| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Dark Knight | $409,596 | - | 87 | - | $4,708 | $409,596 | 1 | NuMetro Distribution | true | false |
| 2 | 2 | Hancock | $142,319 | -11.5% | 86 | -5 | $1,654 | $1,653,000 | 4 | Ster-Kinekor Pictures | false | false |
| 3 | 1 | Wanted | $120,516 | -26.3% | 73 | - | $1,650 | $722,740 | 3 | United International Pictures | false | false |
| 4 | 3 | WALL·E | $108,053 | -20.3% | 74 | -12 | $1,460 | $609,991 | 3 | Ster-Kinekor Pictures | false | false |
| 5 | 4 | Journey to the Center of the Earth | $99,274 | -14.4% | 50 | - | $1,985 | $253,995 | 2 | NuMetro Distribution | false | false |
| 6 | 5 | Kung Fu Panda | $80,899 | -17.5% | 69 | -13 | $1,172 | $1,930,024 | 5 | United International Pictures | false | false |
| 7 | 6 | Get Smart | $49,713 | -12.2% | 54 | -6 | $920 | $631,925 | 4 | NuMetro Distribution | false | false |
| 8 | 7 | The Bank Job | $42,765 | -7.4% | 30 | - | $1,425 | $116,723 | 2 | United International Pictures | false | false |
| 9 | 8 | Drillbit Taylor | $27,563 | -21.1% | 25 | - | $1,102 | $74,691 | 2 | United International Pictures | false | false |
| 10 | 9 | College Road Trip | $27,118 | +7.9% | 25 | -5 | $1,084 | $601,676 | 6 | Ster-Kinekor Pictures | false | false |
| 11 | 13 | Skinwalkers | $10,905 | -6% | 15 | - | $727 | $28,504 | 2 | Ster-Kinekor Pictures | false | false |
| 12 | 11 | Harold & Kumar Escape from Guantanamo Bay | $10,259 | -33.3% | 19 | -5 | $539 | $327,866 | 5 | NuMetro Distribution | false | false |
| 13 | 12 | Sex and the City | $9,907 | -34% | 13 | -5 | $762 | $974,052 | 9 | NuMetro Distribution | false | false |
| 14 | 10 | Kismat Konnection | $9,513 | -42.1% | 10 | - | $951 | $29,680 | 2 | Ster-Kinekor Pictures | false | false |
| 15 | - | Caramel | $7,970 | - | 3 | - | $2,656 | $7,970 | 1 | Ster-Kinekor Pictures | true | false |
| 16 | 14 | What Happens in Vegas | $6,037 | -47.2% | 11 | -8 | $548 | $1,472,182 | 11 | NuMetro Distribution | false | false |
| 17 | 15 | The Incredible Hulk | $5,866 | -14.2% | 18 | -2 | $325 | $934,133 | 7 | United International Pictures | false | false |
| 18 | 17 | Married Life | $5,674 | +15.1% | 9 | +1 | $630 | $83,978 | 7 | NuMetro Distribution | false | false |
| 19 | 16 | Bella | $5,165 | -6.7% | 7 | - | $737 | $40,380 | 4 | Ster-Kinekor Pictures | false | false |
| 20 | - | Money Hai Toh Honey Hai | $4,470 | - | 5 | - | $894 | $6,435 | 1 | NuMetro Distribution | true | false |
| 21 | 19 | Lust, Caution | $3,930 | -16.4% | 5 | - | $786 | $31,615 | 2 | Ster-Kinekor Pictures | false | false |
| 22 | 23 | Definitely, Maybe | $2,271 | -33% | 9 | +1 | $252 | $393,658 | 8 | United International Pictures | false | false |
| 23 | 22 | Forgetting Sarah Marshall | $1,903 | -47.7% | 10 | -3 | $190 | $300,618 | 6 | United International Pictures | false | false |
| 24 | 24 | Indiana Jones and the Kingdom of the Crystal Skull | $727 | -75.8% | 2 | -7 | $363 | $1,190,020 | 10 | United International Pictures | false | false |
| 25 | 25 | First Sunday | $404 | -14.8% | 1 | - | $404 | $174,155 | 14 | United International Pictures | false | false |
