| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Nights in Rodanthe | $233,970 | - | 42 | - | $5,570 | $233,970 | 1 | Warner Bros. | true | false |
| 2 | 1 | A Boyfriend for My Wife | $180,331 | -38% | 78 | +2 | $2,311 | $5,227,047 | 8 | Walt Disney Pictures | false | false |
| 3 | - | Mirrors | $145,441 | - | 31 | - | $4,691 | $145,441 | 1 | 20th Century Fox International | true | false |
| 4 | 4 | Tinker Bell | $79,571 | -26.4% | 55 | -3 | $1,446 | $685,014 | 4 | Walt Disney Pictures | false | false |
| 5 | 2 | You Don't Mess with the Zohan | $78,539 | -36.8% | 30 | - | $2,617 | $461,007 | 3 | Sony Pictures Releasing | false | false |
| 6 | 3 | Tropic Thunder | $78,282 | -32.3% | 47 | -1 | $1,665 | $1,129,186 | 5 | United International Pictures | false | false |
| 7 | - | In Bruges | $77,411 | - | 19 | - | $4,074 | $77,411 | 1 | Distribution Company | true | false |
| 8 | 8 | Taken | $57,308 | -29.5% | 30 | - | $1,910 | $307,845 | 3 | 20th Century Fox International | false | false |
| 9 | 5 | Mamma Mia! | $52,726 | -43.3% | 40 | -9 | $1,318 | $1,387,067 | 7 | United International Pictures | false | false |
| 10 | - | The Forbidden Kingdom | $51,561 | - | 40 | - | $1,289 | $51,561 | 1 | - | true | false |
| 11 | 6 | Dan in Real Life | $38,406 | -55% | 31 | - | $1,238 | $141,867 | 2 | Distribution Company | false | false |
| 12 | 7 | Eagle Eye | $35,766 | -56.4% | 40 | - | $894 | $140,739 | 2 | United International Pictures | false | false |
| 13 | 11 | My Brother is an Only Child | $28,608 | -37.8% | 12 | -1 | $2,384 | $162,502 | 3 | Alfa Films | false | false |
| 14 | 9 | The Strangers | $27,362 | -46.8% | 31 | -1 | $882 | $305,650 | 4 | Distribution Company | false | false |
| 15 | 14 | REC | $20,542 | -20.8% | 17 | -3 | $1,208 | $191,212 | 4 | CDI Films | false | false |
| 16 | 13 | Manual of Love 2008 Re-release | $18,932 | -34% | 9 | - | $2,103 | $56,633 | 2 | Notro Films | false | false |
| 17 | 10 | Reasons for Not Falling in Love | $18,756 | -59.5% | 43 | -1 | $436 | $540,094 | 5 | Distribution Company | false | false |
| 18 | 12 | Superhero Movie | $16,628 | -58.7% | 31 | -8 | $536 | $305,532 | 4 | Pachamama Cine | false | false |
| 19 | 19 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $10,982 | -32.6% | 2 | - | $5,491 | $133,885 | 5 | Walt Disney Pictures | false | false |
| 20 | 15 | Babylon A.D. | $8,720 | -58.8% | 28 | -2 | $311 | $208,006 | 5 | 20th Century Fox International | false | false |
| 21 | 18 | La próxima estación | $8,343 | -49.5% | 1 | -11 | $8,343 | $101,454 | 5 | Primer Plano Film Group | false | false |
| 22 | 17 | Wanted | $7,652 | -61% | 36 | -10 | $212 | $547,727 | 6 | United International Pictures | false | false |
| 23 | 16 | Irina Palm | $6,561 | -67.4% | 11 | - | $596 | $33,280 | 2 | Alfa Films | false | false |
| 24 | 21 | Francesca | $5,456 | -34.1% | 6 | - | $909 | $177,507 | 12 | IFA | false | false |
| 25 | - | Lo que sé de Lola | $3,446 | - | 3 | - | $1,148 | $3,446 | 1 | 791 Cine | true | false |
| 26 | 25 | Four Minutes | $3,317 | -34.2% | 9 | - | $368 | $160,495 | 6 | Alfa Films | false | false |
| 27 | 24 | Journey to the Center of the Earth | $2,974 | -43.3% | 9 | -1 | $330 | $927,858 | 12 | Distribution Company | false | false |
| 28 | 22 | L'invité | $2,920 | -62.6% | 6 | -2 | $486 | $130,512 | 6 | Pachamama Cine | false | false |
| 29 | 23 | Run Fatboy Run | $2,164 | -61.7% | 6 | -6 | $360 | $78,538 | 6 | Distribution Company | false | false |
| 30 | 27 | Black Sheep | $1,794 | -54.7% | 9 | -4 | $199 | $146,554 | 7 | Pachamama Cine | false | false |
| 31 | 28 | Meet Dave | $1,589 | -59.4% | 8 | -8 | $198 | $283,575 | 9 | 20th Century Fox International | false | false |
| 32 | 29 | Nim's Island | $1,575 | -57.7% | 10 | -7 | $157 | $153,951 | 9 | United International Pictures | false | false |
| 33 | 39 | The Other Boleyn Girl | $1,555 | -6.2% | 5 | - | $311 | $329,302 | 9 | Distribution Company | false | false |
| 34 | 37 | The Headless Woman | $1,410 | -27.9% | 5 | -2 | $282 | $132,985 | 7 | Distribution Company | false | false |
