| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Paul Blart: Mall Cop | $39,234,238 | - | 3,144 | - | $12,479 | $39,234,238 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Gran Torino | $25,606,399 | - | 2,972 | - | $8,615 | $76,603,810 | 6 | Warner Bros. | false | false |
| 3 | - | My Bloody Valentine | $24,103,962 | - | 2,534 | - | $9,512 | $24,103,962 | 1 | Lionsgate | true | false |
| 4 | - | Notorious | $23,393,472 | - | 1,638 | - | $14,281 | $23,393,472 | 1 | - | true | false |
| 5 | - | Hotel for Dogs | $22,865,512 | - | 3,271 | - | $6,990 | $22,865,512 | 1 | DreamWorks | true | false |
| 6 | - | Bride Wars | $13,878,727 | - | 3,228 | - | $4,299 | $39,705,852 | 2 | Twentieth Century Fox | false | false |
| 7 | - | The Unborn | $10,545,075 | - | 2,359 | - | $4,470 | $33,784,230 | 2 | Universal Pictures | false | false |
| 8 | - | Defiance | $10,510,082 | - | 1,789 | - | $5,874 | $10,850,710 | 3 | Paramount Vantage | false | false |
| 9 | - | Marley & Me | $7,514,652 | - | 2,952 | - | $2,545 | $133,923,935 | 4 | Twentieth Century Fox | false | false |
| 10 | - | Slumdog Millionaire | $7,021,727 | - | 582 | - | $12,064 | $43,858,932 | 10 | - | false | false |
| 11 | - | The Curious Case of Benjamin Button | $6,585,296 | - | 2,223 | - | $2,962 | $103,610,033 | 4 | Paramount Pictures | false | false |
| 12 | - | Bedtime Stories | $6,168,048 | - | 2,619 | - | $2,355 | $105,073,339 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 13 | - | Last Chance Harvey | $5,011,596 | - | 1,054 | - | $4,754 | $5,602,513 | 4 | Overture Films | false | false |
| 14 | - | Valkyrie | $4,556,379 | - | 2,007 | - | $2,270 | $78,276,485 | 4 | United Artists | false | false |
| 15 | - | Yes Man | $3,088,360 | - | 1,704 | - | $1,812 | $94,043,254 | 5 | Warner Bros. | false | false |
| 16 | - | Not Easily Broken | $2,370,071 | - | 725 | - | $3,269 | $8,514,052 | 2 | Screen Gems | false | false |
| 17 | - | Revolutionary Road | $2,158,979 | - | 171 | - | $12,625 | $6,109,157 | 4 | Paramount Vantage | false | false |
| 18 | - | Twilight | $2,119,782 | - | 904 | - | $2,344 | $184,585,393 | 9 | Summit Entertainment | false | false |
| 19 | - | The Wrestler | $2,044,246 | - | 144 | - | $14,196 | $5,356,214 | 5 | - | false | false |
| 20 | - | The Reader | $1,518,171 | - | 417 | - | $3,640 | $7,808,169 | 6 | The Weinstein Company | false | false |
| 21 | - | Doubt | $1,474,755 | - | 725 | - | $2,034 | $25,506,742 | 6 | Miramax | false | false |
| 22 | - | Seven Pounds | $1,412,836 | - | 1,121 | - | $1,260 | $69,369,933 | 5 | Sony Pictures Releasing | false | false |
| 23 | - | The Tale of Despereaux | $1,026,795 | - | 870 | - | $1,180 | $49,185,300 | 5 | Universal Pictures | false | false |
| 24 | - | Milk | $942,359 | - | 223 | - | $4,225 | $20,543,583 | 8 | Focus Features | false | false |
| 25 | - | Frost/Nixon | $818,615 | - | 153 | - | $5,350 | $8,777,776 | 7 | Universal Pictures | false | false |
| 26 | - | Madagascar: Escape 2 Africa | $687,452 | - | 334 | - | $2,058 | $178,254,537 | 11 | DreamWorks | false | false |
| 27 | - | CC2C | $685,798 | - | 130 | - | $5,275 | $685,798 | 1 | Warner Bros. | true | false |
| 28 | - | The Day the Earth Stood Still | $537,934 | - | 311 | - | $1,729 | $78,370,300 | 6 | Twentieth Century Fox | false | false |
