| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Quantum of Solace | $2,300,082 | - | 504 | - | $4,563 | $2,300,082 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | X-mas, Inc. | $867,948 | - | 600 | - | $1,446 | $867,948 | 1 | Warner Bros. | true | false |
| 3 | 1 | High School Musical 3: Senior Year | $502,520 | -50.7% | 409 | -2 | $1,228 | $4,066,131 | 3 | Walt Disney Pictures | false | false |
| 4 | 3 | Mr. Magorium's Wonder Emporium | $239,281 | -39.2% | 202 | -1 | $1,184 | $758,325 | 2 | Zima Entertainment | false | false |
| 5 | 2 | Pride and Glory | $205,928 | -51% | 187 | -13 | $1,101 | $828,540 | 2 | Gussi Films | false | false |
| 6 | 6 | Burn After Reading | $130,432 | -37.1% | 155 | -30 | $841 | $1,696,033 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | 10 | The House Bunny | $123,021 | -1.1% | 131 | -10 | $939 | $1,080,487 | 4 | Sony Pictures Releasing | false | false |
| 8 | 4 | Death Race | $121,831 | -50.1% | 146 | -49 | $834 | $967,201 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 24 | Blindness | $103,563 | +142.8% | 122 | +72 | $848 | $855,176 | 5 | 20th Century Fox International | false | false |
| 10 | - | Impy's Island | $96,749 | - | 74 | - | $1,307 | $96,749 | 1 | Gussi Films | true | false |
| 11 | 5 | Beverly Hills Chihuahua | $94,720 | -58.3% | 199 | -152 | $475 | $7,530,500 | 7 | Walt Disney Pictures | false | false |
| 12 | 7 | Max Payne | $75,046 | -48.1% | 144 | -73 | $521 | $1,389,135 | 4 | 20th Century Fox International | false | false |
| 13 | 12 | Under the Salt | $68,305 | -43.1% | 139 | -35 | $491 | $1,596,367 | 5 | Warner Bros. | false | false |
| 14 | 8 | Saw V | $65,609 | -47.7% | 84 | -36 | $781 | $530,046 | 3 | Walt Disney Pictures | false | false |
| 15 | 11 | The Strangers | $59,781 | -50.7% | 72 | -40 | $830 | $2,306,555 | 9 | Videocine | false | false |
| 16 | 9 | My Mom's New Boyfriend | $55,221 | -55.9% | 93 | -59 | $593 | $1,160,360 | 6 | Zima Entertainment | false | false |
| 17 | 13 | The Bank Job | $54,298 | -52.4% | 63 | -16 | $861 | $1,649,129 | 12 | Gussi Films | false | false |
| 18 | 14 | Deception | $52,373 | -53.9% | 77 | -21 | $680 | $234,359 | 2 | Corazón Films | false | false |
| 19 | 18 | Nights in Rodanthe | $45,611 | -39.4% | 63 | -20 | $723 | $1,834,912 | 7 | Warner Bros. | false | false |
| 20 | 16 | The Air I Breathe | $39,126 | -53.7% | 69 | -44 | $567 | $641,777 | 5 | Videocine | false | false |
| 21 | 17 | REC | $38,275 | -53.6% | 41 | -46 | $933 | $5,189,300 | 12 | Videocine | false | false |
| 22 | 20 | Space Chimps | $35,737 | -34.5% | 79 | -55 | $452 | $512,675 | 4 | Corazón Films | false | false |
| 23 | - | The Last Legion | $31,149 | - | 43 | - | $724 | $827,621 | 12 | Zima Entertainment | false | false |
| 24 | - | Donkey Xote | $30,518 | - | 44 | - | $693 | $2,525,400 | 10 | Videocine | false | false |
| 25 | 19 | Traitor | $26,323 | -63.5% | 78 | -20 | $337 | $492,426 | 5 | Gussi Films | false | false |
| 26 | - | Apartment 1303 | $24,828 | - | 36 | - | $689 | $108,626 | 5 | Alphaville | false | false |
| 27 | 30 | Rogue | $24,290 | -5.5% | 33 | -6 | $736 | $252,453 | 9 | Gussi Films | false | false |
| 28 | 15 | Swing Vote | $23,712 | -73.5% | 57 | -40 | $416 | $153,070 | 2 | Quality Films | false | false |
| 29 | 21 | Mirrors | $23,389 | -54.7% | 32 | -62 | $730 | $3,605,795 | 7 | 20th Century Fox International | false | false |
