Domestic 2008 Weekend 48
November 26-30, 2008 - Thanksgiving 5-Day weekend (US)
Key:New This Week
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | - | Four Christmases | $46,054,468 | - | 3,310 | - | $13,913 | $46,054,468 | 1 | Warner Bros. |
| 2 | - | Twilight | $39,540,889 | - | 3,425 | - | $11,544 | $119,706,509 | 2 | Summit Entertainment |
| 3 | - | Bolt | $35,995,522 | - | 3,654 | - | $9,850 | $66,848,840 | 2 | Walt Disney Studios Motion Pictures |
| 4 | - | Quantum of Solace | $27,487,933 | - | 3,501 | - | $7,851 | $141,418,534 | 3 | Sony Pictures Releasing |
| 5 | - | Australia | $20,004,456 | - | 2,642 | - | $7,571 | $20,004,456 | 1 | Twentieth Century Fox |
| 6 | - | Madagascar: Escape 2 Africa | $19,154,953 | - | 3,709 | - | $5,164 | $159,066,369 | 4 | DreamWorks |
| 7 | - | Transporter 3 | $18,230,758 | - | 2,626 | - | $6,942 | $18,230,758 | 1 | Lionsgate |
| 8 | - | Role Models | $7,693,480 | - | 2,195 | - | $3,505 | $57,780,820 | 4 | Universal Pictures |
| 9 | - | The Boy in the Striped Pajamas | $2,199,240 | - | 582 | - | $3,778 | $5,169,495 | 4 | Miramax |
| 10 | - | Milk | $1,941,472 | - | 36 | - | $53,929 | $1,941,472 | 1 | Focus Features |
| 11 | - | Slumdog Millionaire | $1,767,019 | - | 49 | - | $36,061 | $3,544,374 | 3 | - |
| 12 | - | Changeling | $1,601,140 | - | 1,010 | - | $1,585 | $33,849,632 | 6 | Universal Pictures |
| 13 | - | High School Musical 3: Senior Year | $1,445,033 | - | 1,385 | - | $1,043 | $88,751,254 | 6 | Walt Disney Studios Motion Pictures |
| 14 | - | Zack and Miri Make a Porno | $751,015 | - | 437 | - | $1,718 | $30,439,806 | 5 | The Weinstein Company |
| 15 | - | The Secret Life of Bees | $726,486 | - | 490 | - | $1,482 | $36,652,652 | 7 | - |
| 16 | - | Soul Men | $598,976 | - | 335 | - | $1,787 | $11,652,750 | 4 | - |
| 17 | - | Fireproof | $585,524 | - | 486 | - | $1,204 | $32,306,871 | 10 | The Samuel Goldwyn Company |
| 18 | - | The Dark Knight | $475,640 | - | 322 | - | $1,477 | $530,258,989 | 20 | Warner Bros. |
| 19 | - | Happy-Go-Lucky | $365,115 | - | 202 | - | $1,807 | $2,641,426 | 8 | Miramax |
| 20 | - | Eagle Eye | $339,984 | - | 325 | - | $1,046 | $100,232,865 | 10 | DreamWorks |
| 21 | - | The Polar Express 2008 IMAX Release | $184,845 | - | 21 | - | $8,802 | $246,992 | 2 | Warner Bros. |
| 22 | - | Saw V | $161,232 | - | 177 | - | $910 | $56,652,813 | 6 | Lionsgate |
| 23 | - | Righteous Kill | $150,981 | - | 197 | - | $766 | $39,983,772 | 12 | Overture Films |
| 24 | - | Igor | $137,704 | - | 179 | - | $769 | $19,242,800 | 11 | Metro-Goldwyn-Mayer (MGM) |
| 25 | - | Body of Lies | $114,440 | - | 106 | - | $1,079 | $38,900,252 | 8 | Warner Bros. |
| 26 | - | Burn After Reading | $112,633 | - | 97 | - | $1,161 | $60,169,788 | 12 | Focus Features |
| 27 | - | Max Payne | $108,118 | - | 161 | - | $671 | $40,438,648 | 7 | Twentieth Century Fox |
| 28 | - | Appaloosa | $92,927 | - | 127 | - | $731 | $19,929,043 | 11 | Warner Bros. |
| 29 | - | The Haunting of Molly Hartley | $92,412 | - | 123 | - | $751 | $13,350,177 | 5 | Freestyle Releasing |
| 30 | - | Religulous | $84,378 | - | 61 | - | $1,383 | $12,889,735 | 9 | Lionsgate |
| 31 | - | W. | $73,894 | - | 55 | - | $1,343 | $25,517,500 | 7 | Lionsgate |
| 32 | - | City of Ember | $71,043 | - | 111 | - | $640 | $7,743,762 | 8 | Twentieth Century Fox |
| 33 | - | Deep Sea | $66,284 | - | 9 | - | $7,364 | $37,021,878 | 144 | Warner Bros. |
| 34 | - | The Duchess | $61,228 | - | 78 | - | $784 | $13,759,842 | 11 | Paramount Vantage |
| 35 | - | Vicky Cristina Barcelona | $53,436 | - | 18 | - | $2,968 | $22,478,183 | 16 | - |
| 36 | - | RocknRolla | $50,589 | - | 52 | - | $972 | $5,582,509 | 8 | Warner Bros. |
| 37 | - | Nights in Rodanthe | $43,012 | - | 86 | - | $500 | $41,528,121 | 10 | Warner Bros. |
| 38 | - | Journey to the Center of the Earth | $27,996 | - | 63 | - | $444 | $101,689,940 | 21 | Warner Bros. |
| 39 | - | Noah's Arc: Jumping the Broom | $24,883 | - | 4 | - | $6,220 | $511,955 | 6 | - |
| 40 | - | Pride and Glory | $18,199 | - | 33 | - | $551 | $15,649,224 | 6 | Warner Bros. |
| 41 | - | Sex Drive | $17,755 | - | 52 | - | $341 | $8,396,942 | 7 | Summit Entertainment |
| 42 | - | Repo! The Genetic Opera | $13,863 | - | 6 | - | $2,310 | $124,650 | 4 | Lionsgate |
| 43 | - | My Name Is Bruce | $13,284 | - | 1 | - | $13,284 | $119,909 | 5 | Image Entertainment |
| 44 | - | Were the World Mine | $11,214 | - | 3 | - | $3,738 | $36,962 | 5 | - |
| 45 | - | How to Lose Friends & Alienate People | $7,313 | - | 29 | - | $252 | $2,768,010 | 9 | Metro-Goldwyn-Mayer (MGM) |
| 46 | - | Hounddog | $3,825 | - | 2 | - | $1,912 | $122,704 | 11 | Empire Pictures Inc. |
| 47 | - | I.O.U.S.A. | $3,406 | - | 5 | - | $681 | $804,568 | 15 | Roadside Attractions |
| 48 | - | The First Basket | $1,759 | - | 3 | - | $586 | $18,995 | 5 | - |
| 49 | - | The Alphabet Killer | $1,714 | - | 2 | - | $857 | $26,887 | 4 | Anchor Bay Films |
| 50 | - | House | $1,024 | - | 14 | - | $73 | $569,792 | 4 | Roadside Attractions |
| 51 | - | Lola Montès | $798 | - | 1 | - | $798 | $85,486 | - | Rialto Pictures |
| 52 | - | The Other End of the Line | $782 | - | 2 | - | $391 | $115,024 | 5 | Metro-Goldwyn-Mayer (MGM) |
| 53 | - | Eden | $435 | - | 2 | - | $217 | $8,222 | - | Liberation Entertainment |
