| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Dark Knight | $290,368 | -29.1% | 86 | -1 | $3,376 | $920,461 | 2 | NuMetro Distribution | false | false |
| 2 | - | You Don't Mess with the Zohan | $155,825 | - | 60 | - | $2,597 | $155,825 | 1 | Ster-Kinekor Pictures | true | false |
| 3 | 2 | Hancock | $108,838 | -23.5% | 82 | -4 | $1,327 | $1,900,816 | 5 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Wanted | $85,126 | -29.4% | 69 | -4 | $1,233 | $909,742 | 4 | United International Pictures | false | false |
| 5 | 4 | WALL·E | $80,373 | -25.6% | 69 | -5 | $1,164 | $748,404 | 4 | Ster-Kinekor Pictures | false | false |
| 6 | 5 | Journey to the Center of the Earth | $78,981 | -20.4% | 41 | -9 | $1,926 | $378,557 | 3 | NuMetro Distribution | false | false |
| 7 | - | The X Files: I Want to Believe | $64,638 | - | 56 | - | $1,154 | $64,638 | 1 | NuMetro Distribution | true | false |
| 8 | 6 | Kung Fu Panda | $53,762 | -33.5% | 55 | -14 | $977 | $2,107,177 | 6 | United International Pictures | false | false |
| 9 | - | Miss Pettigrew Lives for a Day | $31,411 | - | 16 | - | $1,963 | $31,411 | 1 | Ster-Kinekor Pictures | true | false |
| 10 | 8 | The Bank Job | $29,389 | -31.3% | 28 | -2 | $1,049 | $174,909 | 3 | United International Pictures | false | false |
| 11 | 10 | College Road Trip | $25,938 | -4.4% | 24 | -1 | $1,080 | $668,774 | 7 | Ster-Kinekor Pictures | false | false |
| 12 | 7 | Get Smart | $22,423 | -54.9% | 34 | -20 | $659 | $704,423 | 5 | NuMetro Distribution | false | false |
| 13 | 9 | Drillbit Taylor | $11,575 | -58% | 16 | -9 | $723 | $98,970 | 3 | United International Pictures | false | false |
| 14 | 12 | Harold & Kumar Escape from Guantanamo Bay | $6,727 | -34.4% | 12 | -7 | $560 | $356,730 | 6 | NuMetro Distribution | false | false |
| 15 | 15 | Caramel | $6,622 | -16.9% | 3 | - | $2,207 | $18,930 | 2 | Ster-Kinekor Pictures | false | false |
| 16 | 14 | Kismat Konnection | $6,567 | -31% | 9 | -1 | $729 | $40,670 | 3 | Ster-Kinekor Pictures | false | false |
| 17 | 11 | Skinwalkers | $5,862 | -46.2% | 11 | -4 | $532 | $42,497 | 3 | Ster-Kinekor Pictures | false | false |
| 18 | 17 | The Incredible Hulk | $5,313 | -9.4% | 11 | -7 | $483 | $989,459 | 8 | United International Pictures | false | false |
| 19 | 18 | Married Life | $3,586 | -36.8% | 8 | -1 | $448 | $94,358 | 8 | NuMetro Distribution | false | false |
| 20 | 13 | Sex and the City | $3,430 | -65.4% | 5 | -8 | $686 | $1,033,590 | 10 | NuMetro Distribution | false | false |
| 21 | - | Paris, Je T'aime | $2,677 | - | 5 | - | $535 | $70,410 | 10 | NuMetro Distribution | false | false |
| 22 | 22 | Definitely, Maybe | $2,511 | +10.6% | 7 | -2 | $358 | $418,189 | 9 | United International Pictures | false | false |
| 23 | 23 | Forgetting Sarah Marshall | $1,074 | -43.6% | 5 | -5 | $214 | $317,582 | 7 | United International Pictures | false | false |
| 24 | 24 | Indiana Jones and the Kingdom of the Crystal Skull | $406 | -44.2% | 1 | -1 | $406 | $1,248,981 | 11 | United International Pictures | false | false |
| 25 | 25 | First Sunday | $342 | -15.3% | 1 | - | $342 | $174,801 | 15 | United International Pictures | false | false |