| 30 | 25 | Be Kind Rewind | $22,319 | -43.3% | 38 | -31 | $587 | $171,963 | 3 | Videocine | false | false |
| 31 | 22 | Kada kien su karma | $18,291 | -63.6% | 62 | -28 | $295 | $317,389 | 6 | Universal Pictures International (UPI) | false | false |
| 32 | 23 | Step Brothers | $17,527 | -63.2% | 36 | -38 | $486 | $606,881 | 8 | Sony Pictures Releasing | false | false |
| 33 | 26 | Fly Me to the Moon 3D | $17,177 | -45.5% | 15 | -2 | $1,145 | $2,075,100 | 37 | Gussi Films | false | false |
| 34 | 27 | Spam | $16,780 | -41% | 22 | -50 | $762 | $471,795 | 4 | Corazón Films | false | false |
| 35 | - | Unrest | $16,501 | - | 18 | - | $916 | $912,300 | 34 | - | false | false |
| 36 | 39 | The Killing Gene | $13,417 | +14.5% | 29 | -17 | $462 | $108,054 | 3 | Quality Films | false | false |
| 37 | - | An American Crime | $12,439 | - | 14 | - | $888 | $552,632 | 15 | Quality Films | false | false |
| 38 | - | The Unknown Woman | $11,041 | - | 11 | - | $1,003 | $44,322 | 2 | Quality Films | false | false |
| 39 | - | My Brother 2008 Re-release | $8,420 | - | 17 | - | $495 | $48,235 | 2 | N/A | false | false |
| 40 | - | The Other Boleyn Girl | $7,899 | - | 10 | - | $789 | $1,565,789 | 15 | Gussi Films | false | false |
| 41 | - | The Ugly Duckling and Me! | $7,804 | - | 23 | - | $339 | $376,765 | 12 | Quality Films | false | false |
| 42 | 32 | The Condemned | $7,192 | -65.8% | 19 | -17 | $378 | $167,878 | 6 | Corazón Films | false | false |
| 43 | 41 | Funny Games | $6,705 | -30.2% | 20 | -6 | $335 | $187,860 | 8 | Universal Pictures International (UPI) | false | false |
| 44 | - | The Host | $6,174 | - | 13 | - | $474 | $136,110 | 11 | Gussi Films | false | false |
| 45 | 33 | Tear This Heart Out | $6,158 | -62.2% | 10 | -14 | $615 | $9,026,130 | 10 | 20th Century Fox International | false | false |
| 46 | - | Hunting and Gathering | $5,649 | - | 10 | - | $564 | $43,136 | 3 | Cinemas Nueva Era | false | false |
| 47 | 43 | Frozen River | $5,177 | -31.6% | 6 | -1 | $862 | $18,245 | 2 | Sony Pictures Releasing | false | false |
| 48 | 36 | Teo's Journey | $4,979 | -66.4% | 39 | -35 | $127 | $149,095 | 6 | Videocine | false | false |
| 49 | 34 | Dedication 2008 Re-release | $4,604 | -71% | 11 | -21 | $418 | $128,699 | 6 | Quality Films | false | false |
| 50 | 28 | Bangkok Dangerous | $4,577 | -83.2% | 14 | -29 | $326 | $1,776,022 | 8 | Gussi Films | false | false |
| 51 | - | Charlie Bartlett | $4,289 | - | 14 | - | $306 | $123,264 | 7 | Azteca Films | false | false |
| 52 | - | The Forbidden Kingdom | $4,225 | - | 10 | - | $422 | $1,914,300 | 10 | Zima Entertainment | false | false |
| 53 | 38 | Satanás | $4,025 | -70.8% | 8 | -29 | $503 | $86,331 | 3 | Gussi Films | false | false |
| 54 | - | A Soap 2008 Re-release | $3,795 | - | 6 | - | $632 | $23,681 | 5 | Alphaville | false | false |
| 55 | - | 40 días | $2,910 | - | 15 | - | $194 | $22,514 | 7 | Gussi Films | false | false |
| 56 | 31 | Divina confusión | $2,897 | -88.4% | 24 | -91 | $120 | $887,620 | 8 | Videocine | false | false |
| 57 | - | Pamela por amor | $2,736 | - | 5 | - | $547 | $74,392 | 11 | N/A | false | false |
| 58 | - | 24 Frames of Terror | $2,656 | - | 6 | - | $442 | $35,722 | 1 | N/A | true | false |
| 59 | - | Bajo Juárez: La ciudad devorando a sus hijas | $2,625 | - | 7 | - | $375 | $74,778 | 7 | N/A | false | false |