| 29 | - | Bolt | $489,735 | - | 339 | - | $1,444 | $112,581,719 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 30 | - | Quantum of Solace | $395,678 | - | 329 | - | $1,202 | $168,054,668 | 10 | Sony Pictures Releasing | false | false |
| 31 | - | Australia | $345,509 | - | 287 | - | $1,203 | $48,383,437 | 8 | Twentieth Century Fox | false | false |
| 32 | - | Four Christmases | $326,300 | - | 362 | - | $901 | $119,651,861 | 8 | Warner Bros. | false | false |
| 33 | - | Che: Part One/Che: Part Two | $198,510 | - | 25 | - | $7,940 | $523,229 | 6 | IFC Films | false | false |
| 34 | - | Beverly Hills Chihuahua | $174,438 | - | 193 | - | $903 | $94,286,898 | 16 | Walt Disney Studios Motion Pictures | false | false |
| 35 | - | Rachel Getting Married | $126,401 | - | 62 | - | $2,038 | $10,758,023 | 16 | Sony Pictures Classics | false | false |
| 36 | - | Role Models | $122,495 | - | 187 | - | $655 | $67,160,685 | 11 | Universal Pictures | false | false |
| 37 | - | Vicky Cristina Barcelona | $102,289 | - | 88 | - | $1,162 | $23,016,104 | 23 | - | false | false |
| 38 | - | Waltz with Bashir | $97,628 | - | 9 | - | $10,847 | $551,146 | 4 | Sony Pictures Classics | false | false |
| 39 | - | The Spirit | $91,350 | - | 168 | - | $543 | $19,781,879 | 4 | Lionsgate | false | false |
| 40 | - | Sea Monsters: A Prehistoric Adventure | $88,371 | - | 21 | - | $4,208 | $20,654,766 | 68 | National Geographic Entertainment | false | false |
| 41 | - | Happy-Go-Lucky | $71,824 | - | 51 | - | $1,408 | $3,494,485 | 15 | Miramax | false | false |
| 42 | - | High School Musical 3: Senior Year | $70,238 | - | 155 | - | $453 | $90,499,322 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 43 | - | Let the Right One In | $67,778 | - | 39 | - | $1,737 | $1,686,959 | 13 | Magnolia Pictures | false | false |
| 44 | - | I've Loved You So Long | $50,529 | - | 23 | - | $2,196 | $2,543,350 | 13 | Sony Pictures Classics | false | false |
| 45 | - | Synecdoche, New York | $45,544 | - | 33 | - | $1,380 | $2,859,110 | 13 | Sony Pictures Classics | false | false |
| 46 | - | The Secret Life of Bees | $43,403 | - | 58 | - | $748 | $37,665,012 | 14 | - | false | false |
| 47 | - | The Boy in the Striped Pajamas | $42,499 | - | 58 | - | $732 | $9,030,581 | 11 | Miramax | false | false |
| 48 | - | Space Station 3D | $37,913 | - | 9 | - | $4,212 | $77,450,262 | 353 | IMAX | false | false |
| 49 | - | Magnificent Desolation: Walking on the Moon | $37,635 | - | 6 | - | $6,272 | $27,244,473 | 174 | IMAX | false | false |
| 50 | - | Ghajini | $33,597 | - | 22 | - | $1,527 | $2,444,668 | 4 | Adlabs Films | false | false |
| 51 | - | Soul Men | $31,365 | - | 90 | - | $348 | $12,057,992 | 11 | - | false | false |
| 52 | - | Roving Mars | $23,686 | - | 7 | - | $3,383 | $9,907,975 | 156 | Walt Disney Studios Motion Pictures | false | false |
| 53 | - | Zack and Miri Make a Porno | $23,193 | - | 50 | - | $463 | $31,434,309 | 12 | The Weinstein Company | false | false |
| 54 | - | Made in U.S.A | $20,467 | - | 2 | - | $10,233 | $39,885 | 2 | Rialto Pictures | false | false |
| 55 | - | Silent Light | $15,605 | - | 1 | - | $15,605 | $38,964 | 2 | Palisades Tartan | false | false |
