| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Dark Knight | $562,918 | -37.4% | 91 | - | $6,185 | $5,463,452 | 4 | Warner Bros. | false | false |
| 2 | 3 | Mamma Mia! | $527,148 | -20.7% | 103 | +1 | $5,117 | $5,461,885 | 5 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | WALL·E | $386,367 | -53.8% | 188 | - | $2,055 | $2,796,388 | 3 | Walt Disney Pictures | false | false |
| 4 | - | Wild Child | $372,143 | - | 46 | - | $8,090 | $389,620 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | - | Get Smart | $348,007 | - | 70 | - | $4,971 | $382,687 | 1 | Warner Bros. | true | false |
| 6 | 4 | The Mummy: Tomb of the Dragon Emperor | $294,161 | -46.3% | 85 | +1 | $3,460 | $2,196,504 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | You Don't Mess with the Zohan | $202,852 | -42.9% | 40 | - | $5,071 | $738,650 | 2 | Sony Pictures Releasing | false | false |
| 8 | 5 | Kung Fu Panda | $163,139 | -60.8% | 117 | -19 | $1,394 | $5,627,898 | 6 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | De brief voor de koning | $140,085 | -47.4% | 104 | -2 | $1,346 | $1,842,585 | 5 | Benelux Film Distributors | false | false |
| 10 | 8 | Hancock | $106,109 | -54.6% | 67 | -13 | $1,583 | $4,909,575 | 6 | Sony Pictures Releasing | false | false |
| 11 | 9 | The X Files: I Want to Believe | $84,760 | -55.5% | 58 | - | $1,461 | $352,987 | 2 | 20th Century Fox International | false | false |
| 12 | 10 | Sex and the City | $59,337 | -40.6% | 40 | -13 | $1,483 | $6,038,836 | 10 | Paradiso Entertainment | false | false |
| 13 | - | Mongol: The Rise of Genghis Khan | $50,652 | - | 13 | - | $3,896 | $56,350 | 1 | Benelux Film Distributors | true | false |
| 14 | 11 | Hoe overleef ik...? | $46,376 | -48.6% | 62 | -6 | $748 | $2,428,769 | 8 | Warner Bros. | false | false |
| 15 | 18 | Into the Wild | $34,780 | -2.4% | 20 | +1 | $1,739 | $1,336,205 | 17 | A-Film Distribution | false | false |
| 16 | 17 | I've Loved You So Long | $30,315 | -16.6% | 18 | -2 | $1,684 | $805,040 | 11 | Benelux Film Distributors | false | false |
| 17 | 12 | The Chronicles of Narnia: Prince Caspian | $28,050 | -59.5% | 51 | -21 | $550 | $2,893,758 | 7 | Walt Disney Pictures | false | false |
| 18 | 14 | Snuf de hond in oorlogstijd | $24,408 | -56.5% | 44 | -5 | $554 | $788,567 | 8 | RCV Film Distribution | false | false |
| 19 | 16 | Indiana Jones and the Kingdom of the Crystal Skull | $22,276 | -40.2% | 17 | -7 | $1,310 | $6,804,023 | 13 | Universal Pictures International (UPI) | false | false |
| 20 | 13 | Nim's Island | $20,582 | -67.2% | 42 | - | $490 | $124,801 | 2 | Independent Films | false | false |
| 21 | 21 | 21 | $4,607 | -48.3% | 3 | -3 | $1,535 | $1,246,958 | 8 | Sony Pictures Releasing | false | false |