| 60 | - | Sex and Death 101 | $2,565 | - | 7 | - | $366 | $199,056 | 13 | Quality Films | false | false |
| 61 | 40 | Pineapple Express | $2,239 | -80.4% | 15 | -18 | $149 | $103,503 | 6 | Sony Pictures Releasing | false | false |
| 62 | - | Valentina: The Movie | $2,216 | - | 9 | - | $246 | $197,818 | 1 | N/A | true | false |
| 63 | 49 | Espérame en otro mundo | $2,056 | +14,585.7% | 16 | +12 | $128 | $24,080 | 4 | Videocine | false | false |
| 64 | - | It's Better If Gabriela Doesn't Die | $1,903 | - | 22 | - | $86 | $60,420 | 9 | Corazón Films | false | false |
| 65 | - | Private Fears in Public Places | $1,799 | - | 8 | - | $224 | $198,990 | 21 | Alphaville | false | false |
| 66 | - | Anna M. | $1,661 | - | 3 | - | $553 | $39,854 | 10 | Alphaville | false | false |
| 67 | 46 | Caramel | $1,640 | -40.4% | 6 | -2 | $273 | $79,812 | 8 | Zima Entertainment | false | false |
| 68 | - | Las vidas de Celia | $1,591 | - | 9 | - | $176 | $32,826 | 29 | Alphaville | false | false |
| 69 | - | Mad Money | $1,498 | - | 6 | - | $249 | $827,890 | 14 | Corazón Films | false | false |
| 70 | - | Red Like the Sky 2008 Re-release | $1,378 | - | 5 | - | $275 | $126,293 | 14 | Quality Films | false | false |
| 71 | 35 | Eagle Eye | $1,367 | -91.2% | 7 | -15 | $195 | $2,575,644 | 8 | Paramount Pictures International | false | false |
| 72 | 42 | Tinker Bell | $1,361 | -84.2% | 11 | -37 | $123 | $3,143,566 | 9 | Walt Disney Pictures | false | false |
| 73 | - | Nesio | $1,189 | - | 5 | - | $237 | $10,696 | 4 | Film House | false | false |
| 74 | - | Babylon A.D. | $1,179 | - | 2 | - | $589 | $3,375,100 | 11 | 20th Century Fox International | false | false |
| 75 | - | Sea Monsters: A Prehistoric Adventure | $1,176 | - | 1 | - | $1,176 | $24,118 | 8 | National Geographic Cinema Ventures | false | false |
| 76 | - | Hasta la muerte | $1,167 | - | 5 | - | $233 | $177,209 | 27 | Azteca Films | false | false |
| 77 | - | La sangre iluminada | $1,123 | - | 7 | - | $160 | $18,937 | 30 | MV Films | false | false |
| 78 | - | U2 3D | $1,110 | - | 2 | - | $555 | $467,071 | 12 | National Geographic Cinema Ventures | false | false |
| 79 | - | Ira & Abby | $1,045 | - | 7 | - | $149 | $242,103 | 28 | Corazón Films | false | false |
| 80 | - | Harold & Kumar Escape from Guantanamo Bay | $1,015 | - | 10 | - | $101 | $173,353 | 13 | Gussi Films | false | false |
| 81 | - | Molière | $1,007 | - | 6 | - | $167 | $139,212 | 11 | Universal Pictures International (UPI) | false | false |
| 82 | - | The Diving Bell and the Butterfly | $1,001 | - | 2 | - | $500 | $349,103 | 22 | Gussi Films | false | false |
| 83 | - | Todos los días son tuyos | $997 | - | 10 | - | $99 | $115,635 | 12 | Corazón Films | false | false |
| 84 | - | Tideland | $928 | - | 1 | - | $928 | $15,507 | 6 | N/A | false | false |
| 85 | - | Semi-Pro | $835 | - | 8 | - | $104 | $44,872 | 10 | Gussi Films | false | false |
| 86 | - | College Road Trip | $828 | - | 1 | - | $828 | $2,859,785 | 15 | Walt Disney Pictures | false | false |
| 87 | - | La capture | $798 | - | 3 | - | $266 | $35,154 | 5 | N/A | false | false |
| 88 | - | Tell No One | $792 | - | 1 | - | $792 | $85,442 | 32 | Cinemas Nueva Era | false | false |
| 89 | - | The Bubble | $729 | - | 3 | - | $243 | $72,566 | 16 | Alphaville | false | false |
