| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Dark Knight | $4,429,137 | - | 570 | - | $7,770 | $7,238,815 | 1 | Warner Bros. | true | false |
| 2 | - | Mamma Mia! | $2,749,066 | - | 377 | - | $7,291 | $5,250,208 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 1 | WALL·E | $1,971,845 | -38.4% | 498 | +4 | $3,959 | $9,637,549 | 2 | Walt Disney Pictures | false | false |
| 4 | 2 | The Mummy: Tomb of the Dragon Emperor | $1,540,875 | -44.8% | 407 | -112 | $3,785 | $15,714,908 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | Taken | $1,008,393 | -19% | 320 | +2 | $3,151 | $3,089,522 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | Hancock | $714,610 | -32.6% | 408 | -72 | $1,751 | $24,692,917 | 5 | Sony Pictures Releasing | false | false |
| 7 | 6 | Kung Fu Panda | $365,576 | -34.3% | 283 | -73 | $1,291 | $20,507,899 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Get Smart | $240,288 | -43.1% | 266 | -78 | $903 | $4,960,207 | 4 | Warner Bros. | false | false |
| 9 | 8 | Virgin Territory | $156,212 | -44.6% | 182 | -3 | $858 | $625,793 | 2 | Aurum Films | false | false |
| 10 | 10 | P.S. I Love You | $113,699 | -28.6% | 115 | -43 | $988 | $3,837,339 | 6 | Filmax | false | false |
| 11 | 9 | The X Files: I Want to Believe | $72,124 | -59.9% | 143 | -156 | $504 | $3,021,762 | 4 | 20th Century Fox International | false | false |
| 12 | 11 | The Chronicles of Narnia: Prince Caspian | $71,303 | -40.6% | 139 | -92 | $512 | $14,879,605 | 7 | Walt Disney Pictures | false | false |
| 13 | 14 | Goodbye Beautiful Days | $66,630 | -7.2% | 40 | - | $1,665 | $436,029 | 3 | Golem Distribución | false | false |
| 14 | 12 | Whisper | $60,589 | -46.1% | 57 | -34 | $1,062 | $991,347 | 3 | Vértigo Films | false | false |
| 15 | 15 | Saint-Jacques... La Mecque 2007 Re-release | $57,554 | -11.6% | 30 | - | $1,918 | $180,582 | 2 | Baditri | false | false |
| 16 | 13 | Sex and the City | $54,635 | -29.8% | 65 | -42 | $840 | $9,511,265 | 9 | TriPictures | false | false |
| 17 | 19 | I Served the King of England | $36,326 | -4.3% | 31 | -1 | $1,171 | $514,401 | 5 | Wanda Visión S.A. | false | false |
| 18 | 16 | Indiana Jones and the Kingdom of the Crystal Skull | $34,147 | -37.3% | 52 | -20 | $656 | $32,484,271 | 13 | Universal Pictures International (UPI) | false | false |
| 19 | 20 | Before the Devil Knows You're Dead | $31,431 | -5.5% | 22 | -4 | $1,428 | $3,644,723 | 13 | Baditri | false | false |
| 20 | 18 | In Bruges | $29,166 | -38.2% | 27 | -24 | $1,080 | $1,083,446 | 5 | Universal Pictures International (UPI) | false | false |
| 21 | 17 | Shiver | $22,039 | -55.6% | 50 | -45 | $440 | $1,579,014 | 5 | Walt Disney Pictures | false | false |
| 22 | 21 | Elite Squad | $20,438 | -30.6% | 34 | -14 | $601 | $668,210 | 5 | Alta Films | false | false |
| 23 | 23 | O Jerusalem | $11,353 | -24.4% | 15 | -6 | $756 | $742,301 | 7 | Notro Films | false | false |
| 24 | 22 | Redbelt | $9,891 | -60.6% | 22 | -7 | $449 | $50,491 | 2 | Sony Pictures Releasing | false | false |
| 25 | 27 | A Boyfriend for Yamsina | $9,236 | -8.4% | 17 | -3 | $543 | $220,773 | 6 | Alta Films | false | false |
| 26 | 26 | Promise Me This | $8,431 | -23.7% | 12 | +1 | $702 | $312,691 | 6 | Baditri | false | false |
| 27 | 29 | Quiet Chaos | $7,939 | -5.7% | 8 | -1 | $992 | $537,805 | 9 | Alta Films | false | false |
| 28 | 24 | Fierce People | $7,742 | -45.8% | 6 | -4 | $1,290 | $30,734 | 2 | Filmax | false | false |
| 29 | 25 | The Happening | $7,483 | -37.4% | 14 | -17 | $534 | $9,589,910 | 10 | 20th Century Fox International | false | false |
| 30 | 37 | Emotional Arithmetic | $4,114 | +8.9% | 9 | - | $457 | $860,662 | 11 | Golem Distribución | false | false |
| 31 | 38 | Bonneville | $3,737 | +0.2% | 7 | +2 | $533 | $146,708 | 7 | Filmax | false | false |
| 32 | 43 | The Ugly Duckling and Me! | $3,698 | +22.1% | 17 | -19 | $217 | $1,096,718 | 9 | Filmax | false | false |
