| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | A Boyfriend for My Wife | $360,717 | -24.4% | 72 | +1 | $5,009 | $4,751,418 | 6 | Walt Disney Pictures | false | false |
| 2 | - | You Don't Mess with the Zohan | $195,360 | - | 30 | - | $6,512 | $195,360 | 1 | Sony Pictures Releasing | true | false |
| 3 | 3 | Tinker Bell | $155,132 | -35.1% | 54 | - | $2,872 | $439,839 | 2 | Walt Disney Pictures | false | false |
| 4 | 2 | Tropic Thunder | $147,013 | -40.3% | 47 | - | $3,127 | $899,070 | 3 | United International Pictures | false | false |
| 5 | - | Taken | $123,194 | - | 30 | - | $4,106 | $123,194 | 1 | 20th Century Fox International | true | false |
| 6 | 4 | Mamma Mia! | $113,961 | -28.5% | 50 | - | $2,279 | $1,224,396 | 5 | United International Pictures | false | false |
| 7 | 6 | Superhero Movie | $81,975 | -35.8% | 40 | - | $2,049 | $230,972 | 2 | Pachamama Cine | false | false |
| 8 | 5 | Reasons for Not Falling in Love | $81,237 | -38.4% | 43 | - | $1,889 | $457,617 | 3 | Distribution Company | false | false |
| 9 | - | My Brother is an Only Child | $63,584 | - | 12 | - | $5,298 | $63,584 | 1 | Alfa Films | true | false |
| 10 | 7 | The Strangers | $62,271 | -45.1% | 31 | - | $2,008 | $203,782 | 2 | Distribution Company | false | false |
| 11 | 8 | REC | $47,590 | -25.3% | 19 | - | $2,504 | $129,058 | 2 | CDI Films | false | false |
| 12 | 9 | Wanted | $35,065 | -42.2% | 44 | -1 | $796 | $522,409 | 4 | United International Pictures | false | false |
| 13 | 11 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $22,559 | -36% | 2 | - | $11,279 | $103,751 | 3 | Walt Disney Pictures | false | false |
| 14 | 10 | Babylon A.D. | $22,513 | -47.4% | 30 | - | $750 | $107,753 | 3 | 20th Century Fox International | false | false |
| 15 | 12 | The Bottle | $16,996 | -49.2% | 24 | +2 | $708 | $59,201 | 2 | Primer Plano Film Group | false | false |
| 16 | 14 | La próxima estación | $15,410 | -36.5% | 7 | +2 | $2,201 | $67,153 | 3 | Primer Plano Film Group | false | false |
| 17 | 15 | Four Minutes | $14,540 | -34.3% | 14 | +2 | $1,038 | $152,559 | 4 | Alfa Films | false | false |
| 18 | 13 | The Dark Knight | $10,358 | -58% | 18 | -5 | $575 | $5,469,860 | 10 | Warner Bros. | false | false |
| 19 | 16 | The X Files: I Want to Believe | $10,210 | -50.6% | 41 | -4 | $249 | $692,464 | 6 | 20th Century Fox International | false | false |
| 20 | 27 | Run Fatboy Run | $9,299 | +98.2% | 16 | +1 | $581 | $70,218 | 4 | Distribution Company | false | false |
| 21 | 37 | Francesca | $9,244 | +330.6% | 6 | +4 | $1,540 | $159,828 | 10 | IFA | false | false |
| 22 | 26 | Black Sheep | $8,245 | +59.8% | 16 | +4 | $515 | $143,362 | 5 | Pachamama Cine | false | false |
| 23 | 17 | L'invité | $8,218 | -53.7% | 12 | -1 | $684 | $119,444 | 4 | Pachamama Cine | false | false |
| 24 | 23 | Journey to the Center of the Earth | $6,628 | +0.9% | 13 | -1 | $509 | $956,041 | 10 | Distribution Company | false | false |
| 25 | 18 | Meet Dave | $6,430 | -41.7% | 26 | -2 | $247 | $285,171 | 7 | 20th Century Fox International | false | false |
| 26 | 28 | Chaos | $6,149 | +35.7% | 15 | +8 | $409 | $90,057 | 6 | - | false | false |
| 27 | 21 | The Headless Woman | $5,981 | -39.9% | 14 | -3 | $427 | $131,719 | 5 | Distribution Company | false | false |
| 28 | 19 | Star Wars: The Clone Wars | $5,780 | -45% | 29 | -12 | $199 | $237,392 | 6 | Warner Bros. | false | false |
| 29 | 20 | The Mummy: Tomb of the Dragon Emperor | $4,734 | -54.1% | 19 | -16 | $249 | $2,881,921 | 8 | United International Pictures | false | false |
| 30 | - | Golden Door | $4,665 | - | 3 | - | $1,555 | $4,665 | 1 | Primer Plano Film Group | true | false |
| 31 | 22 | WALL·E | $3,408 | -65.2% | 16 | -8 | $213 | $4,817,632 | 11 | Walt Disney Pictures | false | false |
| 32 | 24 | Before the Devil Knows You're Dead | $2,837 | -56.1% | 16 | -2 | $177 | $591,226 | 11 | Distribution Company | false | false |
| 33 | 25 | Nim's Island | $2,037 | -62.9% | 12 | -4 | $169 | $152,884 | 7 | United International Pictures | false | false |