| 56 | - | Appaloosa | $14,475 | - | 49 | - | $295 | $20,207,003 | 18 | Warner Bros. | false | false |
| 57 | - | A Christmas Tale | $14,225 | - | 20 | - | $711 | $1,046,175 | 10 | IFC Films | false | false |
| 58 | - | The Haunting of Molly Hartley | $13,199 | - | 12 | - | $1,099 | $13,538,782 | 12 | Freestyle Releasing | false | false |
| 59 | - | Deep Sea | $12,921 | - | 6 | - | $2,153 | $37,363,109 | 151 | Warner Bros. | false | false |
| 60 | - | Wendy and Lucy | $12,466 | - | 4 | - | $3,116 | $159,653 | 6 | Oscilloscope | false | false |
| 61 | - | Owl and the Sparrow | $11,016 | - | 3 | - | $3,672 | $11,016 | 1 | Wave Releasing | true | false |
| 62 | - | The Dark Knight | $9,856 | - | 6 | - | $1,642 | $531,037,655 | 27 | Warner Bros. | false | false |
| 63 | - | Lola Montès | $9,146 | - | 1 | - | $9,146 | $101,710 | 15 | Rialto Pictures | false | false |
| 64 | - | Nothing Like the Holidays | $9,084 | - | 23 | - | $394 | $7,496,496 | 6 | Overture Films | false | false |
| 65 | - | Timecrimes | $8,586 | - | 2 | - | $4,293 | $31,975 | 6 | Magnolia Pictures | false | false |
| 66 | - | Tell No One | $4,353 | - | 3 | - | $1,451 | $6,166,905 | 29 | Music Box Films | false | false |
| 67 | - | Cherry Blossoms | $4,178 | - | 1 | - | $4,178 | $4,178 | 1 | Strand Releasing | true | false |
| 68 | - | The Secret of the Grain | $4,040 | - | 1 | - | $4,040 | $55,361 | 4 | IFC Films | false | false |
| 69 | - | Just Another Love Story | $3,263 | - | 1 | - | $3,263 | $8,788 | - | Koch Lorber Films | - | false |
| 70 | - | U2 3D | $3,146 | - | 1 | - | $3,146 | $9,684,588 | 52 | National Geographic Entertainment | false | false |
| 71 | - | Igor | $2,767 | - | 8 | - | $345 | $19,528,188 | 18 | Metro-Goldwyn-Mayer (MGM) | false | false |
| 72 | - | The Betrayal | $2,130 | - | 1 | - | $2,130 | $15,094 | 9 | The Cinema Guild | false | false |
| 73 | - | The Secrets | $2,075 | - | 3 | - | $691 | $62,472 | 8 | Monterey Media | false | false |
| 74 | - | A Secret | $1,708 | - | 4 | - | $427 | $584,859 | 20 | Strand Releasing | false | false |
| 75 | - | Otto; or, Up with Dead People | $1,692 | - | 2 | - | $846 | $9,847 | 11 | Strand Releasing | false | false |
| 76 | - | Stranded | $1,600 | - | 3 | - | $533 | $70,821 | 13 | Zeitgeist Films | false | false |
| 77 | - | How About You | $1,496 | - | 1 | - | $1,496 | $54,461 | 10 | Strand Releasing | false | false |
| 78 | - | Harvard Beats Yale 29-29 | $1,460 | - | 2 | - | $730 | $69,202 | 9 | Kino International | false | false |
| 79 | - | Monsieur Verdoux | $1,091 | - | 1 | - | $1,091 | $42,422 | 45 | The Film Desk | false | false |
| 80 | - | Yonkers Joe | $790 | - | 2 | - | $395 | $3,994 | 2 | Magnolia Pictures | false | false |
| 81 | - | The Beautiful Truth | $689 | - | 1 | - | $689 | $14,283 | 10 | Cinema Libre Studio | false | false |
| 82 | - | Trouble the Water | $648 | - | 1 | - | $648 | $491,674 | 22 | Zeitgeist Films | false | false |
| 83 | - | Were the World Mine | $380 | - | 1 | - | $380 | $89,823 | 12 | - | false | false |
| 84 | - | The Wild Child | $375 | - | 1 | - | $375 | $32,901 | 11 | The Film Desk | false | false |
| 85 | - | The Village Barbershop | $120 | - | 1 | - | $120 | $120 | 1 | Monterey Media | true | false |
