| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Mummy: Tomb of the Dragon Emperor | $214,450 | - | 83 | - | $2,583 | $214,450 | 1 | United International Pictures | true | false |
| 2 | 1 | The Dark Knight | $170,865 | -41.2% | 87 | +1 | $1,963 | $1,145,015 | 3 | NuMetro Distribution | false | false |
| 3 | 2 | You Don't Mess with the Zohan | $88,822 | -43% | 59 | -1 | $1,505 | $292,812 | 2 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Hancock | $69,251 | -36.4% | 72 | -10 | $961 | $1,882,623 | 6 | Ster-Kinekor Pictures | false | false |
| 5 | 4 | Wanted | $54,611 | -35.8% | 69 | - | $791 | $939,985 | 5 | United International Pictures | false | false |
| 6 | 6 | Journey to the Center of the Earth | $49,390 | -37.5% | 36 | -5 | $1,371 | $429,279 | 4 | NuMetro Distribution | false | false |
| 7 | 5 | WALL·E | $48,463 | -39.7% | 60 | -9 | $807 | $769,152 | 5 | Ster-Kinekor Pictures | false | false |
| 8 | 8 | Kung Fu Panda | $30,973 | -42.4% | 48 | -7 | $645 | $2,016,107 | 7 | United International Pictures | false | false |
| 9 | 7 | The X Files: I Want to Believe | $23,846 | -63.1% | 56 | - | $425 | $108,124 | 2 | NuMetro Distribution | false | false |
| 10 | 10 | The Bank Job | $23,055 | -21.6% | 24 | -4 | $960 | $200,966 | 4 | United International Pictures | false | false |
| 11 | - | Singh Is King | $22,206 | - | 10 | - | $2,220 | $22,206 | 1 | Ster-Kinekor Pictures | true | false |
| 12 | 9 | Miss Pettigrew Lives for a Day | $20,789 | -33.8% | 16 | - | $1,299 | $65,251 | 2 | Ster-Kinekor Pictures | false | false |
| 13 | 11 | College Road Trip | $19,281 | -25.7% | 21 | -3 | $918 | $655,230 | 8 | Ster-Kinekor Pictures | false | false |
| 14 | 12 | Get Smart | $16,549 | -26.2% | 25 | -9 | $661 | $682,945 | 6 | NuMetro Distribution | false | false |
| 15 | 13 | Drillbit Taylor | $6,785 | -41.4% | 15 | -1 | $452 | $101,055 | 4 | United International Pictures | false | false |
| 16 | - | Annie Leibovitz: Life Through a Lens | $6,757 | - | 5 | - | $1,351 | $6,757 | 1 | Ster-Kinekor Pictures | true | false |
| 17 | 15 | Caramel | $5,016 | -24.3% | 3 | - | $1,672 | $25,298 | 3 | Ster-Kinekor Pictures | false | false |
| 18 | 14 | Harold & Kumar Escape from Guantanamo Bay | $2,796 | -58.4% | 8 | -4 | $349 | $338,367 | 7 | NuMetro Distribution | false | false |
| 19 | 18 | The Incredible Hulk | $2,567 | -51.7% | 7 | -4 | $366 | $928,871 | 9 | United International Pictures | false | false |
| 20 | 19 | Married Life | $2,231 | -37.8% | 5 | -3 | $446 | $91,643 | 9 | NuMetro Distribution | false | false |
| 21 | 21 | Paris, Je T'aime | $1,982 | -26% | 5 | - | $396 | $76,700 | 11 | NuMetro Distribution | false | false |
| 22 | 20 | Sex and the City | $1,822 | -46.9% | 3 | -2 | $607 | $968,696 | 11 | NuMetro Distribution | false | false |
| 23 | 23 | Forgetting Sarah Marshall | $338 | -68.5% | 2 | -3 | $169 | $297,558 | 8 | United International Pictures | false | false |
| 24 | 22 | Definitely, Maybe | $275 | -89% | 2 | -5 | $137 | $391,998 | 10 | United International Pictures | false | false |