| 34 | 32 | Climates | $1,636 | -44.3% | 2 | - | $818 | $19,214 | 4 | 791 Cine | false | false |
| 35 | 31 | A Girl Cut in Two | $1,622 | -55.7% | 4 | -2 | $405 | $293,766 | 9 | Alfa Films | false | false |
| 36 | 55 | The Diving Bell and the Butterfly | $1,501 | +314.6% | 4 | +2 | $375 | $103,674 | 6 | Alfa Films | false | false |
| 37 | 30 | Los superagentes, nueva generación | $1,348 | -63.6% | 8 | -9 | $168 | $892,342 | 10 | Argentina Sono Film S.A.C.I. | false | false |
| 38 | 40 | Cassandra's Dream | $1,198 | -29.4% | 3 | -1 | $399 | $581,694 | 16 | Alfa Films | false | false |
| 39 | 50 | My Blueberry Nights | $1,192 | +59.4% | 5 | - | $238 | $225,616 | 13 | Distribution Company | false | false |
| 40 | 34 | You, the Living | $1,189 | -56.3% | 3 | -2 | $396 | $17,555 | 3 | Zeta Films | false | false |
| 41 | - | Comedy of Innocence | $1,157 | - | 3 | - | $385 | $17,080 | 361 | Primer Plano Film Group | false | false |
| 42 | - | Lars and the Real Girl | $1,122 | - | 4 | - | $280 | $75,071 | 5 | Impacto Cine | false | false |
| 43 | 39 | Valentina: The Movie | $959 | -51.4% | 8 | - | $119 | $376,866 | 11 | Pachamama Cine | false | false |
| 44 | 59 | A Secret | $906 | +205.1% | 3 | +1 | $302 | $206,320 | 14 | Alfa Films | false | false |
| 45 | 35 | The Price to Pay | $828 | -67% | 5 | -3 | $165 | $131,161 | 8 | Impacto Cine | false | false |
| 46 | 33 | 100% lucha, la película | $823 | -71.9% | 9 | -6 | $91 | $948,993 | 11 | Primer Plano Film Group | false | false |
| 47 | 51 | A Guide to Recognizing Your Saints | $769 | +9.7% | 3 | +2 | $256 | $13,467 | 4 | CDI Films | false | false |
| 48 | 36 | Kung Fu Panda | $755 | -68% | 4 | -3 | $188 | $5,798,369 | 12 | United International Pictures | false | false |
| 49 | 41 | The Counterfeiters | $630 | -60.3% | 2 | -3 | $315 | $397,956 | 19 | Alfa Films | false | false |
| 50 | 45 | Hunting and Gathering | $571 | -38.4% | 4 | +3 | $142 | $21,307 | 4 | Notro Films | false | false |
| 51 | 48 | The Incredible Hulk | $556 | -32% | 2 | - | $278 | $919,266 | 14 | United International Pictures | false | false |
| 52 | - | U2 3D | $503 | - | 1 | - | $503 | $157,585 | 26 | IMAX | false | false |
| 53 | 54 | Death at a Funeral | $479 | +18.6% | 2 | - | $239 | $2,150,676 | 29 | Compañía General de la Imagen (CGI) | false | false |
| 54 | - | Sex and the City | $392 | - | 1 | - | $392 | $1,649,755 | 15 | Distribution Company | false | false |
| 55 | 56 | Paranoid Park | $371 | +7.5% | 2 | +1 | $185 | $9,064 | 5 | Alfa Films | false | false |
| 56 | 29 | The Other Boleyn Girl | $281 | -93.4% | 2 | -11 | $140 | $336,304 | 7 | Distribution Company | false | false |
| 57 | 44 | Under the Same Moon | $245 | -79% | 2 | -10 | $122 | $27,164 | 5 | 20th Century Fox International | false | false |
| 58 | 49 | High School Musical: El Desafío | $220 | -71.4% | 3 | - | $73 | $1,826,853 | 10 | Walt Disney Pictures | false | false |
| 59 | 43 | The Happening | $182 | -84.7% | 1 | -6 | $182 | $1,341,309 | 14 | 20th Century Fox International | false | false |
| 60 | 64 | Conversations with My Gardener | $165 | +35.2% | 1 | - | $165 | $246,197 | 22 | Alfa Films | false | false |
| 61 | 42 | Abrígate | $155 | -88.2% | 1 | -2 | $155 | $1,991 | 2 | Walt Disney Pictures | false | false |
| 62 | - | Leonera | $136 | - | 1 | - | $136 | $500,913 | 17 | Walt Disney Pictures | false | false |
| 63 | 63 | The Band's Visit | $135 | +4.7% | 2 | - | $67 | $136,493 | 11 | Alfa Films | false | false |
| 64 | 58 | The Chronicles of Narnia: Prince Caspian | $135 | -55% | 1 | -2 | $135 | $3,701,424 | 15 | Walt Disney Pictures | false | false |
| 65 | 60 | Hancock | $127 | -55.1% | 2 | -1 | $63 | $2,309,497 | 12 | Sony Pictures Releasing | false | false |
| 66 | 52 | I Served the King of England | $77 | -87.5% | 3 | +1 | $25 | $69,076 | 8 | Distribution Company | false | false |
| 67 | 46 | Get Smart | $63 | -92.7% | 1 | -1 | $63 | $2,328,819 | 13 | Warner Bros. | false | false |
