| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar: Escape 2 Africa | $1,042,698 | - | 185 | - | $5,636 | $1,461,762 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Quantum of Solace | $1,013,125 | -35.3% | 135 | - | $7,504 | $5,657,227 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | Body of Lies | $264,830 | - | 60 | - | $4,413 | $290,532 | 1 | Warner Bros. | true | false |
| 4 | 4 | Sinterklaas en het geheim van het grote boek | $263,870 | +46.2% | 101 | - | $2,612 | $1,890,098 | 7 | RCV Film Distribution | false | false |
| 5 | 2 | Bride Flight | $183,824 | -22.4% | 96 | -1 | $1,914 | $2,544,050 | 6 | A-Film Distribution | false | false |
| 6 | 3 | Burn After Reading | $131,287 | -39.6% | 46 | +1 | $2,854 | $1,355,209 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | Anubis en het Pad der 7 Zonden | $73,383 | -31.9% | 106 | -6 | $692 | $4,327,455 | 7 | Independent Films | false | false |
| 8 | - | The Baader Meinhof Complex | $47,143 | - | 27 | - | $1,746 | $57,119 | 1 | A-Film Distribution | true | false |
| 9 | 7 | Radeloos | $44,913 | -38% | 82 | -16 | $547 | $2,386,231 | 8 | RCV Film Distribution | false | false |
| 10 | 8 | Nights in Rodanthe | $40,445 | -42.8% | 36 | - | $1,123 | $153,120 | 2 | Warner Bros. | false | false |
| 11 | - | The Ottoman Republic | $34,948 | - | - | - | - | $34,948 | 1 | N/A | true | false |
| 12 | 9 | My Best Friend's Girl | $34,773 | -46% | 39 | -20 | $891 | $1,156,725 | 7 | RCV Film Distribution | false | false |
| 13 | - | Friendship | $31,605 | - | - | - | - | $80,921 | 2 | N/A | false | false |
| 14 | 6 | Eagle Eye | $29,628 | -63.4% | 41 | -20 | $722 | $1,840,200 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | - | Blindness | $28,488 | - | 17 | - | $1,675 | $55,170 | 1 | RCV Film Distribution | true | false |
| 16 | 10 | How to Lose Friends & Alienate People | $27,981 | -51.5% | 24 | - | $1,165 | $125,681 | 2 | RCV Film Distribution | false | false |
| 17 | 13 | Mamma Mia! | $20,136 | -17.9% | 47 | -18 | $428 | $9,715,030 | 19 | Universal Pictures International (UPI) | false | false |
| 18 | 14 | Boy A | $18,572 | -17.2% | 10 | - | $1,857 | $59,638 | 2 | Cinemien | false | false |
| 19 | 15 | Welcome to the Sticks | $17,108 | -14.6% | 14 | - | $1,222 | $401,282 | 11 | Paradiso Entertainment | false | false |
| 20 | 11 | RocknRolla | $13,248 | -68.3% | 19 | -7 | $697 | $512,850 | 5 | Warner Bros. | false | false |
| 21 | 18 | Cloud 9 | $9,606 | -7.8% | 10 | - | $960 | $53,115 | 3 | - | false | false |
| 22 | - | Moscow, Belgium | $9,302 | - | 10 | - | $930 | $159,857 | 8 | RCV Film Distribution | false | false |
