| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | A Boyfriend for My Wife | $477,012 | -24.8% | 71 | -15 | $6,718 | $4,274,525 | 5 | Walt Disney Pictures | false | false |
| 2 | 2 | Tropic Thunder | $246,363 | -32% | 47 | - | $5,241 | $702,302 | 2 | United International Pictures | false | false |
| 3 | - | Tinker Bell | $238,963 | - | 54 | - | $4,425 | $238,963 | 1 | Walt Disney Pictures | true | false |
| 4 | 3 | Mamma Mia! | $159,276 | -15.7% | 50 | +2 | $3,185 | $1,077,481 | 4 | United International Pictures | false | false |
| 5 | 4 | Reasons for Not Falling in Love | $131,843 | -22.2% | 43 | - | $3,066 | $346,172 | 2 | Distribution Company | false | false |
| 6 | - | Superhero Movie | $127,633 | - | 40 | - | $3,190 | $127,633 | 1 | Pachamama Cine | true | false |
| 7 | - | The Strangers | $113,395 | - | 31 | - | $3,657 | $113,395 | 1 | Distribution Company | true | false |
| 8 | - | REC | $63,733 | - | 19 | - | $3,354 | $63,733 | 1 | CDI Films | true | false |
| 9 | 5 | Wanted | $60,687 | -48.2% | 45 | - | $1,348 | $473,560 | 3 | United International Pictures | false | false |
| 10 | 6 | Babylon A.D. | $42,840 | -42.7% | 30 | - | $1,428 | $137,783 | 2 | 20th Century Fox International | false | false |
| 11 | 11 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $35,250 | +0.5% | 2 | - | $17,625 | $76,749 | 2 | Walt Disney Pictures | false | false |
| 12 | - | The Bottle | $33,463 | - | 22 | - | $1,521 | $33,463 | 1 | Primer Plano Film Group | true | false |
| 13 | 7 | The Dark Knight | $24,679 | -57.2% | 23 | -21 | $1,073 | $5,452,898 | 9 | Warner Bros. | false | false |
| 14 | 18 | La próxima estación | $24,278 | +75.8% | 5 | +2 | $4,855 | $45,468 | 2 | Primer Plano Film Group | false | false |
| 15 | 10 | Four Minutes | $22,118 | -38% | 12 | -2 | $1,843 | $133,428 | 3 | Alfa Films | false | false |
| 16 | 8 | The X Files: I Want to Believe | $20,651 | -52.9% | 45 | - | $458 | $675,798 | 5 | 20th Century Fox International | false | false |
| 17 | 12 | L'invité | $17,766 | -33.9% | 13 | -1 | $1,366 | $107,300 | 3 | Pachamama Cine | false | false |
| 18 | 14 | Meet Dave | $11,029 | -41.8% | 28 | - | $393 | $276,618 | 6 | 20th Century Fox International | false | false |
| 19 | 15 | Star Wars: The Clone Wars | $10,504 | -40.4% | 41 | -2 | $256 | $229,635 | 5 | Warner Bros. | false | false |
| 20 | 9 | The Mummy: Tomb of the Dragon Emperor | $10,304 | -76.4% | 35 | -37 | $294 | $2,874,024 | 7 | United International Pictures | false | false |
| 21 | 17 | The Headless Woman | $9,950 | -29.5% | 17 | - | $585 | $123,586 | 4 | Distribution Company | false | false |
| 22 | 13 | WALL·E | $9,796 | -57% | 24 | -8 | $408 | $4,812,544 | 10 | Walt Disney Pictures | false | false |
| 23 | 24 | Journey to the Center of the Earth | $6,572 | -27.8% | 14 | -8 | $469 | $948,383 | 9 | Distribution Company | false | false |
| 24 | 20 | Before the Devil Knows You're Dead | $6,468 | -39.8% | 18 | +1 | $359 | $586,982 | 10 | Distribution Company | false | false |
| 25 | 27 | Nim's Island | $5,492 | -24.6% | 16 | -6 | $343 | $149,863 | 6 | United International Pictures | false | false |
| 26 | 16 | Black Sheep | $5,160 | -64% | 12 | -10 | $430 | $133,845 | 4 | Pachamama Cine | false | false |
| 27 | 19 | Run Fatboy Run | $4,691 | -58.9% | 15 | -4 | $312 | $59,726 | 3 | Distribution Company | false | false |
| 28 | 30 | Chaos | $4,530 | -3.3% | 7 | -2 | $647 | $83,703 | 5 | - | false | false |
| 29 | 23 | The Other Boleyn Girl | $4,270 | -54.4% | 13 | -12 | $328 | $334,722 | 6 | Distribution Company | false | false |
| 30 | 28 | Los superagentes, nueva generación | $3,700 | -37.9% | 17 | +1 | $217 | $890,290 | 9 | Argentina Sono Film S.A.C.I. | false | false |
| 31 | 39 | A Girl Cut in Two | $3,660 | +53.6% | 6 | -2 | $610 | $290,641 | 8 | Alfa Films | false | false |
| 32 | 33 | Climates | $2,937 | -26.1% | 2 | - | $1,468 | $16,917 | 3 | 791 Cine | false | false |
