| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Suspect X | $2,978,823 | -39.5% | 410 | - | $7,265 | $23,083,515 | 3 | Toho | false | false |
| 2 | - | Eagle Eye | $2,363,464 | - | 306 | - | $7,723 | $2,363,464 | 1 | Herald Film Company | true | false |
| 3 | - | P.S. I Love You | $1,392,611 | - | 276 | - | $5,045 | $1,392,611 | 1 | Toho-Towa | true | false |
| 4 | 4 | Departures | $676,272 | -31.3% | 221 | +1 | $3,060 | $21,420,951 | 6 | Shochiku | false | false |
| 5 | 5 | Farewell Kamen Rider Den-O: Final Countdown | $618,680 | -36.9% | 156 | - | $3,965 | $4,702,035 | 3 | Toei Company | false | false |
| 6 | 3 | Paco and the Magical Book | $592,067 | -40% | 292 | - | $2,027 | $19,682,955 | 6 | Toho | false | false |
| 7 | 2 | Wanted | $449,607 | -55.4% | 349 | -37 | $1,288 | $22,049,616 | 5 | Toho-Towa | false | false |
| 8 | 9 | Ponyo | $394,704 | -38.6% | 481 | - | $820 | $141,808,040 | 14 | Toho | false | false |
| 9 | 8 | Ikigami | $387,256 | -44.4% | 252 | - | $1,536 | $6,371,176 | 4 | Toho | false | false |
| 10 | 7 | 20th Century Boys 1: Beginning of the End | $353,969 | -49.3% | 300 | - | $1,179 | $35,342,872 | 8 | Toho | false | false |
| 11 | 6 | Iron Man | $343,453 | -56.7% | 363 | -17 | $946 | $7,774,120 | 4 | Sony Pictures Releasing | false | false |
| 12 | 10 | Get Smart | $184,376 | -66.3% | 205 | - | $899 | $1,347,482 | 2 | Warner Bros. | false | false |
| 13 | 12 | Superior 8 Ultra Brothers | $124,591 | -54.4% | 148 | -31 | $841 | $7,590,696 | 6 | Shochiku | false | false |
| 14 | 13 | Nights in Rodanthe | $118,253 | -55.1% | 255 | -4 | $463 | $3,786,028 | 4 | Warner Bros. | false | false |
| 15 | - | Resident Evil: Degeneration | $97,237 | - | 3 | - | $32,412 | $97,237 | 1 | Sony Pictures Releasing | true | false |
| 16 | 11 | Hancock | $22,774 | -91.9% | 162 | -188 | $140 | $28,343,649 | 8 | Sony Pictures Releasing | false | false |
| 17 | 16 | Before the Devil Knows You're Dead | $18,007 | -6.6% | 2 | +1 | $9,003 | $63,496 | 2 | Sony Pictures Releasing | false | false |
| 18 | 17 | Zombie Strippers! | $8,285 | -39.8% | 7 | - | $1,183 | $40,125 | 2 | Sony Pictures Releasing | false | false |
| 19 | 18 | Pistol Whipped | $1,371 | +329.8% | 1 | -1 | $1,371 | $77,443 | 6 | Sony Pictures Releasing | false | false |
