| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Beverly Hills Chihuahua | $409,563 | - | 54 | - | $7,584 | $598,078 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Nights in Rodanthe | $200,743 | -14.2% | 42 | - | $4,779 | $549,701 | 2 | Warner Bros. | false | false |
| 3 | 2 | A Boyfriend for My Wife | $152,548 | -15.4% | 85 | +7 | $1,794 | $5,477,781 | 9 | Walt Disney Pictures | false | false |
| 4 | 3 | Mirrors | $139,984 | -3.8% | 35 | +4 | $3,999 | $373,102 | 2 | 20th Century Fox International | false | false |
| 5 | - | Appaloosa | $131,126 | - | 30 | - | $4,370 | $170,595 | 1 | Distribution Company | true | false |
| 6 | - | Hellboy II: The Golden Army | $120,825 | - | 40 | - | $3,020 | $161,631 | 1 | United International Pictures | true | false |
| 7 | 5 | You Don't Mess with the Zohan | $75,996 | -3.2% | 30 | - | $2,533 | $553,462 | 4 | Sony Pictures Releasing | false | false |
| 8 | 7 | In Bruges | $66,782 | -13.7% | 19 | - | $3,514 | $184,116 | 2 | Distribution Company | false | false |
| 9 | 6 | Tropic Thunder | $64,742 | -17.3% | 48 | +1 | $1,348 | $1,236,107 | 6 | United International Pictures | false | false |
| 10 | 8 | Taken | $58,940 | +2.8% | 30 | - | $1,964 | $405,888 | 4 | 20th Century Fox International | false | false |
| 11 | 9 | Mamma Mia! | $45,290 | -14.1% | 50 | +10 | $905 | $1,464,473 | 8 | United International Pictures | false | false |
| 12 | 4 | Tinker Bell | $43,562 | -45.3% | 55 | - | $792 | $780,321 | 5 | Walt Disney Pictures | false | false |
| 13 | 13 | My Brother is an Only Child | $27,309 | -4.5% | 13 | +1 | $2,100 | $204,099 | 4 | Alfa Films | false | false |
| 14 | 11 | Dan in Real Life | $25,506 | -33.6% | 32 | +1 | $797 | $184,842 | 3 | Distribution Company | false | false |
| 15 | 10 | The Forbidden Kingdom | $18,863 | -63.4% | 36 | -4 | $523 | $93,277 | 2 | - | false | false |
| 16 | 16 | Manual of Love 2008 Re-release | $17,880 | -5.6% | 9 | - | $1,986 | $85,902 | 3 | Notro Films | false | false |
| 17 | 14 | The Strangers | $15,337 | -43.9% | 31 | - | $494 | $334,638 | 5 | Distribution Company | false | false |
| 18 | 15 | REC | $13,886 | -32.4% | 14 | -3 | $991 | $216,709 | 5 | CDI Films | false | false |
| 19 | 12 | Eagle Eye | $12,993 | -63.7% | 33 | -7 | $393 | $168,025 | 3 | United International Pictures | false | false |
| 20 | 17 | Reasons for Not Falling in Love | $10,399 | -44.6% | 44 | +1 | $236 | $561,523 | 6 | Distribution Company | false | false |
| 21 | 19 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $8,502 | -22.6% | 2 | - | $4,251 | $147,893 | 6 | Walt Disney Pictures | false | false |
| 22 | 18 | Superhero Movie | $7,778 | -53.2% | 33 | +2 | $235 | $321,278 | 5 | Pachamama Cine | false | false |
| 23 | 21 | La próxima estación | $7,534 | -9.7% | 13 | +12 | $579 | $115,342 | 6 | Primer Plano Film Group | false | false |
| 24 | 27 | Journey to the Center of the Earth | $4,951 | +66.5% | 9 | - | $550 | $901,866 | 13 | Distribution Company | false | false |
| 25 | 24 | Francesca | $4,808 | -11.9% | 3 | -3 | $1,602 | $177,718 | 13 | IFA | false | false |
| 26 | 23 | Irina Palm | $2,731 | -58.4% | 5 | -6 | $546 | $39,304 | 3 | Alfa Films | false | false |
| 27 | - | The Princess of Nebraska | $2,653 | - | 3 | - | $884 | $3,456 | 1 | Primer Plano Film Group | true | false |
| 28 | 22 | Wanted | $2,459 | -67.9% | 19 | -17 | $129 | $554,104 | 7 | United International Pictures | false | false |
| 29 | 34 | The Headless Woman | $2,197 | +55.8% | 6 | +1 | $366 | $136,650 | 8 | Distribution Company | false | false |
| 30 | 20 | Babylon A.D. | $2,138 | -75.5% | 15 | -13 | $142 | $213,273 | 6 | 20th Century Fox International | false | false |
| 31 | 26 | Four Minutes | $1,835 | -44.7% | 3 | -6 | $611 | $164,058 | 7 | Alfa Films | false | false |
| 32 | 35 | Impunidad | $1,718 | +28.6% | 4 | - | $429 | $3,539 | 2 | Primer Plano Film Group | false | false |
| 33 | 28 | L'invité | $1,633 | -44.1% | 4 | -2 | $408 | $133,458 | 7 | Pachamama Cine | false | false |
| 34 | 32 | Nim's Island | $1,523 | -3.3% | 15 | +5 | $101 | $156,800 | 10 | United International Pictures | false | false |
