| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Boy in the Striped Pajamas | $2,374,965 | -26.9% | 260 | - | $9,134 | $6,320,485 | 2 | Walt Disney Pictures | false | false |
| 2 | - | Righteous Kill | $1,646,052 | - | 315 | - | $5,225 | $1,646,052 | 1 | Sony Pictures Releasing | true | false |
| 3 | - | Mirrors | $1,638,855 | - | 298 | - | $5,499 | $1,638,855 | 1 | 20th Century Fox International | true | false |
| 4 | - | Death Race | $1,200,828 | - | 250 | - | $4,803 | $1,200,828 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | 2 | Vicky Cristina Barcelona | $1,069,352 | -47% | 334 | - | $3,201 | $7,964,691 | 3 | Warner Bros. | false | false |
| 6 | 4 | Tropic Thunder | $656,703 | -51.1% | 302 | -21 | $2,174 | $2,245,888 | 2 | Paramount Pictures International | false | false |
| 7 | 3 | Babylon A.D. | $560,933 | -63.4% | 301 | -3 | $1,863 | $2,469,417 | 2 | Aurum Films | false | false |
| 8 | - | Sangre de mayo | $389,746 | - | 243 | - | $1,603 | $390,549 | 1 | Alta Films | true | false |
| 9 | 7 | Meet Dave | $383,394 | -45.5% | 231 | -24 | $1,659 | $2,243,515 | 3 | 20th Century Fox International | false | false |
| 10 | 6 | Journey to the Center of the Earth | $378,292 | -50.9% | 191 | -70 | $1,980 | $7,920,638 | 5 | TriPictures | false | false |
| 11 | 10 | Mamma Mia! | $336,776 | -37% | 164 | -64 | $2,053 | $17,897,849 | 8 | Universal Pictures International (UPI) | false | false |
| 12 | 11 | The Blind Sunflowers | $321,194 | -37.3% | 176 | -9 | $1,824 | $4,878,540 | 6 | Alta Films | false | false |
| 13 | 9 | Che: Part One | $294,571 | -54.9% | 224 | -105 | $1,315 | $9,061,149 | 5 | 20th Century Fox International | false | false |
| 14 | 5 | The Strangers | $270,070 | -69.2% | 203 | -29 | $1,330 | $3,073,708 | 3 | Universal Pictures International (UPI) | false | false |
| 15 | 8 | Wanted | $172,011 | -73.7% | 184 | -159 | $934 | $6,926,453 | 4 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Nim's Island | $153,321 | -42.9% | 131 | -70 | $1,170 | $3,538,566 | 5 | Universal Pictures International (UPI) | false | false |
| 17 | - | U2 3D | $126,426 | - | 21 | - | $6,020 | $126,426 | 1 | Precision Films | true | false |
| 18 | - | No me pidas que te bese porque te besaré | $126,143 | - | 99 | - | $1,274 | $126,143 | 1 | On Pictures | true | false |
| 19 | 16 | Spirit of the Forest | $95,068 | -35.5% | 99 | -42 | $960 | $902,044 | 4 | Manga Entertainment | false | false |
| 20 | 12 | Passengers | $87,867 | -73% | 140 | -9 | $627 | $477,748 | 2 | DeAPlaneta | false | false |
| 21 | 14 | My Prison Yard | $81,405 | -57.3% | 92 | +1 | $884 | $330,051 | 2 | Warner Bros. | false | false |
| 22 | - | Lemon Tree | $64,542 | - | 22 | - | $2,933 | $64,542 | 1 | Golem Distribución | true | false |
| 23 | 15 | The Conspiracy | $58,813 | -63.5% | 46 | -70 | $1,278 | $2,616,313 | 5 | Sony Pictures Releasing | false | false |
| 24 | 17 | WALL·E | $54,890 | -45.7% | 76 | -37 | $722 | $14,783,948 | 9 | Walt Disney Pictures | false | false |
| 25 | 19 | The Grocer's Son | $46,737 | -37.2% | 26 | -1 | $1,797 | $450,160 | 4 | Karma Films | false | false |
| 26 | - | Married Life | $45,095 | - | 19 | - | $2,373 | $45,095 | 1 | Versus Entertainment | true | false |
| 27 | 26 | I've Loved You So Long | $23,658 | -36.7% | 17 | -12 | $1,391 | $566,954 | 6 | Golem Distribución | false | false |
| 28 | 18 | The Air I Breathe | $22,570 | -77.2% | 25 | -34 | $902 | $409,218 | 3 | Filmax | false | false |
| 29 | 24 | The Unknown Woman | $21,058 | -58.1% | 28 | -6 | $752 | $90,425 | 2 | Festival Films S.L. | false | false |
| 30 | - | Battle in Seattle | $19,824 | - | 41 | - | $483 | $19,824 | 1 | Filmax | true | false |
| 31 | - | Bullet in the Head | $18,507 | - | 18 | - | $1,028 | $18,507 | 1 | Wanda Visión S.A. | true | false |
| 32 | 20 | The Dark Knight | $18,409 | -73.6% | 27 | -39 | $681 | $16,273,010 | 8 | Warner Bros. | false | false |
| 33 | 21 | 3:10 to Yuma | $17,305 | -74.4% | 21 | -49 | $824 | $1,565,144 | 5 | Filmax | false | false |
| 34 | 28 | Space Chimps | $15,083 | -35.7% | 20 | -13 | $754 | $1,756,986 | 7 | Aurum Films | false | false |
