| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Day the Earth Stood Still | $361,007 | -46.7% | 122 | +30 | $2,959 | $1,313,811 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Twilight | $283,968 | -41.2% | 77 | -2 | $3,687 | $984,114 | 2 | Alfa Films | false | false |
| 3 | - | Australia | $223,495 | - | 60 | - | $3,724 | $223,495 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | Madagascar: Escape 2 Africa | $208,110 | -28.9% | 143 | +27 | $1,455 | $4,913,216 | 6 | Paramount Pictures International | false | false |
| 5 | 4 | El ratón Pérez 2 | $130,418 | -41.4% | 89 | -3 | $1,465 | $465,498 | 2 | Walt Disney Pictures | false | false |
| 6 | - | Rudo y Cursi | $115,970 | - | 45 | - | $2,577 | $115,970 | 1 | United International Pictures | true | false |
| 7 | - | Asterix at the Olympic Games | $29,007 | - | 34 | - | $853 | $29,007 | 1 | Distribution Company | true | false |
| 8 | 5 | Four Christmases | $28,383 | -49.7% | 34 | -3 | $834 | $366,919 | 4 | Distribution Company | false | false |
| 9 | 6 | Body of Lies | $23,552 | -57.4% | 40 | -9 | $588 | $875,442 | 7 | Warner Bros. | false | false |
| 10 | 8 | The Duchess | $13,103 | -39.6% | 14 | -1 | $935 | $212,450 | 5 | United International Pictures | false | false |
| 11 | 10 | Quarantine | $8,286 | -51.4% | 24 | -3 | $345 | $318,338 | 6 | Sony Pictures Releasing | false | false |
| 12 | 11 | Righteous Kill | $7,939 | -45.8% | 17 | -2 | $467 | $551,785 | 8 | CDI Films | false | false |
| 13 | 13 | Che: Part One | $7,583 | -28.9% | 9 | -1 | $842 | $649,119 | 9 | Alfa Films | false | false |
| 14 | 7 | High School Musical 3: Senior Year | $7,390 | -69.9% | 17 | -31 | $434 | $1,174,546 | 7 | Walt Disney Pictures | false | false |
| 15 | - | Journey to the Center of the Earth | $7,349 | - | 3 | - | $2,449 | $918,285 | 26 | Distribution Company | false | false |
| 16 | - | The Tracker 2008 Re-release | $6,726 | - | 5 | - | $1,345 | $40,737 | 3 | IFA | false | false |
| 17 | 14 | The Pope's Toilet | $5,192 | -51.2% | 6 | -1 | $865 | $18,827 | 2 | Primer Plano Film Group | false | false |
| 18 | 21 | Fly Me to the Moon 3D | $4,591 | +56.2% | 8 | -27 | $573 | $124,330 | 4 | Distribution Company | false | false |
| 19 | 12 | Quantum of Solace | $4,175 | -65.4% | 6 | -2 | $695 | $1,146,870 | 10 | Sony Pictures Releasing | false | false |
| 20 | - | Late Bloomers | $3,258 | - | 3 | - | $1,086 | $62,374 | 7 | Primer Plano Film Group | false | false |
| 21 | 15 | Death Sentence | $2,525 | -73.4% | 6 | -15 | $420 | $182,577 | 6 | Distribution Company | false | false |
| 22 | 20 | Bella | $2,439 | -27.8% | 6 | +3 | $406 | $29,087 | 3 | CDI Films | false | false |
| 23 | 18 | Tear This Heart Out | $2,048 | -46.5% | 7 | +1 | $292 | $51,374 | 7 | 20th Century Fox International | false | false |
| 24 | 17 | My Mom's New Boyfriend | $1,620 | -61.7% | 6 | +2 | $270 | $145,889 | 9 | - | false | false |
| 25 | 16 | The Bank Job | $1,366 | -70.1% | 4 | -8 | $341 | $615,574 | 13 | Alfa Films | false | false |
| 26 | 28 | Planet Terror | $1,239 | +14.1% | 8 | - | $154 | $81,928 | 5 | Pachamama Cine | false | false |
