| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Loft | $467,399 | -10.6% | 42 | - | $11,128 | $6,087,235 | 6 | Independent Films | false | false |
| 2 | - | Twilight | $354,047 | - | 52 | - | $6,808 | $354,047 | 1 | Belga Films | true | false |
| 3 | 2 | Quantum of Solace | $293,543 | -32.4% | 97 | - | $3,026 | $4,096,259 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | Body of Lies | $187,245 | -29.6% | 50 | - | $3,744 | $508,946 | 2 | Warner Bros. | false | false |
| 5 | - | Max Payne | $165,615 | - | 35 | - | $4,731 | $165,615 | 1 | 20th Century Fox International | true | false |
| 6 | 4 | Changeling | $127,804 | -12% | 33 | - | $3,872 | $602,226 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | High School Musical 3: Senior Year | $80,979 | -33.7% | 64 | -5 | $1,265 | $2,271,328 | 5 | Walt Disney Pictures | false | false |
| 8 | 6 | Public Enemy | $63,009 | -39.2% | 19 | -2 | $3,316 | $188,804 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | - | Nights in Rodanthe | $62,245 | - | 25 | - | $2,489 | $91,503 | 1 | Warner Bros. | true | false |
| 10 | - | The Bank Job | $56,470 | - | 15 | - | $3,764 | $62,511 | 1 | Benelux Film Distributors | true | false |
| 11 | 7 | Vicky Cristina Barcelona | $48,552 | -40% | 20 | -8 | $2,427 | $869,513 | 5 | Cinéart | false | false |
| 12 | 9 | Le vilain | $40,474 | -20.2% | 13 | - | $3,113 | $182,614 | 3 | Victory Productions | false | false |
| 13 | 8 | Journey to the Center of the Earth | $38,527 | -33.5% | 11 | - | $3,502 | $217,251 | 3 | Warner Bros. | false | false |
| 14 | 12 | The Ottoman Republic | $28,966 | -21.2% | 6 | - | $4,827 | $79,415 | 2 | Maxximum Film und Kunst GmbH | false | false |
| 15 | 10 | Space Chimps | $26,956 | -37.1% | 47 | -5 | $573 | $1,149,178 | 6 | Belga Films | false | false |
| 16 | 11 | Anubis en het Pad der 7 Zonden | $25,383 | -33.4% | 29 | -2 | $875 | $1,287,128 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | - | Musée haut, musée bas | $24,536 | - | 6 | - | $4,089 | $27,074 | 1 | Cinéart | true | false |
| 18 | - | Brideshead Revisited | $19,580 | - | 11 | - | $1,780 | $20,495 | 1 | Cinéart | true | false |
| 19 | 13 | RocknRolla | $15,745 | -53.2% | 10 | -2 | $1,574 | $60,561 | 2 | Universal Pictures International (UPI) | false | false |
| 20 | 19 | Sinterklaas en het geheim van het grote boek | $15,283 | -21.7% | 7 | - | $2,183 | $71,436 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 21 | 21 | The Class | $14,076 | -10.9% | 19 | -1 | $740 | $677,460 | 9 | Cinéart | false | false |
| 22 | 22 | Crime Is Our Business | $12,616 | -4.5% | 6 | - | $2,102 | $47,739 | 3 | Cinéart | false | false |
| 23 | 17 | Mesrine: Killer Instinct | $12,153 | -43.1% | 16 | -5 | $759 | $513,462 | 6 | A-Film Distribution | false | false |
| 24 | - | Nowhere Man | $11,273 | - | 8 | - | $1,409 | $11,589 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 25 | - | Baby Blues | $10,885 | - | 8 | - | $1,360 | $13,606 | 1 | Les Films de l'Elysée | true | false |
| 26 | - | Rachel Getting Married | $10,656 | - | 3 | - | $3,552 | $10,656 | 1 | Sony Pictures Releasing | true | false |
| 27 | 15 | The Accidental Husband | $10,479 | -61.1% | 12 | -13 | $873 | $353,015 | 4 | Belga Films | false | false |
| 28 | 18 | Sex Drive | $9,566 | -54.4% | 14 | -11 | $683 | $426,512 | 5 | Belga Films | false | false |
| 29 | 20 | Mamma Mia! | $9,040 | -45.1% | 25 | -12 | $361 | $3,478,937 | 12 | Universal Pictures International (UPI) | false | false |
| 30 | 32 | Welcome to the Sticks | $8,764 | +22.5% | 9 | - | $973 | $8,611,898 | 40 | Alternative Films | false | false |
