| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar: Escape 2 Africa | $621,312 | - | 27 | - | $23,011 | $621,312 | 1 | N/A | true | false |
| 2 | - | Outlander | $153,058 | - | 19 | - | $8,055 | $153,058 | 1 | N/A | true | false |
| 3 | 1 | Body of Lies | $140,955 | -56.2% | 18 | -2 | $7,830 | $556,231 | 2 | N/A | false | false |
| 4 | 2 | Saw V | $72,024 | -71.1% | 20 | - | $3,601 | $375,800 | 2 | N/A | false | false |
| 5 | - | A Prueba De Hombres | $54,966 | - | 14 | - | $3,926 | $54,966 | 1 | N/A | true | false |
| 6 | 3 | Quantum of Solace | $51,576 | -63.5% | 7 | -8 | $7,368 | $1,875,455 | 4 | N/A | false | false |
| 7 | - | The Duchess | $44,767 | - | 8 | - | $5,595 | $44,767 | 1 | N/A | true | false |
| 8 | - | The Deaths of Ian Stone | $43,319 | - | 12 | - | $3,609 | $43,319 | 1 | N/A | true | false |
| 9 | - | Elegy | $17,099 | - | 10 | - | $1,709 | $17,099 | 1 | N/A | true | false |
| 10 | 5 | Ghost Town | $7,307 | -81.5% | 4 | -12 | $1,826 | $58,786 | 2 | N/A | false | false |
| 11 | 8 | Pineapple Express | $3,366 | -90.1% | 3 | -9 | $1,122 | $52,222 | 2 | N/A | false | false |
| 12 | 10 | High School Musical 3: Senior Year | $3,325 | -61.8% | 2 | -1 | $1,662 | $640,432 | 6 | Walt Disney Pictures | false | false |
| 13 | 4 | Open Season 2 | $3,263 | -93.8% | 5 | -11 | $652 | $172,485 | 3 | N/A | false | false |
| 14 | 15 | Nights in Rodanthe | $2,850 | -5.8% | 1 | - | $2,850 | $75,294 | 3 | N/A | false | false |
| 15 | 7 | Hero Wanted | $2,827 | -92% | 2 | -17 | $1,413 | $258,025 | 3 | N/A | false | false |
| 16 | 9 | Over Her Dead Body | $2,235 | -86.5% | 1 | -13 | $2,235 | $95,173 | 3 | N/A | false | false |
| 17 | 12 | Eagle Eye | $1,869 | -68.3% | 1 | - | $1,869 | $1,085,615 | 8 | N/A | false | false |
| 18 | 6 | Igor | $1,541 | -95.7% | 7 | -5 | $220 | $42,434 | 2 | N/A | false | false |
| 19 | 11 | Bangkok Dangerous | $603 | -90.9% | 1 | -2 | $603 | $646,154 | 5 | N/A | false | false |
| 20 | 20 | Space Chimps | $114 | -82.3% | 1 | - | $114 | $177,135 | 18 | N/A | false | false |
| 21 | 18 | Dragon Hunters | $86 | -93.9% | 1 | - | $86 | $129,636 | 9 | N/A | false | false |