| 33 | 34 | Giraffes | $3,583 | -18.7% | 5 | - | $716 | $11,711 | 2 | Barton Films | false | false |
| 34 | 39 | Garage | $3,343 | -2.7% | 6 | - | $557 | $59,153 | 4 | Avalon | false | false |
| 35 | 30 | Funny Games | $3,183 | -53.3% | 16 | -8 | $198 | $919,437 | 7 | Warner Bros. | false | false |
| 36 | 31 | Gente de mala calidad | $2,898 | -57% | 6 | -6 | $483 | $735,897 | 6 | Manga Entertainment | false | false |
| 37 | 32 | Margot at the Wedding | $2,759 | -55.6% | 3 | -7 | $919 | $312,048 | 9 | Universal Pictures International (UPI) | false | false |
| 38 | 61 | Satanás | $2,514 | +260.7% | 4 | +3 | $628 | $36,791 | 7 | Alta Films | false | false |
| 39 | 42 | Breath | $2,416 | -21.2% | 3 | -1 | $805 | $90,515 | 7 | Golem Distribución | false | false |
| 40 | 47 | How to Cook Your Life | $2,408 | -7.3% | 1 | - | $2,408 | $54,907 | 7 | Karma Films | false | false |
| 41 | 33 | Chef's Special | $2,396 | -51.3% | 1 | -5 | $2,396 | $7,804,678 | 19 | Warner Bros. | false | false |
| 42 | 40 | The Mist | $2,327 | -26% | 4 | -1 | $581 | $3,485,534 | 12 | Notro Films | false | false |
| 43 | 41 | 3:19 2008 Re-release | $2,154 | -29.9% | 5 | - | $430 | $236,959 | 9 | N/A | false | false |
| 44 | 28 | Doomsday | $2,008 | -77.7% | 8 | -8 | $251 | $277,929 | 4 | Universal Pictures International (UPI) | false | false |
| 45 | 52 | Under the Snow | $1,880 | +6.6% | 2 | - | $940 | $38,352 | 6 | Independent Films | false | false |
| 46 | 46 | Occasional Work of a Female Slave | $1,809 | -35% | 2 | - | $904 | $17,093 | 3 | Sherlock Films | false | false |
| 47 | 44 | Be Kind Rewind | $1,799 | -38.3% | 3 | +1 | $599 | $544,972 | 19 | Universal Pictures International (UPI) | false | false |
| 48 | 36 | Late Bloomers | $1,776 | -56.4% | 5 | -2 | $355 | $443,883 | 15 | - | false | false |
| 49 | 49 | Made of Honor | $1,684 | -35% | 6 | +1 | $280 | $6,321,041 | 12 | Sony Pictures Releasing | false | false |
| 50 | 48 | Courthouse on Horseback | $1,211 | -53.3% | 2 | -3 | $605 | $344,844 | 13 | Karma Films | false | false |
| 51 | 35 | Harold & Kumar Escape from Guantanamo Bay | $1,124 | -72.6% | 5 | -15 | $224 | $853,844 | 6 | TriPictures | false | false |
| 52 | 60 | The Yacoubian Building | $1,047 | +32.7% | 2 | - | $523 | $50,445 | 12 | Barton Films | false | false |
| 53 | 57 | Desert Dream | $1,046 | +11.4% | 2 | - | $523 | $14,957 | 4 | Golem Distribución | false | false |
| 54 | 55 | 21 | $1,013 | -25.2% | 3 | - | $337 | $6,775,842 | 19 | Sony Pictures Releasing | false | false |
| 55 | 53 | I'm a Cyborg, But That's OK | $982 | -34.9% | 3 | - | $327 | $29,798 | 5 | Versus Entertainment | false | false |
| 56 | 51 | Iron Man | $942 | -46.7% | 4 | -1 | $235 | $11,779,578 | 16 | Sony Pictures Releasing | false | false |
| 57 | 63 | Untraceable | $939 | +52.7% | 2 | - | $469 | $1,865,096 | 20 | Universal Pictures International (UPI) | false | false |
| 58 | 59 | Cashback | $939 | +14.1% | 1 | - | $939 | $215,148 | 19 | Laurenfilm | false | false |
| 59 | 56 | 88 Minutes | $831 | -23.5% | 1 | - | $831 | $3,912,288 | 16 | Filmax | false | false |
| 60 | 50 | Timecrimes | $820 | -59.1% | 6 | - | $136 | $412,257 | 8 | N/A | false | false |
| 61 | 45 | The Incredible Hulk | $702 | -75.9% | 5 | -16 | $140 | $7,618,162 | 9 | Sony Pictures Releasing | false | false |
| 62 | 67 | A Thousand Years of Good Prayers | $577 | +89.2% | 1 | - | $577 | $1,163,809 | 18 | Karma Films | false | false |
| 63 | 54 | Prom Night | $539 | -60.7% | 1 | - | $539 | $1,862,016 | 14 | Sony Pictures Releasing | false | false |
| 64 | 62 | Into the Wild | $445 | -33.7% | 1 | -20 | $445 | $776,274 | 30 | Universal Pictures International (UPI) | false | false |
| 65 | 68 | Drillbit Taylor | $94 | -67% | 2 | - | $47 | $439,910 | 14 | Universal Pictures International (UPI) | false | false |
| 66 | 70 | Reyita | $75 | +21% | 1 | - | $75 | $324 | 2 | Sagrera TV | false | false |