| 27 | 22 | Elegy | $1,168 | -55.9% | 4 | -3 | $292 | $170,971 | 8 | Distribution Company | false | false |
| 28 | 9 | Ben X | $1,023 | -94.3% | 5 | -15 | $204 | $25,286 | 2 | Distribution Company | false | false |
| 29 | 26 | Red Like the Sky 2008 Re-release | $1,005 | -39.3% | 3 | - | $335 | $24,514 | 6 | Primer Plano Film Group | false | false |
| 30 | 23 | Flawless | $954 | -55.3% | 2 | -6 | $477 | $250,773 | 10 | Distribution Company | false | false |
| 31 | 35 | Max Payne | $894 | +98.7% | 5 | +3 | $178 | $166,171 | 8 | 20th Century Fox International | false | false |
| 32 | - | Aniceto | $884 | - | 3 | - | $294 | $130,248 | 31 | Primer Plano Film Group | false | false |
| 33 | 25 | Beverly Hills Chihuahua | $775 | -56.2% | 4 | -2 | $193 | $1,557,888 | 14 | Walt Disney Pictures | false | false |
| 34 | 34 | Manual of Love 2008 Re-release | $646 | +13.1% | 2 | - | $323 | $133,173 | 16 | Notro Films | false | false |
| 35 | 19 | RocknRolla | $614 | -83.5% | 3 | -7 | $204 | $75,686 | 5 | Warner Bros. | false | false |
| 36 | 30 | Fados | $579 | -20.4% | 1 | - | $579 | $33,340 | 7 | Distribution Company | false | false |
| 37 | 32 | The Boy in the Striped Pajamas | $519 | -14.1% | 3 | +1 | $173 | $75,519 | 6 | Walt Disney Pictures | false | false |
| 38 | 33 | Deception | $379 | -36.2% | 1 | - | $379 | $60,563 | 5 | Alfa Films | false | false |
| 39 | 36 | Burn After Reading | $320 | -27.3% | 1 | - | $320 | $844,170 | 12 | United International Pictures | false | false |
| 40 | 31 | Black Christmas | $278 | -61% | 1 | -4 | $278 | $95,544 | 9 | Distribution Company | false | false |
| 41 | 37 | Four Minutes | $258 | -36.3% | 1 | - | $258 | $157,121 | 20 | Alfa Films | false | false |
| 42 | 38 | My Brother is an Only Child | $240 | -13.7% | 1 | - | $240 | $219,610 | 17 | Alfa Films | false | false |
| 43 | 29 | Saw V | $190 | -80.4% | 2 | -4 | $95 | $1,047,003 | 11 | Walt Disney Pictures | false | false |
| 44 | 39 | Shara | $143 | -45.2% | 1 | - | $143 | $43,187 | 11 | Zeta Films | false | false |
| 45 | 41 | Mamma Mia! | $143 | -25.1% | 1 | - | $143 | $1,433,886 | 21 | United International Pictures | false | false |
| 46 | 42 | Days of Darkness | $143 | -25.1% | 1 | - | $143 | $15,248 | 13 | Alfa Films | false | false |
| 47 | 43 | The Magic Flute | $120 | -5.5% | 1 | - | $120 | $26,340 | 12 | Distribution Company | false | false |
| 48 | - | Tropic Thunder | $92 | - | 1 | - | $92 | $1,213,770 | 19 | United International Pictures | false | false |
| 49 | - | Café de los maestros | $50 | - | 1 | - | $50 | $95,274 | 29 | Alfa Films | false | false |
| 50 | - | Two Friends and a Burglar | $40 | - | 1 | - | $40 | $9,287 | 7 | Primer Plano Film Group | false | false |
| 51 | 27 | Ira & Abby | $34 | -97.6% | 1 | - | $34 | $42,939 | 5 | CDI Films | false | false |
| 52 | 40 | La leyenda | $32 | -87.6% | 1 | -1 | $32 | $215,276 | 8 | United International Pictures | false | false |
| 53 | 24 | Death Defying Acts | $31 | -98.4% | 1 | -6 | $31 | $118,814 | 7 | Alfa Films | false | false |
