| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $16,602 | -41.9% | 10 | - | $1,660 | $120,286 | 3 | Taramount Film | false | false |
| 2 | 3 | The Day the Earth Stood Still | $8,919 | +22.1% | 7 | - | $1,274 | $40,324 | 3 | Tuck | false | false |
| 3 | 4 | Four Christmases | $7,129 | +3.8% | 4 | - | $1,782 | $17,832 | 2 | Tuck | false | false |
| 4 | 2 | Vicky Cristina Barcelona | $5,537 | -25.2% | 4 | - | $1,384 | $130,584 | 6 | N/A | false | false |
| 5 | 13 | Nights in Rodanthe | $3,217 | +1,069.8% | 6 | - | $536 | $33,197 | 7 | Tuck | false | false |
| 6 | - | Pride and Glory | $2,927 | - | 3 | - | $975 | $3,484 | 1 | Tuck | true | false |
| 7 | 7 | Body of Lies | $2,658 | -20.6% | 5 | - | $531 | $48,991 | 6 | Tuck | false | false |
| 8 | 9 | Bangkok Dangerous | $2,643 | -12.4% | 4 | - | $660 | $16,333 | 5 | N/A | false | false |
| 9 | 6 | The Women | $2,604 | -23.3% | 2 | - | $1,302 | $18,526 | 2 | N/A | false | false |
| 10 | 10 | High School Musical 3: Senior Year | $2,103 | -11% | 4 | - | $525 | $28,098 | 4 | Taramount Film | false | false |
| 11 | 5 | Quantum of Solace | $1,949 | -52.3% | 8 | - | $243 | $183,146 | 8 | Tuck | false | false |
| 12 | 8 | Mirrors | $1,819 | -42.9% | 4 | - | $454 | $35,728 | 13 | Tuck | false | false |
| 13 | 11 | Christmas Story | $1,457 | +87.3% | 5 | - | $291 | $9,905 | 4 | N/A | false | false |
| 14 | 21 | Max Payne | $563 | +539.8% | 5 | - | $112 | $36,693 | 11 | Tuck | false | false |
| 15 | 16 | The House Bunny | $218 | +56.8% | 5 | - | $43 | $50,067 | 10 | Tuck | false | false |
| 16 | 15 | Deception | $172 | -14.9% | 2 | - | $86 | $8,545 | 4 | N/A | false | false |
| 17 | 14 | Quarantine | $146 | -31.5% | 3 | - | $48 | $5,051 | 5 | Tuck | false | false |
| 18 | - | Kung Fu Panda | $111 | - | 7 | - | $15 | $97,301 | 26 | Taramount Film | false | false |
| 19 | 17 | Mamma Mia! | $95 | -27.5% | 7 | - | $13 | $124,924 | 17 | Taramount Film | false | false |
| 20 | 19 | Pineapple Express | $65 | -31.6% | 2 | -1 | $32 | $2,867 | 6 | Tuck | false | false |
| 21 | 20 | Righteous Kill | $21 | -76.4% | 2 | - | $10 | $21,244 | 7 | N/A | false | false |
| 22 | 25 | Eagle Eye | $18 | -48.6% | 4 | - | $4 | $13,995 | 6 | Taramount Film | false | false |
| 23 | - | Journey to the Center of the Earth | $14 | - | 4 | - | $3 | $31,572 | 17 | Tuck | false | false |
| 24 | 29 | Nim's Island | $7 | -41.7% | 2 | - | $3 | $7,400 | 9 | N/A | false | false |