| 33 | 38 | 100% lucha, la película | $2,931 | +21.3% | 15 | +3 | $195 | $946,874 | 10 | Primer Plano Film Group | false | false |
| 34 | 21 | You, the Living | $2,722 | -72.3% | 5 | -2 | $544 | $15,568 | 2 | Zeta Films | false | false |
| 35 | 44 | The Price to Pay | $2,507 | +47.9% | 8 | - | $313 | $129,687 | 7 | Impacto Cine | false | false |
| 36 | 25 | Kung Fu Panda | $2,357 | -71.3% | 7 | -10 | $336 | $5,797,289 | 11 | United International Pictures | false | false |
| 37 | 32 | Francesca | $2,147 | -49.2% | 2 | -3 | $1,073 | $151,291 | 9 | IFA | false | false |
| 38 | - | Backstage 2008 Re-release | $2,057 | - | 3 | - | $685 | $2,057 | 1 | Distribution Company | true | false |
| 39 | 40 | Valentina: The Movie | $1,972 | -10.8% | 8 | -1 | $246 | $375,285 | 10 | Pachamama Cine | false | false |
| 40 | 31 | Cassandra's Dream | $1,697 | -60.2% | 4 | -5 | $424 | $579,736 | 15 | Alfa Films | false | false |
| 41 | 37 | The Counterfeiters | $1,587 | -45.1% | 5 | -4 | $317 | $400,019 | 18 | Alfa Films | false | false |
| 42 | - | Abrígate | $1,312 | - | 3 | - | $437 | $1,312 | 1 | Walt Disney Pictures | true | false |
| 43 | 34 | The Happening | $1,190 | -68% | 7 | -4 | $170 | $1,340,364 | 13 | 20th Century Fox International | false | false |
| 44 | 45 | Under the Same Moon | $1,166 | -30.8% | 12 | +5 | $97 | $26,713 | 4 | 20th Century Fox International | false | false |
| 45 | 36 | Hunting and Gathering | $927 | -68.8% | 1 | -5 | $927 | $20,439 | 3 | Notro Films | false | false |
| 46 | 49 | Get Smart | $865 | -38% | 2 | -3 | $432 | $2,328,663 | 12 | Warner Bros. | false | false |
| 47 | 42 | 88 Minutes | $840 | -55.4% | 2 | -2 | $420 | $396,117 | 16 | Distribution Company | false | false |
| 48 | 48 | The Incredible Hulk | $818 | -42.5% | 2 | -5 | $409 | $918,221 | 13 | United International Pictures | false | false |
| 49 | 46 | High School Musical: El Desafío | $768 | -53% | 3 | -5 | $256 | $1,826,613 | 9 | Walt Disney Pictures | false | false |
| 50 | 51 | My Blueberry Nights | $748 | +13.5% | 5 | +2 | $149 | $224,152 | 12 | Distribution Company | false | false |
| 51 | 43 | A Guide to Recognizing Your Saints | $701 | -60.5% | 1 | -2 | $701 | $12,290 | 3 | CDI Films | false | false |
| 52 | 41 | I Served the King of England | $616 | -69.1% | 2 | -3 | $308 | $68,706 | 7 | Distribution Company | false | false |
| 53 | 47 | The Oxford Murders | $586 | -63.8% | 2 | -2 | $293 | $578,913 | 19 | Pachamama Cine | false | false |
| 54 | 56 | Death at a Funeral | $404 | +54.8% | 2 | +1 | $202 | $2,150,005 | 28 | Compañía General de la Imagen (CGI) | false | false |
| 55 | 29 | The Diving Bell and the Butterfly | $362 | -93.3% | 2 | -8 | $181 | $101,287 | 5 | Alfa Films | false | false |
| 56 | - | Paranoid Park | $345 | - | 1 | - | $345 | $8,672 | 4 | Alfa Films | false | false |
| 57 | 54 | Café de los maestros | $337 | -39.7% | 3 | - | $112 | $111,061 | 12 | Alfa Films | false | false |
| 58 | 55 | The Chronicles of Narnia: Prince Caspian | $300 | -36.6% | 3 | +1 | $100 | $3,701,209 | 14 | Walt Disney Pictures | false | false |
| 59 | 63 | A Secret | $297 | +1,191.3% | 2 | +1 | $148 | $205,074 | 13 | Alfa Films | false | false |
| 60 | 50 | Hancock | $283 | -67.1% | 3 | -2 | $94 | $2,287,658 | 11 | Sony Pictures Releasing | false | false |
| 61 | - | Made of Honor | $278 | - | 1 | - | $278 | $358,365 | 15 | Sony Pictures Releasing | false | false |
| 62 | 35 | The Mist | $266 | -92% | 2 | -5 | $133 | $422,013 | 15 | Distribution Company | false | false |
| 63 | 53 | The Band's Visit | $129 | -78.3% | 2 | -1 | $64 | $136,164 | 10 | Alfa Films | false | false |
| 64 | 57 | Conversations with My Gardener | $122 | -49.4% | 1 | - | $122 | $245,775 | 21 | Alfa Films | false | false |
| 65 | 58 | Odette Toulemonde | $53 | -74.5% | 1 | -1 | $53 | $30,472 | 16 | Notro Films | false | false |
| 66 | 62 | Juno | $13 | -60.6% | 1 | - | $13 | $474,042 | 31 | Alfa Films | false | false |
