| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Yes Man | $2,966,066 | - | 256 | - | $11,586 | $2,966,066 | 1 | Roadshow Films | true | false |
| 2 | 1 | The Curious Case of Benjamin Button | $2,123,609 | -6.7% | 251 | - | $8,460 | $5,975,252 | 2 | Warner Bros. | false | false |
| 3 | 3 | Bedtime Stories | $1,712,911 | -4% | 315 | -41 | $5,437 | $5,434,718 | 2 | Walt Disney Pictures | false | false |
| 4 | - | Bolt | $1,702,465 | - | 293 | - | $5,810 | $1,773,944 | 1 | Walt Disney Pictures | true | false |
| 5 | - | Marley & Me | $1,697,535 | - | 207 | - | $8,200 | $1,697,535 | 1 | 20th Century Fox International | true | false |
| 6 | 4 | Madagascar: Escape 2 Africa | $1,448,542 | -4.5% | 311 | -55 | $4,657 | $11,825,289 | 4 | Paramount Pictures International | false | false |
| 7 | 5 | Australia | $1,373,076 | +7.6% | 309 | -54 | $4,443 | $20,515,638 | 6 | 20th Century Fox International | false | false |
| 8 | 2 | The Day the Earth Stood Still | $1,164,691 | -46.3% | 257 | - | $4,531 | $4,533,370 | 2 | 20th Century Fox International | false | false |
| 9 | 6 | Twilight | $900,080 | -8.1% | 207 | -44 | $4,348 | $10,930,056 | 5 | - | false | false |
| 10 | 9 | Slumdog Millionaire | $488,312 | +52.1% | 33 | - | $14,797 | $1,491,710 | 3 | Icon Film Distribution | false | false |
| 11 | 7 | Quantum of Solace | $418,246 | -23.3% | 162 | -167 | $2,581 | $21,023,430 | 7 | Sony Pictures Releasing | false | false |
| 12 | 11 | Vicky Cristina Barcelona | $324,700 | +22.1% | 61 | +2 | $5,322 | $1,014,709 | 2 | Hopscotch Films | false | false |
| 13 | 12 | Frost/Nixon | $264,460 | +34.1% | 59 | - | $4,482 | $699,572 | 2 | Universal Pictures International (UPI) | false | false |
| 14 | 10 | High School Musical 3: Senior Year | $183,215 | -35.7% | 129 | -183 | $1,420 | $7,575,290 | 5 | Walt Disney Pictures | false | false |
| 15 | 13 | I've Loved You So Long | $178,280 | +53.1% | 25 | - | $7,131 | $545,015 | 2 | Palace Films | false | false |
| 16 | 8 | Four Christmases | $116,867 | -64% | 103 | -64 | $1,134 | $4,806,295 | 5 | Roadshow Films | false | false |
| 17 | 14 | Wild Ocean | $42,961 | +26.6% | 2 | - | $21,480 | $840,614 | 29 | IMAX | false | false |
| 18 | 15 | Burn After Reading | $38,090 | +63.2% | 18 | -23 | $2,116 | $6,837,518 | 12 | Universal Pictures International (UPI) | false | false |
| 19 | 17 | Santa vs. the Snowman 3D | $25,769 | +54.1% | 1 | -1 | $25,769 | $1,625,427 | 320 | IMAX | false | false |
| 20 | - | WALL·E | $25,252 | - | 7 | - | $3,607 | $14,165,390 | 18 | Walt Disney Pictures | false | false |
| 21 | 20 | The Dark Knight | $14,646 | +65.6% | 1 | -4 | $14,646 | $39,804,510 | 25 | Warner Bros. | false | false |
| 22 | - | U2 3D | $13,156 | - | 1 | - | $13,156 | $1,055,955 | 39 | Roadshow Films | false | false |
| 23 | - | Fly Me to the Moon 3D | $12,849 | - | 2 | - | $6,424 | $375,583 | 16 | IMAX | false | false |
| 24 | - | Welcome to the Sticks | $6,959 | - | 2 | - | $3,479 | $598,769 | 18 | Hopscotch Films | false | false |
| 25 | - | Haunted Castle | $6,742 | - | 1 | - | $6,742 | $3,724,149 | 381 | IMAX | false | false |
| 26 | 19 | Roman de gare | $5,192 | -56.5% | 3 | -2 | $1,730 | $253,590 | 9 | Arkles Entertainment | false | false |
| 27 | 16 | Rab Ne Bana Di Jodi | $4,434 | -78.3% | 5 | -9 | $886 | $336,797 | 4 | MG Distribution | false | false |
| 28 | - | In Bruges | $3,846 | - | 3 | - | $1,282 | $2,368,903 | 19 | Icon Film Distribution | false | false |
| 29 | 18 | City of Ember | $3,280 | -74.5% | 14 | -68 | $234 | $309,314 | 4 | Icon Film Distribution | false | false |
| 30 | - | African Adventure: Safari in the Okavango | $2,735 | - | 1 | - | $2,735 | $770,708 | 94 | IMAX | false | false |
| 31 | - | Nights in Rodanthe | $2,086 | - | 6 | - | $347 | $3,185,781 | 9 | Roadshow Films | false | false |
| 32 | - | The Wackness | $1,995 | - | 4 | - | $498 | $172,825 | 8 | Madman Entertainment | false | false |
| 33 | - | Hunger | $1,888 | - | 2 | - | $944 | $241,092 | 9 | Icon Film Distribution | false | false |
| 34 | - | Quarantine | $1,369 | - | 2 | - | $684 | $728,329 | 6 | Sony Pictures Releasing | false | false |
| 35 | - | It's a Free World... | $1,331 | - | 1 | - | $1,331 | $24,702 | 5 | Roadshow Films | false | false |
| 36 | - | Grand Canyon Adventure: River at Risk | $1,301 | - | 1 | - | $1,301 | $277,793 | 29 | IMAX | false | false |
| 37 | - | Man on Wire | $1,204 | - | 2 | - | $602 | $286,121 | 12 | Madman Entertainment | false | false |
| 38 | - | Brideshead Revisited | $168 | - | 1 | - | $168 | $997,107 | 11 | Icon Film Distribution | false | false |
