false | false |
| 17 | - | The Nest | $30,436 | - | 17 | - | $1,790 | $37,349 | 1 | Imovision | true | false |
| 18 | 17 | Vicky Cristina Barcelona | $20,815 | -7.1% | 29 | -2 | $717 | $2,458,108 | 12 | Imagem Filmes | false | false |
| 19 | 16 | The Happy Cricket and the Giant Bugs | $17,957 | -36.2% | 105 | -8 | $171 | $505,503 | 4 | 20th Century Fox International | false | false |
| 20 | 14 | Quarantine | $11,841 | -76.1% | 34 | -36 | $348 | $375,237 | 3 | Sony Pictures Releasing | false | false |
| 21 | 24 | Burn After Reading | $11,784 | +100.4% | 23 | +7 | $512 | $2,054,384 | 10 | Universal Pictures International (UPI) | false | false |
| 22 | 18 | Rumba | $9,362 | -41.2% | 2 | -1 | $4,681 | $32,850 | 2 | Filmes do Estação | false | false |
| 23 | 35 | Transporter 3 | $8,170 | +612.3% | 22 | +11 | $371 | $654,185 | 8 | Imagem Filmes | false | false |
| 24 | 19 | Arranged 2009 Re-release | $6,730 | -48% | 7 | -3 | $961 | $70,641 | 4 | Moviemobz Rain | false | false |
| 25 | 23 | Be Kind Rewind | $6,462 | +2.4% | 9 | +2 | $718 | $175,478 | 8 | Europa Filmes | false | false |
| 26 | 21 | Café de los maestros | $5,910 | -35.1% | 9 | +1 | $656 | $108,161 | 6 | VideoFilmes | false | false |
| 27 | 20 | Titãs: A Vida Até Parece uma Festa | $5,798 | -36.7% | 11 | -4 | $527 | $45,125 | 3 | Moviemobz Rain | false | false |
| 28 | 22 | Inkheart | $5,756 | -18% | 35 | +28 | $164 | $1,217,594 | 6 | PlayArte Pictures | false | false |
| 29 | 26 | The Boy in the Striped Pajamas | $4,797 | +5.9% | 8 | -1 | $599 | $247,440 | 8 | Walt Disney Pictures | false | false |
| 30 | 28 | Good | $2,847 | -22.1% | 14 | +6 | $203 | $192,725 | 6 | Imagem Filmes | false | false |
| 31 | 42 | The Duchess | $2,375 | +394.8% | 7 | +5 | $339 | $451,051 | 11 | Paramount Pictures International | false | false |
| 32 | 25 | Juventude | $2,297 | -57.8% | 5 | - | $459 | $65,027 | 6 | Filmes do Estação | false | false |
| 33 | 27 | Appaloosa | $1,987 | -52.8% | 2 | -1 | $993 | $52,082 | 9 | PlayArte Pictures | false | false |
| 34 | 30 | Not on the Lips 2009 Re-release | $1,290 | -52.3% | 1 | - | $1,290 | $11,367 | 3 | Pandora Filmproduktion | false | false |
| 35 | 40 | High School Musical 3: Senior Year | $1,257 | +138.1% | 15 | +7 | $83 | $5,575,000 | 15 | Walt Disney Pictures | false | false |
| 36 | 31 | A New American Century | $1,035 | -51.2% | 3 | - | $345 | $4,258 | 2 | Moviemobz Rain | false | false |
| 37 | 34 | Taxi to the Dark Side | $856 | -35% | 4 | +1 | $214 | $3,011 | 2 | Moviemobz Rain | false | false |
| 38 | 33 | Body of Lies | $791 | -49% | 3 | -2 | $263 | $1,605,488 | 10 | Warner Bros. | false | false |
| 39 | 38 | Quantum of Solace | $715 | +33.4% | 2 | -4 | $357 | $7,375,761 | 13 | Sony Pictures Releasing | false | false |
| 40 | 41 | Romance | $612 | +23.9% | 12 | +7 | $51 | $872,751 | 12 | Walt Disney Pictures | false | false |
| 41 | - | Lemon Tree | $599 | - | 2 | - | $299 | $261,691 | 26 | Imovision | false | false |
| 42 | 32 | The Witnesses | $492 | -76.3% | 1 | - | $492 | $11,489 | 3 | Filmes do Estação | false | false |
| 43 | 44 | Blame it on Fidel | $282 | -34% | 1 | - | $282 | $689,102 | 59 | Filmes do Estação | false | false |
| 44 | 50 | In Bruges | $276 | +89% | 1 | -1 | $276 | $208,292 | 16 | Paris Filmes | false | false |
| 45 | 43 | The Singer (Quand j'étais chanteur) | $266 | -43.9% | 3 | +1 | $88 | $110,907 | 36 | California Filmes | false | false |
| 46 | 57 | Happy Desert | $217 | +1,176.5% | 3 | +1 | $72 | $21,844 | 10 | Filmes do Estação | false | false |
| 47 | - | Fly Me to the Moon 3D | $110 | - | 3 | - | $36 | $1,683,313 | 17 | PlayArte Pictures | false | false |
| 48 | 37 | REC | $60 | -89% | 1 | -2 | $60 | $605,899 | 12 | California Filmes | false | false |
| 49 | 46 | Step Brothers | $49 | -84.1% | 1 | -1 | $49 | $219,207 | 15 | Sony Pictures Releasing | false | false |