| 31 | 14 | Righteous Kill | $8,158 | -70.9% | 28 | - | $291 | $577,569 | 5 | Benelux Film Distributors | false | false |
| 32 | 26 | Seraphine | $7,912 | -4% | 6 | -1 | $1,318 | $126,713 | 6 | Cinéart | false | false |
| 33 | 16 | Bouquet final | $7,666 | -67.7% | 12 | -4 | $638 | $99,298 | 3 | Belga Films | false | false |
| 34 | 23 | Home | $6,557 | -25.5% | 6 | - | $1,092 | $40,018 | 3 | Benelux Film Distributors | false | false |
| 35 | 31 | WALL·E | $4,046 | -43.5% | 6 | -13 | $674 | $4,027,255 | 18 | Walt Disney Pictures | false | false |
| 36 | 36 | Elegy | $4,037 | -21.1% | 8 | - | $504 | $135,041 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 37 | 37 | Kung Fu Panda | $3,520 | -30.2% | 8 | -7 | $440 | $4,795,596 | 21 | Universal Pictures International (UPI) | false | false |
| 38 | 24 | My Best Friend's Girl | $3,148 | -64% | 1 | -5 | $3,148 | $431,202 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 39 | 29 | Eagle Eye | $2,986 | -61.5% | 2 | -4 | $1,493 | $1,366,497 | 9 | Universal Pictures International (UPI) | false | false |
| 40 | - | Cloud 9 | $2,806 | - | 3 | - | $935 | $10,441 | 1 | Centre national du cinéma et de l'image animée (CNC) | true | false |
| 41 | 43 | Modern Life | $2,804 | -5.2% | 2 | +1 | $1,402 | $17,774 | 4 | Benelux Film Distributors | false | false |
| 42 | - | The Edge of Love | $2,684 | - | 2 | - | $1,342 | $5,583 | 1 | Belga Films | true | false |
| 43 | 27 | Avanak Kuzenler | $2,660 | -67.6% | 2 | -2 | $1,330 | $42,003 | 3 | Maxximum Film und Kunst GmbH | false | false |
| 44 | 39 | W. | $2,381 | -47.8% | 3 | -3 | $793 | $124,302 | 5 | Paradiso Entertainment | false | false |
| 45 | 44 | Death Race | $1,938 | -26.3% | 1 | -6 | $1,938 | $532,133 | 8 | Universal Pictures International (UPI) | false | false |
| 46 | 41 | Hunger | $1,836 | -45.6% | 5 | -1 | $367 | $21,276 | 3 | Paradiso Entertainment | false | false |
| 47 | 60 | Moscow, Belgium | $1,647 | +454.5% | 2 | - | $823 | $1,869,803 | 44 | Kinepolis Film Distribution (KFD) | false | false |
| 48 | - | The Black Balloon | $1,185 | - | 2 | - | $592 | $1,185 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 49 | 58 | Blindness | $1,176 | +246.9% | 8 | +3 | $147 | $165,761 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 50 | 55 | Happy-Go-Lucky | $1,081 | +98.7% | 10 | +2 | $108 | $212,880 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 51 | 49 | Go Fast | $837 | -36.4% | 1 | - | $837 | $333,519 | 9 | Belga Films | false | false |
| 52 | 45 | Cut Loose | $808 | -67% | 2 | -10 | $404 | $607,070 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 53 | 28 | Baby Mama | $776 | -90.4% | 2 | -3 | $388 | $9,839 | 2 | Universal Pictures International (UPI) | false | false |
| 54 | 56 | A French Gigolo | $681 | +53.4% | 2 | -1 | $340 | $165,574 | 8 | Benelux Film Distributors | false | false |
| 55 | 38 | Hellboy II: The Golden Army | $542 | -88.2% | 4 | -11 | $135 | $605,560 | 6 | Universal Pictures International (UPI) | false | false |
| 56 | 62 | Tricks | $446 | +214.1% | 1 | - | $446 | $4,502 | 5 | Benelux Film Distributors | false | false |
| 57 | 61 | Eldorado | $396 | +47.2% | 2 | - | $198 | $364,903 | 26 | Benelux Film Distributors | false | false |
| 58 | - | Versailles | $348 | - | 1 | - | $348 | $42,956 | 15 | Benelux Film Distributors | false | false |
| 59 | 25 | Pineapple Express | $309 | -96.4% | 2 | -3 | $154 | $10,849 | 2 | Sony Pictures Releasing | false | false |
| 60 | 59 | The Zone | $247 | -19.3% | 2 | -1 | $123 | $58,637 | 10 | Paradiso Entertainment | false | false |
| 61 | 54 | The Wave | $35 | -94% | 1 | -2 | $35 | $41,062 | 6 | Paradiso Entertainment | false | false |