| 35 | - | Impunidad | $1,336 | - | 4 | - | $334 | $1,336 | 1 | Primer Plano Film Group | true | false |
| 36 | 20 | The Bottle | $1,304 | -90.5% | 5 | -13 | $260 | $83,273 | 4 | Primer Plano Film Group | false | false |
| 37 | - | Los invisibles | $1,149 | - | 1 | - | $1,149 | $1,149 | 1 | Primer Plano Film Group | true | false |
| 38 | 35 | Star Wars: The Clone Wars | $1,092 | -55.6% | 7 | -5 | $156 | $235,347 | 8 | Warner Bros. | false | false |
| 39 | 31 | Aaltra | $1,075 | -63.1% | 2 | - | $537 | $4,969 | 2 | Vera Films | false | false |
| 40 | 26 | The X Files: I Want to Believe | $946 | -77.1% | 10 | -21 | $94 | $681,054 | 8 | 20th Century Fox International | false | false |
| 41 | 30 | Chaos | $934 | -72.3% | 4 | -12 | $233 | $96,041 | 8 | - | false | false |
| 42 | 53 | Café de los maestros | $889 | +149% | 3 | +2 | $296 | $102,594 | 15 | Alfa Films | false | false |
| 43 | 48 | 100% lucha, la película | $814 | +57.8% | 8 | +3 | $101 | $918,974 | 13 | Primer Plano Film Group | false | false |
| 44 | 32 | The Mummy: Tomb of the Dragon Emperor | $769 | -72.3% | 6 | -7 | $128 | $2,790,832 | 10 | United International Pictures | false | false |
| 45 | 40 | WALL·E | $736 | -45.6% | 8 | -4 | $92 | $4,659,950 | 13 | Walt Disney Pictures | false | false |
| 46 | 54 | Valentina: The Movie | $570 | +78.1% | 5 | +2 | $114 | $365,589 | 13 | Pachamama Cine | false | false |
| 47 | - | Death at a Funeral | $503 | - | 2 | - | $251 | $2,151,998 | 31 | Compañía General de la Imagen (CGI) | false | false |
| 48 | 43 | The Diving Bell and the Butterfly | $488 | -57.7% | 2 | -1 | $244 | $102,555 | 8 | Alfa Films | false | false |
| 49 | 55 | Kung Fu Panda | $422 | +41.1% | 2 | -1 | $211 | $5,606,089 | 14 | United International Pictures | false | false |
| 50 | 44 | Lars and the Real Girl | $353 | -47.8% | 2 | -4 | $176 | $74,502 | 7 | Impacto Cine | false | false |
| 51 | - | An American Haunting | $334 | - | 1 | - | $334 | $529,788 | 36 | Distribution Company | false | false |
| 52 | 42 | Golden Door | $322 | -72.1% | 1 | - | $322 | $111,029 | 3 | Primer Plano Film Group | false | false |
| 53 | - | Abrígate | $292 | - | 1 | - | $292 | $2,237 | 4 | Walt Disney Pictures | false | false |
| 54 | 36 | Comedy of Innocence | $291 | -87.9% | 1 | -3 | $291 | $20,717 | 363 | Primer Plano Film Group | false | false |
| 55 | 64 | Get Smart | $283 | +164.5% | 4 | +3 | $70 | $2,251,710 | 15 | Warner Bros. | false | false |
| 56 | 34 | You, the Living | $260 | -89.5% | 1 | -6 | $260 | $20,807 | 5 | Zeta Films | false | false |
| 57 | 65 | High School Musical: El Desafío | $244 | +313.6% | 2 | +1 | $122 | $1,766,399 | 12 | Walt Disney Pictures | false | false |
| 58 | 58 | Paranoid Park | $182 | -32.1% | 1 | -1 | $182 | $282,957 | 7 | Alfa Films | false | false |
| 59 | 33 | The Dark Knight | $156 | -94.3% | 3 | -6 | $52 | $5,479,310 | 12 | Warner Bros. | false | false |
| 60 | - | Bratz | $128 | - | 1 | - | $128 | $44,700 | 34 | Pachamama Cine | false | false |
| 61 | 56 | A Girl Cut in Two | $128 | -55.6% | 1 | -1 | $128 | $285,028 | 11 | Alfa Films | false | false |
| 62 | 50 | Los superagentes, nueva generación | $110 | -74.9% | 4 | -1 | $27 | $863,604 | 12 | Argentina Sono Film S.A.C.I. | false | false |
| 63 | 62 | The Chronicles of Narnia: Prince Caspian | $110 | -21.4% | 2 | - | $55 | $3,701,886 | 17 | Walt Disney Pictures | false | false |
| 64 | 45 | Hunting and Gathering | $89 | -85.6% | 1 | -3 | $89 | $21,915 | 6 | Notro Films | false | false |
| 65 | 68 | The Nest | $86 | +68.6% | 1 | - | $86 | $967,402 | 24 | Distribution Company | false | false |
| 66 | 59 | Conversations with My Gardener | $54 | -74% | 1 | - | $54 | $238,398 | 24 | Alfa Films | false | false |
| 67 | - | Argentina latente | $34 | - | 1 | - | $34 | $33,275 | 72 | Primer Plano Film Group | false | false |
| 68 | 49 | Cassandra's Dream | $33 | -93.1% | 1 | -2 | $33 | $582,477 | 18 | Alfa Films | false | false |
| 69 | - | Pulqui, un instante en la patria de la felicidad | $5 | - | 1 | - | $5 | $1,804 | 65 | Primer Plano Film Group | false | false |
