Domestic 2008 Weekend 48
November 27-30, 2008 - Thanksgiving 4-Day weekend (US)
Key:New This Week
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | - | Four Christmases | $39,972,704 | - | 3,310 | - | $12,076 | $46,054,468 | 1 | Warner Bros. |
| 2 | - | Twilight | $31,576,008 | - | 3,425 | - | $9,219 | $119,706,509 | 2 | Summit Entertainment |
| 3 | - | Bolt | $30,903,340 | - | 3,654 | - | $8,457 | $66,848,840 | 2 | Walt Disney Studios Motion Pictures |
| 4 | - | Quantum of Solace | $23,420,355 | - | 3,501 | - | $6,689 | $141,418,534 | 3 | Sony Pictures Releasing |
| 5 | - | Australia | $17,735,898 | - | 2,642 | - | $6,713 | $20,004,456 | 1 | Twentieth Century Fox |
| 6 | - | Madagascar: Escape 2 Africa | $16,417,693 | - | 3,709 | - | $4,426 | $159,066,369 | 4 | DreamWorks |
| 7 | - | Transporter 3 | $14,905,996 | - | 2,626 | - | $5,676 | $18,230,758 | 1 | Lionsgate |
| 8 | - | Role Models | $6,519,155 | - | 2,195 | - | $2,970 | $57,780,820 | 4 | Universal Pictures |
| 9 | - | The Boy in the Striped Pajamas | $1,948,824 | - | 582 | - | $3,348 | $5,169,495 | 4 | Miramax |
| 10 | - | Milk | $1,672,985 | - | 36 | - | $46,471 | $1,941,472 | 1 | Focus Features |
| 11 | - | Slumdog Millionaire | $1,566,275 | - | 49 | - | $31,964 | $3,544,374 | 3 | - |
| 12 | - | Changeling | $1,419,340 | - | 1,010 | - | $1,405 | $33,849,632 | 6 | Universal Pictures |
| 13 | - | High School Musical 3: Senior Year | $1,188,997 | - | 1,385 | - | $858 | $88,751,254 | 6 | Walt Disney Studios Motion Pictures |
| 14 | - | The Secret Life of Bees | $649,913 | - | 490 | - | $1,326 | $36,652,652 | 7 | - |
| 15 | - | Zack and Miri Make a Porno | $638,283 | - | 437 | - | $1,460 | $30,439,806 | 5 | The Weinstein Company |
| 16 | - | Soul Men | $546,460 | - | 335 | - | $1,631 | $11,652,750 | 4 | - |
| 17 | - | Fireproof | $508,632 | - | 486 | - | $1,046 | $32,306,871 | 10 | The Samuel Goldwyn Company |
| 18 | - | The Dark Knight | $406,387 | - | 322 | - | $1,262 | $530,258,989 | 20 | Warner Bros. |
| 19 | - | Happy-Go-Lucky | $328,194 | - | 202 | - | $1,624 | $2,641,426 | 8 | Miramax |
| 20 | - | Eagle Eye | $297,431 | - | 325 | - | $915 | $100,232,865 | 10 | DreamWorks |
| 21 | - | The Polar Express 2008 IMAX Release | $165,550 | - | 21 | - | $7,883 | $246,992 | 2 | Warner Bros. |
| 22 | - | Saw V | $139,923 | - | 177 | - | $790 | $56,652,813 | 6 | Lionsgate |
| 23 | - | Righteous Kill | $130,164 | - | 197 | - | $660 | $39,983,772 | 12 | Overture Films |
| 24 | - | Igor | $122,150 | - | 179 | - | $682 | $19,242,800 | 11 | Metro-Goldwyn-Mayer (MGM) |
| 25 | - | Burn After Reading | $100,495 | - | 97 | - | $1,036 | $60,169,788 | 12 | Focus Features |
| 26 | - | Body of Lies | $100,394 | - | 106 | - | $947 | $38,900,252 | 8 | Warner Bros. |
| 27 | - | Max Payne | $94,317 | - | 161 | - | $585 | $40,438,648 | 7 | Twentieth Century Fox |
| 28 | - | The Haunting of Molly Hartley | $81,950 | - | 123 | - | $666 | $13,350,177 | 5 | Freestyle Releasing |
| 29 | - | Appaloosa | $79,359 | - | 127 | - | $624 | $19,929,043 | 11 | Warner Bros. |
| 30 | - | Religulous | $72,360 | - | 61 | - | $1,186 | $12,889,735 | 9 | Lionsgate |
| 31 | - | W. | $65,584 | - | 55 | - | $1,192 | $25,517,500 | 7 | Lionsgate |
| 32 | - | City of Ember | $62,108 | - | 111 | - | $559 | $7,743,762 | 8 | Twentieth Century Fox |
| 33 | - | Deep Sea | $56,702 | - | 9 | - | $6,300 | $37,021,878 | 144 | Warner Bros. |
| 34 | - | The Duchess | $53,370 | - | 78 | - | $684 | $13,759,842 | 11 | Paramount Vantage |
| 35 | - | Vicky Cristina Barcelona | $48,539 | - | 18 | - | $2,696 | $22,478,183 | 16 | - |
| 36 | - | RocknRolla | $44,360 | - | 52 | - | $853 | $5,582,509 | 8 | Warner Bros. |
| 37 | - | Nights in Rodanthe | $36,916 | - | 86 | - | $429 | $41,528,121 | 10 | Warner Bros. |
| 38 | - | Journey to the Center of the Earth | $23,343 | - | 63 | - | $370 | $101,689,940 | 21 | Warner Bros. |
| 39 | - | Noah's Arc: Jumping the Broom | $22,268 | - | 4 | - | $5,567 | $511,955 | 6 | - |
| 40 | - | Pride and Glory | $15,324 | - | 33 | - | $464 | $15,649,224 | 6 | Warner Bros. |
| 41 | - | Sex Drive | $14,491 | - | 52 | - | $278 | $8,396,942 | 7 | Summit Entertainment |
| 42 | - | My Name Is Bruce | $13,284 | - | 1 | - | $13,284 | $119,909 | 5 | Image Entertainment |
| 43 | - | Repo! The Genetic Opera | $12,076 | - | 6 | - | $2,012 | $124,650 | 4 | Lionsgate |
| 44 | - | Were the World Mine | $8,883 | - | 3 | - | $2,961 | $36,962 | 5 | - |
| 45 | - | How to Lose Friends & Alienate People | $6,417 | - | 29 | - | $221 | $2,768,010 | 9 | Metro-Goldwyn-Mayer (MGM) |
| 46 | - | Hounddog | $3,825 | - | 2 | - | $1,912 | $122,704 | 11 | Empire Pictures Inc. |
| 47 | - | I.O.U.S.A. | $3,259 | - | 5 | - | $651 | $804,568 | 15 | Roadside Attractions |
| 48 | - | The Alphabet Killer | $1,546 | - | 2 | - | $773 | $26,887 | 4 | Anchor Bay Films |
| 49 | - | The First Basket | $1,354 | - | 3 | - | $451 | $18,995 | 5 | - |
| 50 | - | House | $871 | - | 14 | - | $62 | $569,792 | 4 | Roadside Attractions |
| 51 | - | The Other End of the Line | $688 | - | 2 | - | $344 | $115,024 | 5 | Metro-Goldwyn-Mayer (MGM) |
| 52 | - | Lola Montès | $434 | - | 1 | - | $434 | $85,486 | - | Rialto Pictures |
| 53 | - | Eden | $217 | - | 2 | - | $108 | $8,222 | - | Liberation Entertainment |