| 35 | 22 | You Don't Mess with the Zohan | $13,170 | -80.4% | 26 | -63 | $506 | $9,909,885 | 7 | Sony Pictures Releasing | false | false |
| 36 | 27 | Carlitos and the Chance of a Lifetime | $12,884 | -60.2% | 35 | -34 | $368 | $1,926,001 | 7 | 20th Century Fox International | false | false |
| 37 | 23 | Hellboy II: The Golden Army | $10,864 | -79.7% | 14 | -58 | $776 | $6,411,384 | 6 | Universal Pictures International (UPI) | false | false |
| 38 | 25 | Step Up 2: The Streets | $10,546 | -77.9% | 24 | -41 | $439 | $3,215,870 | 7 | Walt Disney Pictures | false | false |
| 39 | 33 | One Hundred Nails 2008 Re-release | $9,259 | -31.7% | 3 | -2 | $3,086 | $60,432 | 4 | Sagrera TV | false | false |
| 40 | 30 | Star Wars: The Clone Wars | $8,883 | -51.7% | 28 | -12 | $317 | $1,655,558 | 6 | Warner Bros. | false | false |
| 41 | 31 | One Word from You | $7,096 | -58.9% | 7 | -12 | $1,013 | $1,521,744 | 7 | Alta Films | false | false |
| 42 | - | Kung Fu Panda | $5,538 | - | 12 | - | $461 | $19,371,998 | 13 | Universal Pictures International (UPI) | false | false |
| 43 | - | Travelers and Magicians 2008 Re-release | $5,245 | - | 2 | - | $2,622 | $16,141 | 2 | - | false | false |
| 44 | 32 | The Merry Widow | $4,977 | -66.9% | 7 | -6 | $711 | $695,454 | 7 | Notro Films | false | false |
| 45 | 34 | Saint-Jacques... La Mecque 2007 Re-release | $4,177 | -63% | 6 | -10 | $696 | $470,889 | 9 | Baditri | false | false |
| 46 | 40 | Rivers and Tides 2008 Re-release | $2,918 | +0.3% | 2 | +1 | $1,459 | $56,879 | 7 | Karma Films | false | false |
| 47 | 35 | Goodbye Beautiful Days | $2,688 | -63.4% | 3 | -9 | $896 | $637,978 | 10 | Golem Distribución | false | false |
| 48 | 39 | CSNY/Déjà Vu | $1,457 | -62.9% | 2 | - | $728 | $6,727 | 2 | Avalon | false | false |
| 49 | 46 | I Served the King of England | $1,198 | -15.9% | 4 | -4 | $299 | $621,209 | 12 | Wanda Visión S.A. | false | false |
| 50 | 36 | Before the Devil Knows You're Dead | $1,112 | -83% | 3 | -7 | $370 | $3,614,030 | 20 | Baditri | false | false |
| 51 | - | The Mummy: Tomb of the Dragon Emperor | $958 | - | 3 | - | $319 | $18,965,712 | 10 | Universal Pictures International (UPI) | false | false |
| 52 | 38 | King of the Hill | $877 | -79.6% | 12 | -15 | $73 | $282,430 | 4 | Walt Disney Pictures | false | false |
| 53 | - | Into the Wild | $552 | - | 2 | - | $276 | $777,100 | 37 | Universal Pictures International (UPI) | false | false |
| 54 | 43 | Sex and the City | $377 | -76.3% | 3 | -3 | $125 | $8,718,365 | 16 | TriPictures | false | false |
| 55 | 41 | Made of Honor | $373 | -86.1% | 1 | -3 | $373 | $6,337,777 | 19 | Sony Pictures Releasing | false | false |
| 56 | 44 | P.S. I Love You | $359 | -76% | 1 | -1 | $359 | $3,853,788 | 13 | Filmax | false | false |
| 57 | 52 | How to Cook Your Life | $342 | -46.3% | 1 | -1 | $342 | $74,029 | 14 | Karma Films | false | false |
| 58 | 51 | Lovewrecked | $325 | -56% | 2 | -3 | $162 | $123,967 | 4 | Flins & Piniculas | false | false |
| 59 | - | In Bruges | $312 | - | 3 | - | $104 | $1,102,022 | 12 | Universal Pictures International (UPI) | false | false |
| 60 | 50 | Quiet Chaos | $303 | -67.5% | 1 | -1 | $303 | $528,438 | 16 | Alta Films | false | false |
| 61 | 48 | Late Bloomers | $234 | -81.4% | 1 | - | $234 | $415,748 | 22 | - | false | false |
| 62 | 57 | 21 | $209 | -34.7% | 1 | -1 | $209 | $6,784,397 | 26 | Sony Pictures Releasing | false | false |
| 63 | 45 | The Mist | $188 | -87.1% | 1 | -1 | $188 | $3,500,163 | 19 | Notro Films | false | false |
| 64 | 42 | Promise Me This | $165 | -92.5% | 1 | -1 | $165 | $342,203 | 13 | Baditri | false | false |
| 65 | 53 | Hancock | $140 | -74.1% | 1 | -3 | $140 | $26,259,302 | 12 | Sony Pictures Releasing | false | false |
| 66 | - | Untraceable | $83 | - | 1 | - | $83 | $1,893,655 | 27 | Universal Pictures International (UPI) | false | false |
| 67 | 37 | Bangkok Dangerous | $71 | -98.9% | 1 | -8 | $71 | $3,492,207 | 7 | DeAPlaneta | false | false |
| 68 | 58 | Iron Man | $29 | -90.8% | 1 | -2 | $29 | $11,785,849 | 23 | Sony Pictures Releasing | false | false |