| 90 | - | Mezcal | $713 | - | 5 | - | $142 | $32,394 | 75 | Instituto Mexicano de Cinematografía (IMCINE) | false | false |
| 91 | 29 | Balls of Fury | $706 | -97.3% | 9 | -41 | $78 | $40,911 | 2 | Gussi Films | false | false |
| 92 | - | Sleuth | $689 | - | 2 | - | $344 | $200,561 | 43 | Sony Pictures Releasing | false | false |
| 93 | 37 | Forgetting Sarah Marshall | $616 | -95.8% | 8 | -32 | $77 | $784,928 | 9 | Universal Pictures International (UPI) | false | false |
| 94 | - | Never Back Down | $533 | - | 3 | - | $177 | $326,117 | 13 | Corazón Films | false | false |
| 95 | - | Death of a President | $490 | - | 2 | - | $245 | $66,373 | 20 | Quality Films | false | false |
| 96 | - | Familia tortuga | $421 | - | 1 | - | $421 | $7,660 | 3 | Canana Films | false | false |
| 97 | - | Irina Palm | $407 | - | 3 | - | $135 | $254,556 | 25 | Zima Entertainment | false | false |
| 98 | - | Mamma Mia! | $371 | - | 1 | - | $371 | $3,133,271 | 10 | Universal Pictures International (UPI) | false | false |
| 99 | - | P2 | $346 | - | 1 | - | $346 | $731,855 | 49 | Zima Entertainment | false | false |
| 100 | - | Martian Child | $321 | - | 1 | - | $321 | $423,801 | 32 | Gussi Films | false | false |
| 101 | - | High School Musical: El Desafío | $309 | - | 1 | - | $309 | $4,262,178 | 11 | Walt Disney Pictures | false | false |
| 102 | - | You, the Living | $295 | - | 1 | - | $295 | $12,066 | 8 | MAC Releasing | false | false |
| 103 | - | Eros una vez María | $294 | - | 2 | - | $147 | $289,443 | 54 | MV Films | false | false |
| 104 | - | Cocalero 2008 Re-release | $279 | - | 1 | - | $279 | $15,266 | 11 | N/A | false | false |
| 105 | - | The Sugar Curtain | $276 | - | 1 | - | $276 | $6,509 | 6 | N/A | false | false |
| 106 | - | See No Evil | $274 | - | 1 | - | $274 | $212,055 | 26 | Gussi Films | false | false |
| 107 | - | Persepolis | $254 | - | 3 | - | $84 | $159,970 | 24 | Film House | false | false |
| 108 | 45 | Los campeones de la lucha libre | $247 | -91.1% | 3 | -26 | $82 | $406,398 | 5 | - | false | false |
| 109 | - | Death Proof | $218 | - | 2 | - | $109 | $85,212 | 26 | Zima Entertainment | false | false |
| 110 | - | Under the Same Moon | $187 | - | 1 | - | $187 | $9,577,733 | 35 | 20th Century Fox International | false | false |
| 111 | - | Cumbia callera | $181 | - | 2 | - | $90 | $27,594 | 13 | Instituto Mexicano de Cinematografía (IMCINE) | false | false |
| 112 | - | The Wedding Weekend | $136 | - | 2 | - | $68 | $4,287 | 30 | Zima Entertainment | false | false |
| 113 | - | The Bucket List | $128 | - | 1 | - | $128 | $6,582,890 | 43 | Warner Bros. | false | false |
| 114 | - | So Ambitious 2008 Re-release | $127 | - | 1 | - | $127 | $68,089 | 17 | Cinemas Nueva Era | false | false |
| 115 | - | Dan in Real Life | $95 | - | 2 | - | $47 | $505,556 | 11 | Videocine | false | false |
| 116 | - | Flawless | $76 | - | 2 | - | $38 | $1,000,041 | 21 | Gussi Films | false | false |
| 117 | - | Into the Wild | $73 | - | 1 | - | $73 | $180,215 | 32 | Paramount Pictures International | false | false |
| 118 | - | El brindis | $71 | - | 1 | - | $71 | $133,431 | 30 | David Distribucion | false | false |
| 119 | - | Factory Girl | $35 | - | 1 | - | $35 | $122,137 | 29 | Film House | false | false |
| 120 | - | La frontera infinita | $18 | - | 1 | - | $18 | $1,849 | 4 | Instituto Mexicano de Cinematografía (IMCINE) | false | false |