| 35 | 25 | Lo que sé de Lola | $1,275 | -63% | 2 | -1 | $637 | $6,291 | 2 | 791 Cine | false | false |
| 36 | 30 | Black Sheep | $1,069 | -40.4% | 4 | -5 | $267 | $148,343 | 8 | Pachamama Cine | false | false |
| 37 | 36 | The Bottle | $999 | -23.4% | 6 | +1 | $166 | $85,222 | 5 | Primer Plano Film Group | false | false |
| 38 | 31 | Meet Dave | $998 | -37.2% | 8 | - | $124 | $286,032 | 10 | 20th Century Fox International | false | false |
| 39 | 45 | WALL·E | $839 | +14% | 7 | -1 | $119 | $4,661,010 | 14 | Walt Disney Pictures | false | false |
| 40 | 43 | 100% lucha, la película | $692 | -15% | 7 | -1 | $98 | $920,044 | 14 | Primer Plano Film Group | false | false |
| 41 | 46 | Valentina: The Movie | $690 | +21.1% | 5 | - | $138 | $367,053 | 14 | Pachamama Cine | false | false |
| 42 | 53 | Abrígate | $678 | +132.2% | 1 | - | $678 | $2,973 | 5 | Walt Disney Pictures | false | false |
| 43 | 47 | Death at a Funeral | $556 | +10.5% | 2 | - | $278 | $2,152,864 | 32 | - | false | false |
| 44 | 62 | Los superagentes, nueva generación | $508 | +361.8% | 8 | +4 | $63 | $864,447 | 13 | Argentina Sono Film S.A.C.I. | false | false |
| 45 | 48 | The Diving Bell and the Butterfly | $488 | - | 2 | - | $244 | $103,323 | 9 | Alfa Films | false | false |
| 46 | 39 | Aaltra | $476 | -55.7% | 1 | -1 | $476 | $5,856 | 3 | Vera Films | false | false |
| 47 | - | U2 3D | $456 | - | 1 | - | $456 | $150,795 | 29 | IMAX | false | false |
| 48 | 59 | The Dark Knight | $448 | +187.2% | 3 | - | $149 | $5,480,788 | 13 | Warner Bros. | false | false |
| 49 | 41 | Chaos | $403 | -56.9% | 1 | -3 | $403 | $93,387 | 9 | - | false | false |
| 50 | 58 | Paranoid Park | $383 | +110.4% | 1 | - | $383 | $9,749 | 8 | Alfa Films | false | false |
| 51 | 38 | Star Wars: The Clone Wars | $363 | -66.8% | 5 | -2 | $72 | $236,200 | 9 | Warner Bros. | false | false |
| 52 | - | The Oxford Murders | $361 | - | 1 | - | $361 | $589,788 | 23 | Pachamama Cine | false | false |
| 53 | 29 | Run Fatboy Run | $360 | -83.4% | 3 | -3 | $120 | $79,737 | 7 | Distribution Company | false | false |
| 54 | 61 | A Girl Cut in Two | $354 | +176.6% | 1 | - | $354 | $285,500 | 12 | Alfa Films | false | false |
| 55 | 49 | Kung Fu Panda | $353 | -16.4% | 4 | +2 | $88 | $5,606,701 | 15 | United International Pictures | false | false |
| 56 | - | Enchanted | $261 | - | 1 | - | $261 | $2,862,455 | 41 | Walt Disney Pictures | false | false |
| 57 | - | Awake | $210 | - | 1 | - | $210 | $274,878 | 22 | Distribution Company | false | false |
| 58 | - | Lamb of God | $196 | - | 1 | - | $196 | $146,898 | 23 | Alfa Films | false | false |
| 59 | - | The Orphanage | $187 | - | 1 | - | $187 | $752,000 | 31 | CDI Films | false | false |
| 60 | 57 | Viva High School Musical | $166 | -32% | 2 | - | $83 | $1,766,642 | 13 | Walt Disney Pictures | false | false |
| 61 | 68 | Cassandra's Dream | $156 | +372.7% | 1 | - | $156 | $583,007 | 19 | Alfa Films | false | false |
| 62 | 66 | Conversations with My Gardener | $150 | +177.8% | 1 | - | $150 | $238,643 | 25 | Alfa Films | false | false |
| 63 | - | The Game Plan | $111 | - | 1 | - | $111 | $1,519,005 | 35 | Walt Disney Pictures | false | false |
| 64 | - | Sex and the City | $109 | - | 1 | - | $109 | $1,574,423 | 18 | Distribution Company | false | false |
| 65 | 40 | The X Files: I Want to Believe | $69 | -92.7% | 5 | -5 | $13 | $681,509 | 9 | 20th Century Fox International | false | false |
| 66 | 64 | Hunting and Gathering | $67 | -24.7% | 1 | - | $67 | $21,258 | 7 | Notro Films | false | false |
| 67 | 63 | The Chronicles of Narnia: Prince Caspian | $65 | -40.9% | 2 | - | $32 | $3,701,996 | 18 | Walt Disney Pictures | false | false |
| 68 | - | Shine a Light | $54 | - | 1 | - | $54 | $99,576 | 27 | Distribution Company | false | false |
| 69 | - | Pellet | $47 | - | 1 | - | $47 | $30,903 | 360 | Primer Plano Film Group | false | false |
| 70 | 55 | Get Smart | $31 | -89% | 1 | -3 | $31 | $2,251,760 | 16 | Warner Bros. | false | false |
| 71 | 65 | The Nest | $21 | -75.6% | 1 | - | $21 | $1,008,755 | 25 | Distribution Company | false | false |
| 72 | - | Amélie | $17 | - | 2 | - | $8 | $587,337 | 351 | Buena Vista International | false | false |
