| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | If I Were You 2 | $2,396,515 | - | 263 | - | $9,112 | $3,646,568 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Madagascar: Escape 2 Africa | $1,122,026 | -26.9% | 501 | -9 | $2,239 | $12,635,083 | 4 | Paramount Pictures International | false | false |
| 3 | 3 | Seven Pounds | $1,016,826 | -4.3% | 215 | +12 | $4,729 | $2,816,216 | 2 | Sony Pictures Releasing | false | false |
| 4 | 2 | Marley & Me | $876,279 | -21% | 172 | - | $5,094 | $2,821,153 | 2 | 20th Century Fox International | false | false |
| 5 | - | Bolt | $817,846 | - | 220 | - | $3,717 | $1,129,970 | 1 | Walt Disney Pictures | true | false |
| 6 | 4 | Twilight | $645,227 | -33.6% | 321 | - | $2,010 | $4,391,577 | 3 | Paris Filmes | false | false |
| 7 | 5 | Inkheart | $247,327 | -28.5% | 176 | +2 | $1,405 | $865,950 | 2 | PlayArte Pictures | false | false |
| 8 | 6 | Burn After Reading | $55,628 | -25.2% | 105 | +46 | $529 | $1,917,273 | 6 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Gomorrah | $43,949 | +3% | 24 | -3 | $1,831 | $182,038 | 3 | Paris Filmes | false | false |
| 10 | 9 | Vicky Cristina Barcelona | $39,111 | -2.1% | 35 | -3 | $1,117 | $2,245,498 | 8 | Imagem Filmes | false | false |
| 11 | 7 | Good | $35,891 | -35.4% | 26 | +3 | $1,380 | $131,014 | 2 | Imagem Filmes | false | false |
| 12 | 10 | Body of Lies | $25,863 | -32% | 50 | -15 | $517 | $1,565,073 | 6 | Warner Bros. | false | false |
| 13 | 13 | Café de los maestros | $16,007 | +12.9% | 8 | +6 | $2,000 | $39,124 | 2 | VideoFilmes | false | false |
| 14 | 12 | The Boy in the Striped Pajamas | $15,511 | -6.7% | 8 | - | $1,938 | $202,819 | 4 | Walt Disney Pictures | false | false |
| 15 | - | The Beautiful Person | $13,884 | - | 2 | - | $6,942 | $13,884 | 1 | Imovision | true | false |
| 16 | 17 | Be Kind Rewind | $13,848 | +46.2% | 7 | -4 | $1,978 | $126,881 | 4 | Europa Filmes | false | false |
| 17 | 11 | Transporter 3 | $12,065 | -59.1% | 34 | -21 | $354 | $607,599 | 4 | Imagem Filmes | false | false |
| 18 | 15 | Quantum of Solace | $6,586 | -48.3% | 34 | -16 | $193 | $7,364,286 | 9 | Sony Pictures Releasing | false | false |
| 19 | 14 | High School Musical 3: Senior Year | $6,513 | -51.7% | 61 | -50 | $106 | $5,498,881 | 11 | Walt Disney Pictures | false | false |
| 20 | 32 | Max Payne | $4,547 | +1,199.1% | 18 | +15 | $252 | $1,012,353 | 7 | 20th Century Fox International | false | false |
| 21 | 28 | Blindness | $3,917 | +489% | 11 | +5 | $356 | $3,291,019 | 17 | 20th Century Fox International | false | false |
| 22 | 18 | Romance | $3,635 | -38.7% | 20 | -12 | $181 | $850,939 | 8 | Walt Disney Pictures | false | false |
| 23 | 20 | Saw V | $2,734 | -6.9% | 16 | -12 | $170 | $2,425,234 | 10 | Walt Disney Pictures | false | false |
| 24 | 22 | The Duchess | $2,582 | -8.6% | 28 | +18 | $92 | $431,682 | 7 | Paramount Pictures International | false | false |
| 25 | 21 | Dan in Real Life | $2,218 | -24.4% | 11 | -3 | $201 | $818,857 | 10 | Europa Filmes | false | false |
| 26 | - | December | $2,073 | - | 7 | - | $296 | $73,934 | 7 | Europa Filmes | false | false |
| 27 | 23 | The Strangers | $1,971 | -17.8% | 15 | -7 | $131 | $1,000,982 | 7 | Paris Filmes | false | false |
| 28 | - | College | $1,446 | - | 8 | - | $180 | $539,363 | 5 | California Filmes | false | false |
| 29 | 26 | Leonera | $979 | +40.1% | 3 | - | $326 | $33,495 | 9 | Walt Disney Pictures | false | false |
| 30 | 27 | Deception | $785 | +17.5% | 7 | +2 | $112 | $211,820 | 5 | Paris Filmes | false | false |
| 31 | 19 | Once Upon a Time in Rio | $610 | -86.7% | 2 | -10 | $305 | $479,212 | 7 | Walt Disney Pictures | false | false |
| 32 | 30 | Traitor | $505 | -6% | 5 | -3 | $101 | $217,126 | 8 | PlayArte Pictures | false | false |
| 33 | 33 | The House Bunny | $483 | +102.1% | 3 | -1 | $161 | $319,391 | 13 | Sony Pictures Releasing | false | false |
| 34 | - | REC | $400 | - | 2 | - | $200 | $580,746 | 8 | California Filmes | false | false |
| 35 | 34 | Step Brothers | $395 | +168.7% | 3 | -1 | $131 | $217,279 | 11 | Sony Pictures Releasing | false | false |
| 36 | 31 | Nights in Rodanthe | $111 | -69.7% | 1 | -1 | $111 | $1,319,679 | 14 | Warner Bros. | false | false |
| 37 | 24 | Fly Me to the Moon 3D | $80 | -89.7% | 2 | -5 | $40 | $1,604,994 | 13 | PlayArte Pictures | false | false |
